Abstract:
:Linear regression methods try to determine the best linear relationship between data points while correlation coefficients assess the association (as opposed to agreement) between the two methods. Linear regression and correlation play an important part in the interpretation of quantitative method comparison studies. Their major strength is that they are widely known and as a result both are employed in the vast majority of method comparison studies. While previously performed by hand, the availability of statistical packages means that regression analysis is usually performed by software packages including MS Excel, with or without the software programe Analyze-it as well as by other software packages. Such techniques need to be employed in a way that compares the agreement between the two methods examined and more importantly, because we are dealing with individual patients, whether the degree of agreement is clinically acceptable. Despite their use for many years, there is a lot of ignorance about the validity as well as the pros and cons of linear regression and correlation techniques. This review article describes the types of linear regression and regression (parametric and non-parametric methods) and the necessary general and specific requirements. The selection of the type of regression depends on where one has been trained, the tradition of the laboratory and the availability of adequate software.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Twomey PJ,Kroll MHdoi
10.1111/j.1742-1241.2008.01709.xsubject
Has Abstractpub_date
2008-04-01 00:00:00pages
529-38issue
4eissn
1368-5031issn
1742-1241pii
IJCP1709journal_volume
62pub_type
杂志文章,评审abstract::Hepatic endometriosis is extremely rare. The diagnosis is often missed and treatment is delayed. A 37-year-old woman was referred to the gynaecology department with vague abdominal pains. She had a past history of pelvic endometriosis and hysterectomy with bilateral salpingo-oophorectomy. Further investigations in due...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:AIM:To assess attitudes and beliefs towards benign prostatic hyperplasia (BPH)/ lower urinary tract symptoms (LUTS) and its treatment among patients and physicians in Latin America, Asia Pacific and the Commonwealth of Independent States (CIS). METHODS:Cross-sectional, quantitative study conducted between December 201...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/ijcp.12879
更新日期:2016-10-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) comprises a disease spectrum ranging from simple steatosis and steatohepatitis to cirrhosis. Based on its strongest risk factors namely visceral obesity and insulin resistance, NAFLD is thought to be the hepatic manifestation of the metabolic syndrome and is considered to be t...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02327.x
更新日期:2010-06-01 00:00:00
abstract::Monomeric prolactin (PRL) of molecular weight 23 kDa constitutes up to 95% of adult serum PRL. Macroprolactin is a large antigen-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating PRL. Thus, in most cases, hyperprolactinaemia is usually a result of high levels of mono...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1368-5031.2006.00732.x
更新日期:2006-04-01 00:00:00
abstract:AIM:The aim of this study was to compare ezetimibe/simvastatin combination therapy with intensified statin monotherapy as alternative treatment strategies to achieve the Joint British Societies (JBS)-2 and National Institute for Health and Clinical Excellence low-density-lipoprotein cholesterol (LDL-C) target of < 2 mm...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2010.02429.x
更新日期:2010-07-01 00:00:00
abstract::Overactive bladder (OAB) affects an estimated 49 million people in Europe, but only a minority receive appropriate treatment. Others are bothered by unacceptable levels of symptoms that severely impair their quality of life and represent a significant financial burden to themselves and to their healthcare providers. R...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2006.01127.x
更新日期:2006-10-01 00:00:00
abstract::TT virus (TTV) is a novel DNA virus that has been identified in patients with post-transfusional hepatitis of unknown aetiology. However, its pathogenic role in liver injury remains unclear. To determine its frequency and clinical impact in cryptogenic liver diseases, we investigated the TTV prevalence in patients wit...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Patients presenting to the emergency department with chest pain are evaluated by emergency physicians in hospitals without cardiology cover 24 h a day. The purpose of this study is to determine the consistency of electrocardiography (ECG) interpretation and chest pain likelihood classification between emergency physic...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-1241.2005.00788.x
更新日期:2006-10-01 00:00:00
abstract:AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijcp.12944
更新日期:2017-05-01 00:00:00
abstract:AIM:This study aimed to determine the impact of long-term treatment with continuous positive airway pressure (CPAP) and obstruction relieving surgical procedure on obstructive sleep apnoea syndrome (OSAS) patients on erectile function (EF). METHODS:Eighty male OSAS patients, suffering from erectile dysfunction (ED) we...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2012.02990.x
更新日期:2012-12-01 00:00:00
abstract::Men with cardiovascular disease (CVD) are more likely to have erectile dysfunction (ED) than the general population, as both conditions share risk factors and some drugs used to treat CVD may induce ED as a side-effect. This study was undertaken to assess the efficacy and safety of sildenafil citrate for the treatment...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2001-04-01 00:00:00
abstract::To investigate ethnic differences and the effect of age and education on awareness and attitudes of women towards hormone replacement therapy (HRT), we conducted a questionnaire survey of 180 women attending a gynaecology clinic, of whom 152 (84.4%) responded. Seventy-one of the women had heard of HRT. Awareness of HR...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The impact of robot-assisted techniques versus conventional freehand techniques in terms of the accuracy of pedicle screw placement remains conflicting. This meta-analysis was performed to evaluate this relationship. METHODS:A systematic literature search up to July 2020 was performed and 15 studies were de...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13964
更新日期:2020-12-28 00:00:00
abstract:OBJECTIVE:To assess secondary prevention of fragility fractures by orthopaedic surgeons in the UK and study the effect of multidisciplinary approach in providing secondary prevention. METHODS:A survey was conducted consisting of a postal questionnaire sent to 1000 UK orthopaedic surgeons. 750 valid responses were rece...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01662.x
更新日期:2008-03-01 00:00:00
abstract::The use of hormone replacement therapy (HRT) for cardiovascular risk reduction remains uncertain. Although previous epidemiological surveys have suggested a clear benefit and nearly 50% mortality risk reduction with HRT in postmenopausal women, recent randomised trials have largely failed to support this. The epidemio...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract::This trial assessed whether a simple clinical tool can be used to stratify patients with diabetes, according to risk of developing foot ulceration. This was a prospective, observational follow-up study of 3526 patients with diabetes (91% type 2 diabetes) attending for routine diabetes care. Mean age was 64.7 (range 15...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1368-5031.2006.00899.x
更新日期:2006-05-01 00:00:00
abstract::Summary The objective of this study was to determine whether Ramadan is changing frequencies and demographics of visits due to certain diseases. Data obtained from the charts of the adult patients admitted into the emergency department (ED) due to 10 predetermined entities between 2000 and 2004 were analysed. Demograp...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2005.00460.x
更新日期:2005-08-01 00:00:00
abstract:AIMS:Many tachy-brady syndrome (TBS) patients, are implanted a permanent pacemaker (PPM) to allow continuation of anti-arrhythmic drug (AAD) therapy to maintain sinus rhythm. Many of these PPM's are implanted as a preventive measure, in absence of symptomatic bradycardia. Our primary aim was to evaluate pacing use amon...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13583
更新日期:2020-10-01 00:00:00
abstract::Lithium salts have been used in medicine for over a century and are a widely accepted treatment. Clinical practice in the London borough of Barnet led us to suspect that agreed guidelines were not being followed. We checked them against published guidelines and followed up their implementation. A list of patients on l...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::The potential effect of orlistat on cardiovascular co-morbidities may have been previously underestimated. This study assesses the efficacy of orlistat therapy for weight loss and cardiovascular risk factor reduction in obese patients with cardiovascular risk. This was a 54-week, double-blind, randomised, placebo-cont...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Studies in the primary care setting are of high interest for assessing the management situation of patients with manifestations of atherothrombosis. AIMS:Therefore, we documented diagnostic procedures, characteristics, and management of patients with symptomatic and asymptomatic peripheral arterial disease ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2010.02337.x
更新日期:2010-06-01 00:00:00
abstract::Amyloidosis commonly involves the liver but clinical features of liver disease are rare. We report a case of cholestasis and hepatic failure in an 85-year-old man due to primary amyloidosis. This has not been reported previously in anyone of this advanced age. We discuss the clinical features of hepatic amyloidosis an...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract::Sarcoidosis is a chronic disease with an unknown aetiology. Our aim was to evaluate the pattern of seasonality of stage 1 sarcoidosis subjects who had symptoms by all cases, by age and by both genders. In this study, we used Roger's test for cyclic variation to prove that this seasonal variation was more than chance. ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2005.00773.x
更新日期:2006-11-01 00:00:00
abstract:AIMS:We aimed to compare the effect of risedronate (RIS) and teriparatide (TPTD) (recombinant human parathyroid hormone 1-34) on bone turnover markers in women with postmenopausal osteoporosis. METHODS:Forty-four Caucasian women (age 65.1 +/- 1.6 years) with postmenopausal osteoporosis were randomly assigned to receiv...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-1241.2008.01768.x
更新日期:2008-06-01 00:00:00
abstract::We report a case of Pott's puffy tumour in a 12-year-old. Owing to the late development of the frontal sinuses, frontal sinus infection in children is rare. When present it can lead to osteomyelitis associated with forehead swelling. Early diagnosis and active treatment prevent progression to life-threatening intracra...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::The effects of diltiazem treatment on symptoms of chronic anal fissures and their long-term outcome were investigated. One hundred and twelve patients were supplied with 6-week course of 2% diltiazem cream for twice-daily topical application. The medical notes and extended follow-up by telephone for 112 patients were ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.00895.x
更新日期:2006-11-01 00:00:00
abstract::After more than 20 years, the conflict of interest (COI) movement has failed to substantiate its central claim that interactions between physicians, researchers and the medical products industry cause physicians to make clinical decisions that are adverse to the best interests of their patients. The COI movement's ins...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12366
更新日期:2014-06-01 00:00:00
abstract::It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) and if the impact of inflammatory response can be diminished by eradication of the infection. To evaluate if ther...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01098.x
更新日期:2008-05-01 00:00:00
abstract::The aim was to evaluate 24 hr urine catecholamine, HMMA and HVA excretion in relation to ploidy in phaeochromocytoma. Data from five diploid and nine tetraploid tumours showed a significant reduction in urine noradrenaline (p = 0.02) and HMMA (p = 0.03) in diploid tumours but no difference in adrenaline, dopamine and ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to investigate the relationship between the use of medicinal plants and medication adherence in elderly people. METHODS:Observational, cross-sectional study of elderly residents in Cuité-PB, Northeastern Brazil, through a household survey. A stratified proportional and systema...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12773
更新日期:2016-03-01 00:00:00