Cost-effectiveness of acarbose for the management of impaired glucose tolerance in Sweden.

Abstract:

:We assessed the cost-effectiveness of acarbose in the management of patients with impaired glucose tolerance (IGT) in Sweden, based on progression to type 2 diabetes (T2D) and cardiovascular (CV) events reported in the STOP-NIDDM trial population, including high-risk subgroups. The cost per patient free from T2D was SEK28,000 or SEK1260 per diabetes free month prior to progression to T2D. The cost per patient free from CV events was SEK101,000 or SEK5000 per CV event free month. For the high CV risk subgroups, acarbose treatment dominated placebo (i.e. acarbose was more effective, less costly). Acarbose significantly reduces the incidence of diabetes and CV events in IGT patients. We predict this may translate into healthcare cost savings that partially or, in patients at high CV risk, fully offset the cost of acarbose. We conclude that acarbose is likely to be cost-effective in the management of impaired glucose tolerance.

journal_name

Int J Clin Pract

authors

Quilici S,Chancellor J,Maclaine G,McGuire A,Andersson D,Chiasson JL

doi

10.1111/j.1368-5031.2005.00629.x

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

1143-52

issue

10

eissn

1368-5031

issn

1742-1241

pii

IJCP629

journal_volume

59

pub_type

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