Cola-induced hypokalaemia: pathophysiological mechanisms and clinical implications.

Abstract:

BACKGROUND/AIMS:The consumption of soft drinks has increased considerably during the last decades. Among them, the cola-based preparations are possibly the refreshments with the largest sales worldwide. In addition to the possible detrimental effects of moderate, chronic cola consumption, it has been proposed that the consumption of large amounts of cola-based soft drinks may result in severe hypokalaemia. METHODS:In this review, we discuss the clinical significance of these disturbances and summarise the pathophysiological mechanism that may underlie the development of this rare, but potentially severe, side effect. RESULTS/CONCLUSION:Several lines of evidence suggest that the chronic consumption of large amounts of cola soft drinks may adversely affect potassium homeostasis and result in potentially severe conditions such as hypokalaemic myopathy.

journal_name

Int J Clin Pract

authors

Tsimihodimos V,Kakaidi V,Elisaf M

doi

10.1111/j.1742-1241.2009.02051.x

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

900-2

issue

6

eissn

1368-5031

issn

1742-1241

pii

IJCP2051

journal_volume

63

pub_type

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