The old but reliable digitalis: persistent concerns and expanded indications.

Abstract:

:Digitalis has been an old but reliable drug for 240 years. Concerns regarding its clinical indications and benefits still exist in the absence of a reduction in all-cause mortality. While intravenous digitalis is used without question in cases of atrial fibrillation, it is still controversial in sinus rhythm, despite the Digitalis Investigation Group (DIG) study showing a significant reduction in death and the need for hospitalisation for congestive heart failure in both diastolic and systolic dysfunction. The influence of digitalis in acute myocardial infarction, coronary artery disease and sudden cardiac death remains speculative. In cases of uncomplicated hypertension, it appears to prevent the onset of left ventricular dysfunction and myocardial infarction. Thus, digitalis can be a cost-effective agent with added benefits.

journal_name

Int J Clin Pract

authors

Abarquez RF Jr

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

108-14

issue

2

eissn

1368-5031

issn

1742-1241

journal_volume

55

pub_type

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