Abstract:
OBJECTIVE:The aim of this study was to explore the feasibility of using low dose radiation and low concentration contrast media in enhanced CT examinations in children with congenital heart disease. MATERIALS AND METHODS:Ninety patients with congenital heart disease were randomly divided into three groups of 30 patients each who underwent contrast-enhanced cardiac scans on a Discovery CT750 HD scanner. Group A received 270 mg I/mL iodixanol, and group B received 320 mg I/mL iodixanol contrast media and was scanned with prospective ECG triggering mode. Group C received 320 mg I/mL iodixanol and was scanned with conventional retrospective ECG gating mode. The same weight-based contrast injection protocol was used for all three groups. Images were reconstructed using a 30% adaptive statistical iterative reconstruction (ASIR) algorithm and a 50% ASIR in groups A and B and a 30% ASIR in group C. The subjective and objective image quality evaluations, diagnostic accuracies, radiation doses and amounts of contrast media in the three groups were measured and compared. RESULTS:All images in the three groups met the diagnostic requirements, with the same diagnostic accuracy and image quality scores greater than 3 in a 4-point scoring system. However, ventricular enhancement and the objective noise, signal-to-noise ratio, contrast-to-noise ratio and subjective image quality scores in group C were better than those in groups A and B (all P<.001). The effective radiation dose in groups A and B was 84% lower than that in group C (P<.001); group A received the lowest contrast dose (14% lower than that of groups B and C). CONCLUSION:Enhanced CT scan images with low dose radiation and low concentration contrast media can meet the diagnostic requirements for examining children with congenital heart disease while reducing the potential risk of radiation damage and contrast-induced nephropathy.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Liu Z,Song L,Yu T,Gao J,Zhang Q,Jiang L,Liu Y,Peng Ydoi
10.1111/ijcp.12857subject
Has Abstractpub_date
2016-09-01 00:00:00pages
B22-8eissn
1368-5031issn
1742-1241journal_volume
70 Suppl 9Bpub_type
杂志文章,随机对照试验abstract:AIMS:Studies of antimuscarinics for overactive bladder (OAB) typically use objective and subjective measures to assess efficacy, as each provides unique information about patient outcome. We evaluated the relationships between changes in diary-documented OAB symptoms and other patient-reported outcome (PRO) measures. ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
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abstract:PURPOSE:Whilst core curricula in neurology are nationally standardised, in real-world clinical practice, different approaches may be taken by individual consultants. The aims of this study were to investigate differences by assessing: (a) variance in diagnostic and investigative practice, using a case-based analysis of...
journal_title:International journal of clinical practice
pub_type: 杂志文章
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2012.02942.x
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
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更新日期:2020-10-24 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01538.x
更新日期:2007-10-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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更新日期:2011-09-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02183.x
更新日期:2009-10-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13890
更新日期:2020-12-05 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12245
更新日期:2014-03-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13389
更新日期:2019-10-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1368-5031.2004.00151.x
更新日期:2004-03-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1368-5031.2004.00182.x
更新日期:2004-06-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2002-01-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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更新日期:1998-09-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::We present one of the rarer causes of pregnancy-associated jaundice in the immediate puerperium. A 30-year-old multipara with pyruvate kinase deficiency became jaundiced within a few hours of delivery, following an uneventful pregnancy and labour at term. She responded to conservative management, the jaundice clearing...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2007-11-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
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更新日期:2010-10-01 00:00:00