Abstract:
AIMS:To establish the value of the first 3 years of a cardiovascular risk factor clinic in tackling the major risk factors for cardiovascular disease (CVD). METHODS:A database review of all 339 patients referred to the clinic. RESULTS:Blood pressure levels in the hypertensive patients were significantly reduced and 9% of the smokers managed to quit for 12 months, half of them subsequently relapsing. Ninety-eight oral glucose tolerance tests were performed and 40% were abnormal yielding 10 patients with hitherto unsuspected diabetes and 29 with impaired glucose tolerance. Sixty-four of the 97 referrals of patients in the primary prevention group (no evidence of CVD) were found to have calculated Framingham coronary heart disease risk estimates of < 15% per decade, the lowest being 0.3%. Lipid levels were significantly reduced in both the hypercholesterolaemic (n = 290) and hypertriglyceridaemic (n = 49) patient groups through the use of more potent statins, extensive use of combination therapy and appropriate use of fibrates and omega-3 fish oil supplements. The annual drug cost per patient treated only increased from 310.72 pounds sterling to 398.08 pounds sterling, yet there was a 3.5-fold increase in the number of patients achieving the General Medical Services 2 target of a total cholesterol < 5 mmol/l and a 4.5-fold increase in patients achieving the Joint British Societies 2 target of a low-density lipoprotein (LDL) cholesterol < 2 mmol/l. CONCLUSION:The need for a specialist clinic was demonstrated by the 66% of primary prevention referrals who did not meet the current NICE treatment threshold. Additionally, the clinic was able to diagnose and treat 39 patients with undiagnosed diabetes mellitus/impaired glucose tolerance and 12 with hypothyroidism. LDL cholesterol was reduced overall by 36% implying a greater than one-third reduction in future cardiovascular events before the improvements in blood pressure control and smoking cessation are included and this was achieved at marginal extra cost to the mean drug bill at referral.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Martin SC,Viljoen Adoi
10.1111/j.1742-1241.2007.01667.xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
961-6issue
6eissn
1368-5031issn
1742-1241pii
IJCP1667journal_volume
62pub_type
杂志文章abstract::'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2011.02825.x
更新日期:2012-01-01 00:00:00
abstract:AIMS:To investigate the association between the self-perception period of OAB symptoms (SP-OAB) and the overactive bladder symptom score (OABSS), along with related sociodemographic and lifestyle factors. METHODS:This was a cross-sectional study comprised of 192 men aged 40 years and older who participated in a prosta...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12080
更新日期:2013-08-01 00:00:00
abstract::There has been much debate over the past 50 years concerning the association between colorectal carcinoma and inflammatory bowel disease. Until recently, it was widely accepted there was a higher risk in those with widespread ulcerative colitis. However, evidence now suggests an almost equal incidence in those with Cr...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:The coronavirus disease 2019 (COVID-19) has had a rapid global spread. All individuals of all age groups are at risk of COVID-19. This study aims to describe the knowledge and attitude of Jordanian parents regarding COVID-19 in children, including clinical signs of the disease, modes of transmission and prot...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13671
更新日期:2021-02-01 00:00:00
abstract:INTRODUCTION:Niacin is underutilised because of flushing. Lack of a quantitative tool to assess niacin-induced flushing has precluded the objective evaluation of flushing associated with extended-release (ER) niacin formulations. We developed the Flushing Symptom Questionnaire((c)) (FSQ), a quantitative tool to assess ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Mobile smart phones have become increasingly integrated into the practice of doctors and allied medical professionals. Recent studies suggest them to represent reservoirs for pathogens with potential to cause nosocomial infections. This study aimed to investigate the level of contamination on phones used on ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12448
更新日期:2014-09-01 00:00:00
abstract::The phenomenon of spontaneous remission is one of the less well known aspects of the leukaemias. Spontaneous remission has been reported in both acute and chronic leukaemia. The mechanism is unclear but may involve immune modulation related to an intercurrent infection or transfusion of blood products. We present a ra...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1742-1241.2011.02633.x
更新日期:2011-03-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02183.x
更新日期:2009-10-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01136.x
更新日期:2007-01-01 00:00:00
abstract::Twenty cases of tuberculous meningitis were diagnosed at the Hamad Medical Corporation between 1990 and 1995. Most of the patients (90%) were expatriates. The most common presenting features were fever, headache, neck stiffness and altered mental status. Five patients were in stage 1 disease at the time of presentatio...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract:AIMS:This study examines women's experience of healthcare following the referral for hysterosalpingography (HSG) after a period of subfertility. These otherwise fit and healthy women enter the healthcare system and their only problem is a failure to become pregnant. They find themselves trying to negotiate a system des...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2010.02431.x
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:Cutaneous leishmaniasis (CL) is a skin disease characterised by prolonged nodulo-ulcerative lesions of the skin that heals with atrophic scar. Clinical features of CL vary depending on the type of parasite and host immune resistance. The aim of this study was to investigate the clinical features of atypical a...
journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2020-10-26 00:00:00
abstract::Major concerns remain about the reliability of tympanic thermometers. The aim of this study was to investigate the agreement between rectal and tympanic thermometry and compare this with the repeatability of each method in patients with acute stroke. Tympanic temperature readings were from 0.7 degrees C below to 0.8 d...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:AIMS:To evaluate the efficacy of switching from a previous statin monotherapy to ezetimibe/simvastatin (EZE/SIMVA) 10/20 mg vs. rosuvastatin (ROSUVA) 10 mg. METHODS:In this randomised, double-blind study, 618 patients with documented hypercholesterolaemia [low-density lipoprotein cholesterol (LDL-C) > or = 2.59 and < ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2009.02022.x
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Incretin-based therapies offer another treatment option for patients with type 2 diabetes. Agents that provide glycaemic control in addition to attenuating cardiovascular disease (CVD) risk factors are important for diabetes management. This review will focus on the off-target effects of incretin-based thera...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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更新日期:2015-05-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析
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更新日期:2016-07-01 00:00:00
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::This study explored the characteristics associated with the use of self-care products and practices by people rehabilitating from stroke. A cross-sectional sub-study of the Sax Institute's 45 and Up Study in which 1300 participants who had indicated a doctor had diagnosed them as having had a stroke were mailed a sub-...
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更新日期:2020-11-07 00:00:00
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journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2002-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
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更新日期:2010-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:1997-06-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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更新日期:2018-01-01 00:00:00