Efficacy and tolerability of candesartan cilexetil vs. amlodipine as assessed by home blood pressure in hypertensive patients.

abstract：:Non-small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It is predominantly a disease of the elderly with the median age at diagnosis 68 years. Unfortunately, the majority of patients present with advanced disease whereby palliation is the primary aim of treatment. The elderly have a lo...

journal_title：International journal of clinical practice

authors： Cheong KA,Chrystal K,Harper PG

更新日期：2006-03-01 00:00:00

abstract：:The aim of thromboprophylaxis is to minimise the incidence of clinically relevant venous thromboembolism (VTE) but in many trials designed to determine the efficacy of thromboprophylactic agents, asymptomatic VTE is included in the primary endpoint. Since asymptomatic events occur much more frequently than symptomatic...

journal_title：International journal of clinical practice

authors： Lalourcey L

更新日期：2003-05-01 00:00:00

abstract：:To investigate ethnic differences and the effect of age and education on awareness and attitudes of women towards hormone replacement therapy (HRT), we conducted a questionnaire survey of 180 women attending a gynaecology clinic, of whom 152 (84.4%) responded. Seventy-one of the women had heard of HRT. Awareness of HR...

journal_title：International journal of clinical practice

authors： Lydakis C,Kerr H,Hutchings K,Lip GY

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The regular use of simple analgesics in addition to opioids such as paracetamol (or acetaminophen) is recommended for persistent pain to enhance analgesia. Few studies have examined the frequency and doses of paracetamol among people with chronic non-cancer pain including use above the recommended maximum da...

journal_title：International journal of clinical practice

authors： Hoban B,Larance B,Gisev N,Nielsen S,Cohen M,Bruno R,Shand F,Lintzeris N,Hall W,Farrell M,Degenhardt L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:There has been a dramatic increase in the incidence of immediate breast reconstruction after mastectomy for breast cancer over the past few decades and autologous tissue flaps are being used with increasing frequency. Concern has been expressed that these complex procedures may lead to a delay in the deliver...

journal_title：International journal of clinical practice

authors： Lewis RS,Kontos M

更新日期：2009-11-01 00:00:00

abstract：:A comparison was made between the accuracy of Ames and Boehringer reagent strips for detecting urinary tract infections in 100 elderly patients (50 acutely ill patients admitted to hospital and 50 attending the day hospital). The results for urinary nitrite, blood and protein for both strips were documented. Nitrite p...

journal_title：International journal of clinical practice

authors： Evans PJ,McNabb WR,Lewis RR

更新日期：1997-10-01 00:00:00

abstract：AIMS:To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments. METHODS:Published papers related to the mechanism of action of approved osteoporosis treatments were sought through MEDLINE searches. FINDINGS:Osteoporot...

journal_title：International journal of clinical practice

authors： Hanley DA,Adachi JD,Bell A,Brown V

更新日期：2012-12-01 00:00:00

abstract：:Twenty cases of tuberculous meningitis were diagnosed at the Hamad Medical Corporation between 1990 and 1995. Most of the patients (90%) were expatriates. The most common presenting features were fever, headache, neck stiffness and altered mental status. Five patients were in stage 1 disease at the time of presentatio...

journal_title：International journal of clinical practice

authors： Alsoub H

更新日期：1998-07-01 00:00:00

abstract：:Gastrointestinal tract (GIT) foreign bodies represent a significant clinical problem in the Emergency Department, causing a high degree of financial burden, morbidity and mortality. A large variety of foreign bodies are accidentally ingested or inserted into the GIT in different age groups. This a retrospective review...

journal_title：International journal of clinical practice

authors： Ayantunde AA,Oke T

更新日期：2006-06-01 00:00:00

abstract：:A 60-year-old man noticed rapid enlargement of a long-standing thyroid goitre, with dysphagia and difficulty in breathing. Thyrotoxicosis was diagnosed. Chest X-ray revealed multiple pulmonary metastases. He underwent near-total thyroidectomy. The histopathology revealed an undifferentiated thyroid carcinoma with some...

journal_title：International journal of clinical practice

authors： Plengvidhya N,Rathanavijitrasilp A,Sangruchi T,Nitiyanant W,Vannasaeng S,Piraphatdist T,Vichayanrat A

更新日期：1997-10-01 00:00:00

abstract：AIMS:We prospectively enrolled 207 patients (121 were 75 or older and 86 younger than 75) who were admitted to three Respiratory Monitoring Units. The primary outcomes were intubation and mortality rates; the secondary outcomes were changes in arterial blood gases analysis, non-invasive ventilation (NIV) duration and l...

journal_title：International journal of clinical practice

authors： Nicolini A,Santo M,Ferrera L,Ferrari-Bravo M,Barlascini C,Perazzo A

更新日期：2014-12-01 00:00:00

abstract：AIM:We analysed the effectiveness and safety of outpatient parenteral antibiotic therapy (OPAT) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in patients admitted to home hospitalisation units (HHU). METHODS:Retrospective multicentre study of patients with AECOPD included in the Spanish OPAT ...

journal_title：International journal of clinical practice

authors： Ponce González MA,Mirón Rubio M,Mujal Martinez A,Estrada Cuxart O,Fiuza Perez D,Salas Reinoso L,Fernández Fabrellas E,Chiner Vives E

更新日期：2017-12-01 00:00:00

abstract：:'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...

journal_title：International journal of clinical practice

authors： Fava GA,Tomba E,Sonino N

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In 2006, the American Diabetes Association and the European Association for the Study of Diabetes established a consensus algorithm (ADA/EASD-2006) for the adjustment of drug therapy for type 2 diabetes mellitus (T2DM). AIMS:To study glycaemic control in T2DM patients and the implementation of the ADA/EASD-...

journal_title：International journal of clinical practice

authors： Alvarez-Guisasola F,Guiada Study Group.

更新日期：2014-01-01 00:00:00

abstract：:A case of alexia without agraphia is presented. It is a rare but classic disconnection syndrome, first described by Dejerine in 1892. Recent advances in modern neuroimaging techniques such as FLAIR MRI can now localise in vivo the site of origin of the syndrome, especially when computerised axial tomogram of the brain...

journal_title：International journal of clinical practice

authors： Imtiaz KE,Nirodi G,Khaleeli AA

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Although the relationship of elevated serum uric acid levels and cardiovascular disease has been established in a great number of studies, the causal relevance of this finding remains ambiguous. An approach to evaluate the causal relevance of biomarkers is to exploit the natural randomised allocation of alle...

journal_title：International journal of clinical practice

authors： Kei A,Koutsouka F,Makri A,Elisaf M

更新日期：2018-01-01 00:00:00

abstract：AIMS:This investigation determined the proportion of adults newly diagnosed as having type-2 diabetes mellitus (T2DM), and ascertained risk predictors for development of self-reported T2DM. METHODS:The US Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD) survey was a 5-...

journal_title：International journal of clinical practice

authors： Rodbard HW,Bays HE,Gavin JR 3rd,Green AJ,Bazata DD,Lewis SJ,Fox KM,Reed ML,Grandy S

更新日期：2012-07-01 00:00:00

abstract：AIMS:To validate a previously developed set of explicit criteria for the appropriateness of hospital admission among these patients using the RAND/UCLA Appropriateness Methodology (RAM). METHODS:We conducted a prospective cohort study of patients experiencing symptoms of COPD exacerbation seen in the emergency departm...

journal_title：International journal of clinical practice

authors： Garcia-Gutierrez S,Quintana JM,Bilbao A,Unzurrunzaga A,Esteban C,Baré M,Girón Moreno RM,Pulido E,Rivas P,IRYSS-COPD Appropriateness Study (IRYSS-COPD) Group.

更新日期：2014-07-01 00:00:00

abstract：:Nisoldipine coat-core (nisoldipine CC), an extended-release once-daily formulation, is an effective treatment for mild-to-moderate hypertension, providing sustained blood pressure control over the 24-hour dosing interval. Nisoldipine CC is highly vascular selective. It causes neither reflex tachycardia nor symptomatic...

journal_title：International journal of clinical practice

authors： Zannad F

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Serum sodium overcorrection and hypernatremia are significant health risks. We conducted a systematic review and meta-analysis to evaluate the risks of vaptans in hypernatremia and serum sodium overcorrection. METHODS:We searched PubMed, Embase, and CENTRAL for randomised controlled trials. We included studi...

journal_title：International journal of clinical practice

authors： Zhou Y,Yang W,Liu G,Gao W

更新日期：2020-12-17 00:00:00

abstract：INTRODUCTION:Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD. OBJECTIVE:To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population ...

journal_title：International journal of clinical practice

authors： Herráiz-Adillo Á,Piñar-Serrano O,Mariana-Herráiz JÁ,Martínez-Vizcaíno V,Pozuelo-Carrascosa DP,Notario-Pacheco B

更新日期：2018-11-01 00:00:00

abstract：:Leptospirosis is a re-emerging spirochetal zoonosis with a worldwide distribution affecting both animals and humans. The clinical syndromes may vary from a subclinical infection to a severe illness. Although it may potentially have a fulminant and fatal course, leptospirosis usually remains as an underdiagnosed cause ...

journal_title：International journal of clinical practice

authors： Dursun B,Bostan F,Artac M,Varan HI,Suleymanlar G

更新日期：2007-01-01 00:00:00

abstract：:In 2006 Meiron Thomas, writing in the British Journal of Surgery, made the following statement about the value of sentinel lymph node biopsy (SLNB) as a staging procedure in cutaneous malignant melanoma (1): "Perhaps a more important concern for those hoping to gain reassurance from accurate nodal staging relates to p...

journal_title：International journal of clinical practice

authors： Russell-Jones R

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Vardenafil has demonstrated efficacy for the pharmacological management of erectile dysfunction (ED). Accumulating evidence suggests that ED is frequently associated with underlying cardiovascular and metabolic conditions which are thought to be involved in the aetiology of ED. The present review aims to summ...

journal_title：International journal of clinical practice

authors： Eardley I,Lee JC,Guay AT

更新日期：2008-10-01 00:00:00

abstract：:Amyloidosis commonly involves the liver but clinical features of liver disease are rare. We report a case of cholestasis and hepatic failure in an 85-year-old man due to primary amyloidosis. This has not been reported previously in anyone of this advanced age. We discuss the clinical features of hepatic amyloidosis an...

journal_title：International journal of clinical practice

authors： McDonald P,Usbourne C,Playfer JR

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate the relationship between the use of medicinal plants and medication adherence in elderly people. METHODS:Observational, cross-sectional study of elderly residents in Cuité-PB, Northeastern Brazil, through a household survey. A stratified proportional and systema...

journal_title：International journal of clinical practice

authors： Martins RR,Duarte Farias A,Russel Martins R,Gouveia Oliveira A

更新日期：2016-03-01 00:00:00

abstract：AIMS:Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out 6 years earli...

journal_title：International journal of clinical practice

authors： Molero JM,Moragas A,González López-Valcárcel B,Bjerrum L,Cots JM,Llor C

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:The ENDURANCE study evaluated the efficacy of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, in men with erectile dysfunction (ED), by measuring the duration of erection leading to successful intercourse using a stopwatch as the assessment instrument. METHODS:This was a randomised, multicentre, dou...

journal_title：International journal of clinical practice

authors： Rosenberg MT,Adams PL,McBride TA,Roberts JN,McCallum SW

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:We aimed to investigate the effect of a low-protein intake on all-cause mortality in subjects with an estimated glomerular filtration rate (eGFR) ≧60 mL/min/1.73 m2 with or without albuminuria using data from the National Health and Nutrition Examination Survey (NHANES). METHODS:We analysed participants in ...

journal_title：International journal of clinical practice

authors： Lee CL,Liu WJ,Wang JS

更新日期：2020-07-01 00:00:00

abstract：:Asthma treatment is suboptimal in many patients, with impacts on morbidity and mortality, healthcare resource utilisation and patients' quality of life. The reasons for this include the inherent variability of asthma and the unpredictability of exacerbations, which can range from mild to fatal. In addition, asthma can...

journal_title：International journal of clinical practice

authors： Gillissen A

更新日期：2004-06-01 00:00:00