Abstract：
:Splenic tumours are occasionally found during routine physical check-ups or elective abdominal image studies. Histologically, most splenic tumours are of benign vascular origin. To avoid unnecessary surgery for asymptomatic patients with benign splenic tumours and clarify the clinicopathological features of spleen tumours, this study gathered 44 cases of primary or isolated metastatic spleen tumours confirmed by pathology from surgery specimens or biopsies. The differences in clinicopathological features and image presentations between benign and malignant spleen tumour were investigated. Thirty-two cases involved benign tumours while 12 cases were malignant. Among the benign tumours, vascular originating tumours were most common (with 14 cases of cavernous haemangiomas, 13 cases of lymphangioma, three cases of lymphangiohaemangioma and one case of Littoral cell angioma). Notably, one, case of inflammatory pseudotumour because of Schistosoma parasite infection was also noted. Among the malignant tumours, there were four cases of angiosarcomas with vascular endothelium origins, as well as lymphomas and six metastatic tumours. Image studies were non-specific. Image study alone is an inadequate basis for making differential diagnoses between benign and malignant tumours. Instead, pathological studies are required for a final diagnosis. Using previous studies and this investigation, fine needle aspiration biopsy of spleen tumours with the help of ultrasonic or computed tomography appears a safe and effective method for obtaining biopsy specimens. Splenectomy is recommended only for patients with malignancies or complications such as intractable abdominal pain, coagulopathy or tumour rupture with an unstable haemodynamic state.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Chen LW,Chien RN,Yen CL,Chang LCdoi
10.1111/j.1742-1241.2004.00009.xsubject
Has Abstractpub_date
2004-10-01 00:00:00pages
924-7issue
10eissn
1368-5031issn
1742-1241journal_volume
58pub_type
杂志文章abstract：AIMS:To examine the relationship between costs of hyperglycaemia drug treatment and glycemic control amongst people with type 2 diabetes (T2D). METHODS:This observational study utilised data from the QUALIDIAB database on 3,452 T2D patients seen in Diabetes Centers in Argentina. Patients were classified according to t...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13336
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this study is to compare the thyroid hormone (TH) profile in male infertile subjects with normal and altered sperm parameters and assess its relationship with spermogram and reproductive hormones. DESIGN:This cross-sectional study was conducted in Karachi from August 2017 till September 2018 o...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13555
更新日期：2020-09-01 00:00:00
abstract：:In the vast majority of cases, Clostridium difficile-associated diarrhoea and pseudomembranous colitis develop following the use of antibiotics. We report a case in which C. difficile-associated diarrhoea was diagnosed in the absence of previously reported predisposing factors. It transpired that the patient had a col...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Ezetimibe/simvastatin (INEGY), a dual inhibitor of both cholesterol production and absorption, is a new approach to the management of hyperlipidaemia. Recent studies have shown that it produces greater reductions in low-density lipoprotein (LDL) cholesterol than the single inhibition of statin therapy, enabling many m...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2005.00737.x
更新日期：2005-12-01 00:00:00
abstract：:Tumours of the perianal region and anal canal are uncommon and can present in a variety of ways. Acute anorectal sepsis is a common condition that usually presents as a painful lump close to the anal margin. Tumours in the perianal region may mimic the symptoms and signs of anorectal sepsis, thereby leading to a delay...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：INTRODUCTION:Patients with atrial fibrillation (AF) are more symptomatic than patients with sinus rhythm. However, it is unknown what per cent of time spent in AF is associated with symptoms. METHODS:We used a limited access dataset from the Atrial Fibrillation Follow-up Investigation of Rhythm Management trial. Patie...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12262
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Antibiotics are widely used and inaccurate or inappropriate prescription of antibiotics causes a significant increase in the prevalence of multidrug-resistant bacterial infections among children. This research aimed to study antibiotic prescriptions in hospitalised paediatric patients and to determine the pr...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13782
更新日期：2020-10-24 00:00:00
abstract：BACKGROUND:Overactive bladder (OAB) syndrome has a diverse etiology that disrupts quality of life domains in affected patients. OAB is significantly under-recognised and undertreated, especially in the primary care setting. In order to educate primary care providers about OAB recognition, evaluation and management, we ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13604
更新日期：2020-11-01 00:00:00
abstract：:Snoring is a very common source of complaints from partners and neighbours. Snorers themselves are less likely to be affected, unless they have associated daytime sleepiness caused by the sleep disruption from obstructive sleep apnoea. There is increasingly firm evidence that obstructive sleep apnoea is associated wit...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-01 00:00:00
abstract：:Summary The objective of this study was to determine whether Ramadan is changing frequencies and demographics of visits due to certain diseases. Data obtained from the charts of the adult patients admitted into the emergency department (ED) due to 10 predetermined entities between 2000 and 2004 were analysed. Demograp...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2005.00460.x
更新日期：2005-08-01 00:00:00
abstract：:The objective of this study was to investigate the impact of rivastigmine therapy on attention, apathy, anxiety and agitation in patients with mild-to-moderate Alzheimer's disease (AD) in a real-world clinical setting. Patients with mild-to-moderate AD were enrolled in the study by physicians across Canada. They were ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1742-1241.2007.01387.x
更新日期：2007-06-01 00:00:00
abstract：:Non-small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It is predominantly a disease of the elderly with the median age at diagnosis 68 years. Unfortunately, the majority of patients present with advanced disease whereby palliation is the primary aim of treatment. The elderly have a lo...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2005.00795.x
更新日期：2006-03-01 00:00:00
abstract：AIMS:To investigate the evolution of the quality of life of patients with chronic obstructive pulmonary disease (COPD) and quantify the impact of exacerbations on the deterioration of quality of life over 2 years. METHODS:Multicentre, observational, prospective 2-year study carried out in primary care. Patients with C...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1742-1241.2008.01707.x
更新日期：2008-04-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) comprises a disease spectrum ranging from simple steatosis and steatohepatitis to cirrhosis. Based on its strongest risk factors namely visceral obesity and insulin resistance, NAFLD is thought to be the hepatic manifestation of the metabolic syndrome and is considered to be t...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2009.02327.x
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:To evaluate the efficacy of Daptomycin (DPT) lock therapy in the treatment of Grampositive long-term catheter-related bloodstream infections (LT-CRBI). PATIENTS AND METHODS:A retrospective review of all patients receiving DPT lock therapy for the treatment of LT-CRBI from December 2009 to May 2010 was con...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2011.02830.x
更新日期：2012-03-01 00:00:00
abstract：AIMS:Strong evidence indicates that drugs reduce blood lipids and improve cardiovascular end-points, leading to their wide usage. However, the success of these drugs can be affected by poor patient's adherence to prescribed medication. This study aimed to evaluate medication adherence in patients with dyslipidaemia in ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13511
更新日期：2020-07-01 00:00:00
abstract：AIMS:Little is known on factors associated with switching and combination use of antidepressants. Our aim was to describe such use and to analyse the association with socioeconomic factors and level of care in Swedish adults aged 20-34 years. METHODS:Individuals, aged 20-34 years, who purchased an antidepressant in Ja...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12263
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to explore the feasibility of using low dose radiation and low concentration contrast media in enhanced CT examinations in children with congenital heart disease. MATERIALS AND METHODS:Ninety patients with congenital heart disease were randomly divided into three groups of 30 patien...
journal_title：International journal of clinical practice
pub_type： 杂志文章,随机对照试验
doi：10.1111/ijcp.12857
更新日期：2016-09-01 00:00:00
abstract：:Amyloidosis commonly involves the liver but clinical features of liver disease are rare. We report a case of cholestasis and hepatic failure in an 85-year-old man due to primary amyloidosis. This has not been reported previously in anyone of this advanced age. We discuss the clinical features of hepatic amyloidosis an...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:People with genuine anxiety disorders can be misdiagnosed and mismanaged, because of negative public and professional attitudes to anxiety and the 'worried well'. Misdiagnosis includes not taking symptoms seriously and giving patients pejorative labels such as 'personality disorder' or 'inadequate'. This can lead to m...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:In late July, Cyprus experienced the second epidemic wave of COVID-19. We present the steps taken by the government and evaluate their effect on epidemic trends. MATERIALS:Cyprus Press and Information Office data were analysed. Using an R-based forecasting program, two models were created to predict cases u...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13944
更新日期：2020-12-18 00:00:00
abstract：:In this journal, Cummins et al reported an experiment that examined clinicians' predictions of causes of death from subjects' pre-morbid photographs. They found that clinicians performed at chance. The validity of two of their other conclusions are challenged. First, that clinicians routinely form impressions of how a...
journal_title：International journal of clinical practice
pub_type： 评论,杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.00998.x
更新日期：2007-08-01 00:00:00
abstract：:Men with cardiovascular disease (CVD) are more likely to have erectile dysfunction (ED) than the general population, as both conditions share risk factors and some drugs used to treat CVD may induce ED as a side-effect. This study was undertaken to assess the efficacy and safety of sildenafil citrate for the treatment...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2001-04-01 00:00:00
abstract：:Efficacy and tolerability of diclofenac sustained-released (SR) 75 mg tablets taken b.i.d. were compared with that of enteric-coated diclofenac sodium 50 mg tablets given t.i.d. in a seven-day, randomised, double-blind, double-dummy, parallel groups study in 294 outpatients suffering from painful femorotibial or hip o...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1997-09-01 00:00:00
abstract：:Proton pump inhibitors are highly effective acid suppressants with decades of use highlighting positive outcomes in millions of patients worldwide, and they offer minimal risk of adverse events. PPIs are considered overutilised when prescribed without an appropriate indication, when patients are left on them 'indefini...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2012.02921.x
更新日期：2012-06-01 00:00:00
abstract：:Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells. It also exhibits antibacterial activity against Helicobacter pylori in vitro. During almost 10 years of clinical use, lansoprazole has prove...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：AIMS:The impact of ongoing PCR positivity on COVID-19 patients and the strategy and period of isolation were not fully understood. We aimed to investigate the factors that cause prolonged PCR positivity and its clinical impact on COVID-19 infection. In addition, we searched for an answer on what length of time would be...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.14025
更新日期：2021-01-15 00:00:00
abstract：AIMS:Patients with advanced type 2 diabetes (T2D) and high glycated haemoglobin (HbA1c) values can be difficult to treat because of their severe metabolic disease. This pooled analysis examined the treatment effects of exenatide twice daily (BID), exenatide once weekly (QW) and insulin in patients with high baseline Hb...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/ijcp.13029
更新日期：2017-12-01 00:00:00
abstract：:In this review, we discuss right-sided heart valve disease, namely tricuspid regurgitation (TR), tricuspid stenosis, pulmonary regurgitation, pulmonary stenosis and right-sided endocarditis. These are frequently seen in conjunction with other diseases, making assessment of their significance more difficult, but it has...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12485
更新日期：2014-10-01 00:00:00
