Effectiveness and clinical inertia in patients with antidiabetic therapy.

abstract：:A high prevalence of newly detected diabetes mellitus (DM) and impaired glucose tolerance (IGT) has been reported in patients with acute myocardial infarction (AMI) and no previous diagnosis of DM. However, the prevalence of newly detected DM is grossly underestimated by using fasting plasma glucose (FPG). We determin...

journal_title：International journal of clinical practice

authors： Jessani S,Gangopadhyay K,Patel JV,Lip GY,Millane T

更新日期：2007-04-01 00:00:00

abstract：AIMS:To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments. METHODS:Published papers related to the mechanism of action of approved osteoporosis treatments were sought through MEDLINE searches. FINDINGS:Osteoporot...

journal_title：International journal of clinical practice

authors： Hanley DA,Adachi JD,Bell A,Brown V

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Substantial residual cardiovascular risk persists despite effective LDL lowering treatment in populations at elevated risk for adverse cardiovascular outcomes. Low HDL cholesterol is an independent cardiovascular risk factor and occurs in about one-third of patients treated for dyslipidaemia in Europe. Moreo...

journal_title：International journal of clinical practice

authors： Vogt A,Kassner U,Hostalek U,Steinhagen-Thiessen E

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the Joint British Societies' (JBS 2) Factfile, cardiovascular risk assessment paper charts and electronic risk calculator posted to health professionals in general practice. DESIGN:Phase one: surveys on use of the JBS 2 charts and calculator; views on improving use and ...

journal_title：International journal of clinical practice

authors： Kirby M,Machen I

更新日期：2009-12-01 00:00:00

abstract：AIM:The aim of this study was to investigate how patients' expectations about and experiences with insulin therapy contribute to diabetes treatment satisfaction. METHODS:The Expectations about Insulin Therapy (EAITQ) and the Experience with Insulin Therapy Questionnaires (EWITQ) were administered at baseline and end-p...

journal_title：International journal of clinical practice

authors： Naegeli AN,Hayes RP

更新日期：2010-06-01 00:00:00

abstract：:We report a humeral fracture associated with complete radial nerve palsy, where immediate nerve recovery followed decompression. This uncommon type of nerve lesion is referred to as axonamonosis and is not included in the traditional Seddon nerve injury classification. ...

journal_title：International journal of clinical practice

authors： Marsh AJ,Singh B,Iossifidis A

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To explore the association between illicit drug use (IDU) and cardiometabolic disease risk factors (CDRF) in a nationally representative sample of adults. METHODS:The 2005-2008 National Health and Nutrition Examination Surveys data from 20- to 45-year-old adults (n = 8738) were utilised to analyze the relation...

journal_title：International journal of clinical practice

authors： Vidot DC,Arheart KL,Prado G,Bandstra ES,Messiah SE

更新日期：2013-11-01 00:00:00

abstract：:This meta-analysis was undertaken to compare the effects of succinylcholine (SCH) and rocuronium (RCR) on endotracheal intubation (ETI) conditions. Eligible randomised controlled trials (RCTs) were identified via medline and a manual search of references. The frequencies of excellent and unacceptable ETI conditions in...

journal_title：International journal of clinical practice

authors： Karcioglu O,Arnold J,Topacoglu H,Ozucelik DN,Kiran S,Sonmez N

更新日期：2006-12-01 00:00:00

abstract：:Despite differences in design, many large epidemiological studies using well-powered multivariate analyses consistently provide overwhelming evidence of a link between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Preclinical evidence suggests that several common pathophysiological mechanisms are ...

journal_title：International journal of clinical practice

authors： Kirby M,Chapple C,Jackson G,Eardley I,Edwards D,Hackett G,Ralph D,Rees J,Speakman M,Spinks J,Wylie K

更新日期：2013-07-01 00:00:00

abstract：:Fracture of the penis can be managed conservatively or surgically. Conservative management is associated with a high morbidity, and early surgical repair of the fracture is usually recommended in order to prevent complications. Because a fractured penis is swollen throughout its length, it is difficult to identify the...

journal_title：International journal of clinical practice

authors： Naraynsingh V,Ramdass MJ,Thomas D,Maharaj D

更新日期：2003-06-01 00:00:00

abstract：:The efficacy of prophylactic carboxymethylcellulose (CMC) in reducing the time to reach full enteral feeds (FEFs) in neonates <32 weeks' gestation was studied in a clinical trial. When ready for feeds, enrolled neonates were allocated to either CMC (dose: CMC content of 12 mg oral erythromycin ethyl succinate syrup, 6...

journal_title：International journal of clinical practice

authors： Patole SK,Muller R

更新日期：2005-05-01 00:00:00

abstract：:Some chiropractors claim that spinal manipulation is an effective treatment for infant colic. This systematic review was aimed at evaluating the evidence for this claim. Four databases were searched and three randomised clinical trials met all the inclusion criteria. The totality of this evidence fails to demonstrate ...

journal_title：International journal of clinical practice

authors： Ernst E

更新日期：2009-09-01 00:00:00

abstract：:We report an unusual presentation of non-Hodgkin's lymphoma of the thyroid which mimicked an acute infective thyroiditis and was associated with acute stridor and dysphagia. The mode of presentation and diagnosis of thyroid lymphoma are discussed and the value of early fine needle aspiration emphasised. ...

journal_title：International journal of clinical practice

authors： Arullendran P,Pfleiderer AG

更新日期：1998-11-01 00:00:00

abstract：AIM:Splenectomised patients are associated with lifelong risk of fatal overwhelming post-splenectomy infection (OPSI), which is mostly caused by Streptococcus pneumoniae. Today OPSI cases can still be reported even in patients with appropriate vaccination. In our study, the levels of vaccine-specific memory B- and T ce...

journal_title：International journal of clinical practice

authors： Gazi U,Karasartova D,Sahiner IT,Gureser AS,Tosun O,Derici MK,Dolapci M,Taylan Ozkan A

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Cardiovascular medications are effective in prevention of cardiovascular diseases (CVD); however, medication non-adherence contributes to morbidity and mortality. OBJECTIVE:This systematic review and meta-analysis aims to summarise the evidence regarding the relationship between characteristics of drug th...

journal_title：International journal of clinical practice

authors： Schneider APH,Gaedke MÂ,Garcez A,Barcellos NT,Paniz VMV

更新日期：2018-01-01 00:00:00

abstract：:General practitioners (GPs) are increasingly involved in the selective opportunistic case finding of osteoporosis and treatment of this condition. An open access bone densitometry service has existed for GPs in the Cardiff area since 1993. The purpose of this study was to assess the effectiveness of this service, part...

journal_title：International journal of clinical practice

authors： Sim MF,Stone M,Johansen A,Ho P,Pettit RJ,Evans WD

更新日期：2004-03-01 00:00:00

abstract：:Manifestations of atypical gastroesophageal reflux disease (GORD) are varied, and the presentation of atypical symptoms may occur in the absence of typical symptoms. The most sensitive and specific investigation for GORD is pH monitoring, and its application in atypical disease is utilized throughout this paper as a b...

journal_title：International journal of clinical practice

authors： Chandra A,Moazzez R,Bartlett D,Anggiansah A,Owen WJ

更新日期：2004-01-01 00:00:00

abstract：AIMS:To examine whether the blood pressure (BP) profiles of lumiracoxib and high-dose ibuprofen differed in patients treated with different classes of antihypertensive medications. METHODS:A 4-week, multicentre, randomised, double-blind study has compared the effects of lumiracoxib 100 mg once daily (od) (n = 394) and...

journal_title：International journal of clinical practice

authors： MacDonald TM,Richard D,Lheritier K,Krammer G

更新日期：2010-05-01 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a nerve entrapment disorder, involving the median nerve when it passes the carpal tunnel at the wrist. Using a case-control methodology, 312 electrophysiologically confirmed CTS patients with mean age of 51.3+/-9.4 (27-74) years (81.7% women) and 100 controls with mean age of 50.4+/-9.2...

journal_title：International journal of clinical practice

authors： Tan EK,Koh KK,Arulanandam S,Lo YL

更新日期：2004-11-01 00:00:00

abstract：:Of the 25,000 new cases of breast cancer annually in the UK, at least half will develop metastases at some time. Approximately one-third of these will be hormone-sensitive and thus suitable for endocrine manipulation. Such patients may live for several years. Care should be patient-centred and evidence-based, with pri...

journal_title：International journal of clinical practice

authors： Theobald AJ

更新日期：2000-12-01 00:00:00

abstract：:We reviewed the results of 22 operations performed on 21 patients for the relief of de Quervain's disease over the last six years. At a mean follow-up of 34 months (range 4-78 months), 18 of 22 wrists had complete relief of their original symptoms. One patient required reoperation because of inadequate decompression, ...

journal_title：International journal of clinical practice

authors： Mellor SJ,Ferris BD

更新日期：2000-03-01 00:00:00

abstract：:The aim of this study was to audit the preoperative administration of regular cardiac medication in general surgical patients and to determine if this can be improved with simple ward-based education. The notes and drug charts of 102 general surgical adult inpatients undergoing elective operations were analysed prospe...

journal_title：International journal of clinical practice

authors： Corfield LF,Trivedi PM,Wilson D

更新日期：2006-10-01 00:00:00

abstract：AIM:To assess the efficacy and safety of dipeptidyl peptidase 4-inhibitors (DPP4-I) compared with sulphonylureas in adults with type 2 diabetes (T2D) mellitus. METHOD:Randomised controlled trials were collected from PubMed, EMBASE, Google Scholar and conference. The primary outcome was the change in HbA1c. Secondary o...

journal_title：International journal of clinical practice

authors： Zhou JB,Bai L,Wang Y,Yang JK

更新日期：2016-02-01 00:00:00

abstract：AIMS:There is evidence suggesting that the respiratory response to sedation is different in patients with sleep apnoea, which is common in patients with chronic renal failure (CRF). This study examined the respiratory response of sedation with propofol and alfentanil, whose pharmacokinetics are not affected by the rena...

journal_title：International journal of clinical practice

authors： Lee SM,Kim GH,Lee JJ,Kim JA,Choi SJ,Kim GS,Jung HH

更新日期：2010-01-01 00:00:00

abstract：:Omalizumab, a recombinant, humanised monoclonal antibody against human IgE, will be introduced soon for the treatment of allergic asthma. This antibody binds circulating IgE molecules and inhibits the type I immune response in the lung and other target organs. In the phase II and III studies performed, it demonstrated...

journal_title：International journal of clinical practice

authors： Solèr M

更新日期：2001-09-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of adult blindness among individuals aged 50 and older in the Western world, with the neovascular form of AMD responsible for the most severe and rapid visual loss. Although monotherapy with currently available treatments can slow the rate of loss of vision i...

journal_title：International journal of clinical practice

authors： Kaiser PK,Do DV

更新日期：2007-03-01 00:00:00

abstract：:This case report describes a patient who presented with pyrexia of unknown origin allied with hypertriglyceridaemia (16.2 mmol/l) but not hypercholesterolaemia (4.1 mmol/l). Investigations identified the cause of the pyrexia as an adult T-cell lymphoma of natural killer cell phenotype (CD3[+], CD7[+], anti-TCR alpha/b...

journal_title：International journal of clinical practice

authors： Suryanarayanan S,Wierzbicki AS,Carr R,Ritter JM

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To describe the efficacy and safety of asenapine for the treatment of schizophrenia and bipolar disorder. DATA SOURCES:The pivotal registration trials were accessed by querying http://www.pubmed.gov, http://www.fda.gov and http://www.clinicaltrials.govfor the search terms 'asenapine' or 'ORG 5222'. STUDY SE...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2009-12-01 00:00:00

abstract：:Despite efforts to diagnose and treat hypertension effectively, the goal of lowering blood pressure (BP) levels is rarely achieved, as treatment is often initiated with a single antihypertensive agent. The aim of this study was to assess the safety and efficacy of a first-line fixed-dose combination treatment compared...

journal_title：International journal of clinical practice

authors： Scholze J,Bida M,Hansen A,Juncken D,Rangoonwala B,Ritz A,Schnitker J,Dörffel Y

更新日期：2006-03-01 00:00:00

abstract：AIMS:Arterial hypertension is a well-established factor for increased risk of cardiovascular diseases, but low admission blood pressure has also been suggested as predictor for increased mortality. We hypothesised that in patients with acute myocardial infarction admission blood pressure at the Emergency Department pre...

journal_title：International journal of clinical practice

authors： Roth D,Van Tulder R,Heidinger B,Herkner H,Schreiber W,Havel C

更新日期：2015-08-01 00:00:00