Abstract:
:Twenty cases of tuberculous meningitis were diagnosed at the Hamad Medical Corporation between 1990 and 1995. Most of the patients (90%) were expatriates. The most common presenting features were fever, headache, neck stiffness and altered mental status. Five patients were in stage 1 disease at the time of presentation, 11 in stage 2, and four in stage 3. Examination of cerebrospinal fluid showed at least one abnormal finding in all patients, and culture grew Mycobacterium tuberculosis in 50%. A positive tuberculin skin test in 50% of patients, abnormal chest X-ray in 35%, abnormal CT scan or MRI showing tuberculoma or hydrocephalus in 55%, and positive sputum culture for M. tuberculosis in 15% helped establish the diagnosis. All the patients were treated with antituberculous drugs and steroids. Seventeen (85%) survived, three with severe neurological sequelae; three (15%) died. Poor outcome was associated with advanced stage of disease at presentation and high CSF protein. Tuberculous meningitis continues to be an important disease in Qatar, especially in expatriates, and should be considered in the differential diagnosis in any patient presenting with fever and change in sensorium.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Alsoub Hsubject
Has Abstractpub_date
1998-07-01 00:00:00pages
300-4issue
5eissn
1368-5031issn
1742-1241journal_volume
52pub_type
杂志文章abstract::Biochemical test abnormality can indicate chronic alcohol abuse with good clinical sensitivity and specificity. Serum gamma glutamyltransferase and carbohydrate-deficient transferrin are the tests most frequently abnormal. ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
abstract::It is important for primary care physicians to recognise rheumatoid arthritis and systemic lupus erythematosus patients as high-risk groups for atherosclerosis, requiring aggressive risk-factor modification. Recent studies suggest that this increased risk is not explained by an excess of traditional risk factors, but ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2005.00489.x
更新日期:2005-07-01 00:00:00
abstract::Current therapy in Russia for long-term management of asthma is mainly non-steroidal. This provided the opportunity to compare the efficacy and safety of formoterol (Oxis) Turbuhaler plus budesonide (Pulmicort) Turbuhaler with budesonide Turbuhaler alone in adults (n=338) with mild to moderate asthma who had little pr...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2002-01-01 00:00:00
abstract::Cystic fibrosis (CF) is one of the commonest lethal inherited conditions among Caucasians. It affects multiple organ systems and exhibits a range of clinical problems of varying severity. Life expectancy has improved in recent years as treatment regimes have become more intensive, but current treatments are expensive,...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2000-04-01 00:00:00
abstract::In this review, we discuss right-sided heart valve disease, namely tricuspid regurgitation (TR), tricuspid stenosis, pulmonary regurgitation, pulmonary stenosis and right-sided endocarditis. These are frequently seen in conjunction with other diseases, making assessment of their significance more difficult, but it has...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12485
更新日期:2014-10-01 00:00:00
abstract::The aim of this study was to audit the preoperative administration of regular cardiac medication in general surgical patients and to determine if this can be improved with simple ward-based education. The notes and drug charts of 102 general surgical adult inpatients undergoing elective operations were analysed prospe...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01002.x
更新日期:2006-10-01 00:00:00
abstract::Hepatic endometriosis is extremely rare. The diagnosis is often missed and treatment is delayed. A 37-year-old woman was referred to the gynaecology department with vague abdominal pains. She had a past history of pelvic endometriosis and hysterectomy with bilateral salpingo-oophorectomy. Further investigations in due...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::A 62-year-old man presented with a five-day history of a 'flu-like' illness, epigastric pain and a state of increasing confusion. His serum values for amylase and glucose were grossly elevated, as was the creatine kinase (CK) activity, being 23 times above the upper limit of normal. CK-MB was less than 5% of his total...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::In this journal, Cummins et al reported an experiment that examined clinicians' predictions of causes of death from subjects' pre-morbid photographs. They found that clinicians performed at chance. The validity of two of their other conclusions are challenged. First, that clinicians routinely form impressions of how a...
journal_title:International journal of clinical practice
pub_type: 评论,杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::Hypogonadism may play a significant role in the pathophysiology of erectile dysfunction (ED). A threshold level of testosterone may be necessary for normal erectile function. Testosterone replacement therapy is indicated in hypogonadal patients and is beneficial in patients with ED and hypogonadism. Monotherapy with t...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2006.01101.x
更新日期:2006-09-01 00:00:00
abstract::Patients presenting to the emergency department with chest pain are evaluated by emergency physicians in hospitals without cardiology cover 24 h a day. The purpose of this study is to determine the consistency of electrocardiography (ECG) interpretation and chest pain likelihood classification between emergency physic...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-1241.2005.00788.x
更新日期:2006-10-01 00:00:00
abstract::Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current tr...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12471
更新日期:2014-10-01 00:00:00
abstract::We reviewed the results of 22 operations performed on 21 patients for the relief of de Quervain's disease over the last six years. At a mean follow-up of 34 months (range 4-78 months), 18 of 22 wrists had complete relief of their original symptoms. One patient required reoperation because of inadequate decompression, ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::This open multicentre study compared the efficacy and tolerability of clarithromycin and spiramycin in the treatment of lower respiratory tract infections in Brazil and Colombia. A total of 125 patients with a clinical and radiological diagnosis of pneumonia, acute bronchitis or exacerbation of chronic bronchitis were...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1999-09-01 00:00:00
abstract::Cases of transient global amnesia (TGA) seen by one consultant neurologist over a 4-year period (2002-2005 inclusive) were identified. Of 10 possible cases, eight fulfilled suggested diagnostic criteria. Five cases were seen as ward consultations, three in outpatient clinics; seven were seen in district general hospit...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.00897.x
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Plasminogen Activator Inhibitor 1 (PAI-1) is a prothrombotic adipokine involved in the coagulation cascade and fibrinolysis that associated with proinflammatory adipokines may increase the risk related to obesity. Anthropometric measures are commonly used in clinical practice and, currently, neck circumferen...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12041
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The regular use of simple analgesics in addition to opioids such as paracetamol (or acetaminophen) is recommended for persistent pain to enhance analgesia. Few studies have examined the frequency and doses of paracetamol among people with chronic non-cancer pain including use above the recommended maximum da...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12716
更新日期:2015-11-01 00:00:00
abstract::Ranitidine is one of the widely prescribed H2 receptor antagonists in the treatment of peptic ulcer. It is well tolerated and has few side-effects. Vasculitic rash occurring in association with ranitidine has been described. We report a case of a 39-year-old man who developed a purpuric rash, polyarthritis, abdominal ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Antibiotics are widely used and inaccurate or inappropriate prescription of antibiotics causes a significant increase in the prevalence of multidrug-resistant bacterial infections among children. This research aimed to study antibiotic prescriptions in hospitalised paediatric patients and to determine the pr...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13782
更新日期:2020-10-24 00:00:00
abstract::People with genuine anxiety disorders can be misdiagnosed and mismanaged, because of negative public and professional attitudes to anxiety and the 'worried well'. Misdiagnosis includes not taking symptoms seriously and giving patients pejorative labels such as 'personality disorder' or 'inadequate'. This can lead to m...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.00998.x
更新日期:2007-08-01 00:00:00
abstract:AIMS:To demonstrate the benefit of the combination amlodipine/valsartan 5/160 mg over amlodipine 10 mg, in producing a lower incidence of peripheral oedema for a comparable mean sitting systolic blood pressure (MSSBP) reduction. METHODS:After a 4-week amlodipine 5 mg run-in phase, inadequately controlled hypertension ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2008.01977.x
更新日期:2009-02-01 00:00:00
abstract:AIM:This study aimed to determine the impact of long-term treatment with continuous positive airway pressure (CPAP) and obstruction relieving surgical procedure on obstructive sleep apnoea syndrome (OSAS) patients on erectile function (EF). METHODS:Eighty male OSAS patients, suffering from erectile dysfunction (ED) we...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2012.02990.x
更新日期:2012-12-01 00:00:00
abstract::Indiplon is a novel non-benzodiazepine sedative-hypnotic that modulates the GABAA receptor complex. It appears to be more selective for the alpha1-receptor subunit, associated with sedation, than other hypnotics. Two different formulations of indiplon have been developed: an immediate release (IR) version targeting sl...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01322.x
更新日期:2007-06-01 00:00:00
abstract::The phenomenon of spontaneous remission is one of the less well known aspects of the leukaemias. Spontaneous remission has been reported in both acute and chronic leukaemia. The mechanism is unclear but may involve immune modulation related to an intercurrent infection or transfusion of blood products. We present a ra...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract:AIM:Risk stratification in acute coronary syndrome without ST-segment elevation (NSTE-ACS) and troponin-negative remains a challenge. We evaluated the value of interleukin-6 (IL-6) and amino-terminal pro-B-type natriuretic peptide (NT-proBNP) in the prognosis assessment of low-moderate risk NSTE-ACS and troponin-negati...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12245
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Ultrasonography is increasingly used by clinicians to identify abdominal aortic aneurysms (AAA). We performed a systematic review and meta-analysis comparing the accuracy of non-radiologist performed ultrasound (NRPUS) for AAA disease to the 'gold standard' of radiologist performed aortic imaging (RPI), intr...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ijcp.12453
更新日期:2014-09-01 00:00:00
abstract::A 43-year-old female patient with Basedow-Graves' disease developed agranulocytosis in the eighth month of propylthiouracil therapy. After discontinuing the drug, a broad spectrum antibiotic regimen plus recombinant human granulocyte colony-stimulating factor (G-CSF), a human haematopoietic growth factor, were started...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION:Patients with atrial fibrillation (AF) are more symptomatic than patients with sinus rhythm. However, it is unknown what per cent of time spent in AF is associated with symptoms. METHODS:We used a limited access dataset from the Atrial Fibrillation Follow-up Investigation of Rhythm Management trial. Patie...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12262
更新日期:2014-04-01 00:00:00
abstract::Randomised controlled trials evaluating the effect of statin use on maintenance of normal sinus rhythm (NSR) after electrical cardioversion (ECV) of persistent atrial fibrillation (AF) have demonstrated conflicting results. However, many of these trials were of relatively small size and thus underpowered to adequately...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1742-1241.2010.02387.x
更新日期:2010-07-01 00:00:00