Omalizumab, a monoclonal antibody against IgE for the treatment of allergic diseases.

abstract：:In this review, we discuss right-sided heart valve disease, namely tricuspid regurgitation (TR), tricuspid stenosis, pulmonary regurgitation, pulmonary stenosis and right-sided endocarditis. These are frequently seen in conjunction with other diseases, making assessment of their significance more difficult, but it has...

journal_title：International journal of clinical practice

authors： Coffey S,Rayner J,Newton J,Prendergast BD

更新日期：2014-10-01 00:00:00

abstract：AIMS:To evaluate in a real-world setting the effectiveness of exenatide once-weekly (ExQW) in patients with T2D and to determine predictors of glycaemic and weight response to this drug at 6 months. METHODS:Observational, retrospective, multicenter study in adult patients with T2D and BMI ≥30 kg/m2 from 4 tertiary Spa...

journal_title：International journal of clinical practice

authors： Gorgojo-Martínez JJ,Gargallo-Fernández MA,Brito-Sanfiel M,Lisbona-Catalán A

更新日期：2018-03-01 00:00:00

abstract：AIMS:To validate a previously developed set of explicit criteria for the appropriateness of hospital admission among these patients using the RAND/UCLA Appropriateness Methodology (RAM). METHODS:We conducted a prospective cohort study of patients experiencing symptoms of COPD exacerbation seen in the emergency departm...

journal_title：International journal of clinical practice

authors： Garcia-Gutierrez S,Quintana JM,Bilbao A,Unzurrunzaga A,Esteban C,Baré M,Girón Moreno RM,Pulido E,Rivas P,IRYSS-COPD Appropriateness Study (IRYSS-COPD) Group.

更新日期：2014-07-01 00:00:00

abstract：:In a previous report the effectiveness of intraperitoneal bupivacaine in reducing pain following laparoscopic cholecystectomy was demonstrated. Other methods of pain relief are commonly used but none has been compared following laparoscopic cholecystectomy. In two further studies we have compared the analgesic effect ...

journal_title：International journal of clinical practice

authors： Johnson RC,Hedges AR,Morris R,Stamatakis JD

更新日期：1999-01-01 00:00:00

abstract：AIMS:To evaluate the efficacy of switching from a previous statin monotherapy to ezetimibe/simvastatin (EZE/SIMVA) 10/20 mg vs. rosuvastatin (ROSUVA) 10 mg. METHODS:In this randomised, double-blind study, 618 patients with documented hypercholesterolaemia [low-density lipoprotein cholesterol (LDL-C) > or = 2.59 and < ...

journal_title：International journal of clinical practice

authors： Farnier M,Averna M,Missault L,Vaverkova H,Viigimaa M,Massaad R,Vandormael K,Johnson-Levonas AO,Brudi P

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Studies in the primary care setting are of high interest for assessing the management situation of patients with manifestations of atherothrombosis. AIMS:Therefore, we documented diagnostic procedures, characteristics, and management of patients with symptomatic and asymptomatic peripheral arterial disease ...

journal_title：International journal of clinical practice

authors： Kröger K,Schwertfeger M,Pittrow D,Diehm C

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, followin...

journal_title：International journal of clinical practice

authors： Jun L,Yuguo C,Zhiguo W,Jinfeng L,Huawei M,Xiuhua L,Yonggui Z,Yanhua X,Kong Y,Hongtao L,Yuliang Z

更新日期：2013-10-01 00:00:00

abstract：:Gastrointestinal tract (GIT) foreign bodies represent a significant clinical problem in the Emergency Department, causing a high degree of financial burden, morbidity and mortality. A large variety of foreign bodies are accidentally ingested or inserted into the GIT in different age groups. This a retrospective review...

journal_title：International journal of clinical practice

authors： Ayantunde AA,Oke T

更新日期：2006-06-01 00:00:00

abstract：:The current study compared the effectiveness of the graduated tuning fork (128 Hz) and the neurothesiometer in assessing vibration sensation perception in patients presenting with type II diabetes mellitus. A quota sample of patients (n = 21; age range 43-73 years) were assessed using the neurothesiometer and tuning f...

journal_title：International journal of clinical practice

authors： O'Neill J,McCann SM,Lagan KM

更新日期：2006-02-01 00:00:00

abstract：:Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current tr...

journal_title：International journal of clinical practice

authors： Rayner J,Coffey S,Newton J,Prendergast BD

更新日期：2014-10-01 00:00:00

abstract：AIMS:Little is known on factors associated with switching and combination use of antidepressants. Our aim was to describe such use and to analyse the association with socioeconomic factors and level of care in Swedish adults aged 20-34 years. METHODS:Individuals, aged 20-34 years, who purchased an antidepressant in Ja...

journal_title：International journal of clinical practice

authors： Andersson Sundell K,Petzold MG,Wallerstedt SM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Although the relationship of elevated serum uric acid levels and cardiovascular disease has been established in a great number of studies, the causal relevance of this finding remains ambiguous. An approach to evaluate the causal relevance of biomarkers is to exploit the natural randomised allocation of alle...

journal_title：International journal of clinical practice

authors： Kei A,Koutsouka F,Makri A,Elisaf M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Stroke risk is heightened among patients who have had a primary stroke or transient ischaemic attack (TIA). The primary care physician is in the best position to monitor these patients for stroke recurrence. Because stroke recurrence can occur shortly after the primary event, guidelines recommend initiating ...

journal_title：International journal of clinical practice

authors： Kirshner HS

更新日期：2007-10-01 00:00:00

abstract：:The difficulties in establishing a diagnosis of acute disseminated encephalomyelitis (ADEM) are illustrated in this case report, which attempts to raise awareness of the condition among general physicians, since they are the practitioners most likely to see such acute neurological presentations. Clinical and investiga...

journal_title：International journal of clinical practice

authors： John L,Khaleeli AA,Larner AJ

更新日期：2003-04-01 00:00:00

abstract：AIMS:To investigate the association between the self-perception period of OAB symptoms (SP-OAB) and the overactive bladder symptom score (OABSS), along with related sociodemographic and lifestyle factors. METHODS:This was a cross-sectional study comprised of 192 men aged 40 years and older who participated in a prosta...

journal_title：International journal of clinical practice

authors： Kim JH,Ham BK,Shim SR,Lee WJ,Kim HJ,Kwon SS,Bae JH

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of three non-invasive blood pressure (BP) devices in atrial fibrillation (AF) compared with invasive arterial BP. METHODS:One hundred patients aged 45-90 years, 63% male (50 in AF and 50 age matched controls in sinus rhythm [SR]) were identified with arterial lines measuring beat-...

journal_title：International journal of clinical practice

authors： Eysenck W,Ammar A,Kanthasamy V,Freemantle N,Veasey RA,Patel NR,Furniss SS,Sulke N

更新日期：2019-08-29 00:00:00

abstract：:A high prevalence of newly detected diabetes mellitus (DM) and impaired glucose tolerance (IGT) has been reported in patients with acute myocardial infarction (AMI) and no previous diagnosis of DM. However, the prevalence of newly detected DM is grossly underestimated by using fasting plasma glucose (FPG). We determin...

journal_title：International journal of clinical practice

authors： Jessani S,Gangopadhyay K,Patel JV,Lip GY,Millane T

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:The influence of cardiovascular risk factors/comorbidities on response to oral once-daily tadalafil 5 mg was explored in men with lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH). METHODS:This post hoc analysis pooled data from four double-blind studies in which 1498 men wit...

journal_title：International journal of clinical practice

authors： Vlachopoulos C,Oelke M,Maggi M,Mulhall JP,Rosenberg MT,Brock GB,Esler A,Büttner H

更新日期：2015-12-01 00:00:00

abstract：:Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells. It also exhibits antibacterial activity against Helicobacter pylori in vitro. During almost 10 years of clinical use, lansoprazole has prove...

journal_title：International journal of clinical practice

authors： Bown RL

更新日期：2002-03-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of adult blindness among individuals aged 50 and older in the Western world, with the neovascular form of AMD responsible for the most severe and rapid visual loss. Although monotherapy with currently available treatments can slow the rate of loss of vision i...

journal_title：International journal of clinical practice

authors： Kaiser PK,Do DV

更新日期：2007-03-01 00:00:00

abstract：:Patients with groin herniae do not always seek medical advice and, when listed for surgery, often wait many months for elective repair. We audited our emergency admissions for complicated groin herniae to establish whether a change in policy for elective surgery could lower their incidence. We performed a retrospectiv...

journal_title：International journal of clinical practice

authors： Malek S,Torella F,Edwards PR

更新日期：2004-02-01 00:00:00

abstract：:Both hepatitis B and hepatitis C are spread parenterally. Chronic hepatitis C is fast becoming the leading indication for liver transplantation. Most infected patients go on to develop chronic hepatitis, with approximately 20% developing liver cirrhosis or hepatocellular carcinoma after 20 years. Standard treatment no...

journal_title：International journal of clinical practice

authors： Alexander G,Walsh K

更新日期：2000-09-01 00:00:00

abstract：:Wiley has updated its publishing ethics guidelines, first published in 2006. The new guidelines provide guidance, resources and practical advice on ethical concerns that arise in academic publishing for editors, authors and researchers, among other audiences. New guidance is also included on whistle blowers, animal re...

journal_title：International journal of clinical practice

authors： Graf C,Deakin L,Docking M,Jones J,Joshua S,McKerahan T,Ottmar M,Stevens A,Wates E,Wyatt D

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Few published studies have examined survival rates for patients with metastatic colorectal cancer (mCRC) by number of lines of treatment received or stage at diagnosis. This study aims to evaluate survival and numbers of lines of treatment in USA mCRC managed care patients. METHODS:To evaluate the impact of ...

journal_title：International journal of clinical practice

authors： Seal B,Chastek B,Kulakodlu M,Valluri S

更新日期：2015-02-01 00:00:00

abstract：:Ezetimibe/simvastatin (INEGY), a dual inhibitor of both cholesterol production and absorption, is a new approach to the management of hyperlipidaemia. Recent studies have shown that it produces greater reductions in low-density lipoprotein (LDL) cholesterol than the single inhibition of statin therapy, enabling many m...

journal_title：International journal of clinical practice

authors： Kastelein JJ,Sankatsing RR

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The impact of robot-assisted techniques versus conventional freehand techniques in terms of the accuracy of pedicle screw placement remains conflicting. This meta-analysis was performed to evaluate this relationship. METHODS:A systematic literature search up to July 2020 was performed and 15 studies were de...

journal_title：International journal of clinical practice

authors： Fu W,Tong J,Liu G,Zheng Y,Wang S,Abdelrahim MEA,Gong S

更新日期：2020-12-28 00:00:00

abstract：INTRODUCTION:Peripartum cardiomyopathy (PPCM) is an uncommon form of congestive heart failure, afflicting obstetric patients around the time of delivery. The epidemiology of PPCM is infrequently reported. To the best of our knowledge, there has been no report from Asia. OBJECTIVE:To define the prevalence, presentation...

journal_title：International journal of clinical practice

authors： Chee KH,Azman W

更新日期：2009-05-01 00:00:00

abstract：:We reviewed the results of 22 operations performed on 21 patients for the relief of de Quervain's disease over the last six years. At a mean follow-up of 34 months (range 4-78 months), 18 of 22 wrists had complete relief of their original symptoms. One patient required reoperation because of inadequate decompression, ...

journal_title：International journal of clinical practice

authors： Mellor SJ,Ferris BD

更新日期：2000-03-01 00:00:00

abstract：:It is becoming increasingly common to offer primary percutaneous coronary intervention as first line treatment for ST elevation myocardial infarction (STEMI). In a subset of patients presenting with suspected STEMI, coronary arteries appear normal at coronary angiography. In this article, the current literature of thi...

journal_title：International journal of clinical practice

authors： Meryon I,Patel N,Millane T,Varma C

更新日期：2010-08-01 00:00:00

abstract：:Systolic heart failure (SHF) is associated with increased morbidity and mortality. Beta-blockers (BB) were shown to provide mortality benefit in patients with SHF, and currently indicated in all stages of patients with SHF. We evaluated the factors influencing the prescription of BBs at discharge in patients hospitali...

journal_title：International journal of clinical practice

authors： Yilmaz MB,Refiker M,Guray Y,Guray U,Altay H,Demirkan B,Caldir V,Korkmaz S

更新日期：2007-02-01 00:00:00