Abstract:
:The aim of this study was to review the application of antimicrobial stewardship principles to the management of community-acquired pneumonia (CAP). Data from 14 published clinical studies, meta-analyses and practice guidelines regarding the application of antimicrobial stewardship strategies to the management of CAP were identified and analysed. In the context of CAP, application of stewardship strategies (alone or in combination) has been shown to increase physician awareness of guidelines, improve appropriate antimicrobial use and reduce unnecessary antimicrobial prescribing. In addition, application has had a profound favourable impact on patient outcomes, including decreased 30-day mortality and in-hospital mortality rates, reduced length of hospital stay, reduced treatment failure rates and reduced healthcare costs. Antimicrobial stewardship programmes have been demonstrated to successfully increase the level of appropriate antibiotic prescribing, reduce pathogen resistance and improve clinical outcomes in the management of CAP within hospitals. Studies have also shown that adherence to evidence-based guidelines, even at the level of the individual clinician, can have a profound and positive impact on patient outcomes and healthcare costs. Adherence to evidence-based guidelines can have a profound and positive impact on patient outcomes and healthcare costs.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Bosso JA,Drew RHdoi
10.1111/j.1742-1241.2011.02704.xsubject
Has Abstractpub_date
2011-07-01 00:00:00pages
775-83issue
7eissn
1368-5031issn
1742-1241journal_volume
65pub_type
杂志文章,评审abstract:AIM:This study aimed to determine the impact of long-term treatment with continuous positive airway pressure (CPAP) and obstruction relieving surgical procedure on obstructive sleep apnoea syndrome (OSAS) patients on erectile function (EF). METHODS:Eighty male OSAS patients, suffering from erectile dysfunction (ED) we...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2012.02990.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:In clinical practice, hyponatraemia was frequently found in patients with hydrocephalus. We conducted this study to determine the prevalence and risk factors for hyponatraemia in patients with normal pressure hydrocephalus (NPH). METHODS:We retrospectively reviewed all patients with NPH who were admitted to...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2008.01925.x
更新日期:2009-03-01 00:00:00
abstract::The aim of thromboprophylaxis is to minimise the incidence of clinically relevant venous thromboembolism (VTE) but in many trials designed to determine the efficacy of thromboprophylactic agents, asymptomatic VTE is included in the primary endpoint. Since asymptomatic events occur much more frequently than symptomatic...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Smoking has important health and economic consequences for individuals and society. This study expands the understanding of work-related burden associated with smoking and benefit of smoking cessation across the US, European Union (EU) and China using large-scale, representative survey methodology. METHODS:...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12900
更新日期:2017-01-01 00:00:00
abstract::This randomised, double-blind, placebo-controlled, parallel-group study compared the efficacy and tolerability of lumiracoxib (a novel COX-2 selective inhibitor) with rofecoxib, celecoxib and placebo in patients with moderate-to-severe post-operative dental pain. Following third molar extraction, patients received sin...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1368-5031.2004.00155.x
更新日期:2004-03-01 00:00:00
abstract:INTRODUCTION:Niacin is underutilised because of flushing. Lack of a quantitative tool to assess niacin-induced flushing has precluded the objective evaluation of flushing associated with extended-release (ER) niacin formulations. We developed the Flushing Symptom Questionnaire((c)) (FSQ), a quantitative tool to assess ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2008.01739.x
更新日期:2008-06-01 00:00:00
abstract::It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) and if the impact of inflammatory response can be diminished by eradication of the infection. To evaluate if ther...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01098.x
更新日期:2008-05-01 00:00:00
abstract::The aim of this study was to compare the safety and efficacy of budesonide/formoterol 160/4.5 microg, two inhalations twice daily, with that of the mono-products administered at the same daily doses via separate inhalers. A total of 586 patients (mean age 45 years) was included in this six-month, open, randomised, mul...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2002-07-01 00:00:00
abstract::In this review, we discuss right-sided heart valve disease, namely tricuspid regurgitation (TR), tricuspid stenosis, pulmonary regurgitation, pulmonary stenosis and right-sided endocarditis. These are frequently seen in conjunction with other diseases, making assessment of their significance more difficult, but it has...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12485
更新日期:2014-10-01 00:00:00
abstract::Tonsillectomy is the most commonly performed otolaryngological procedure in most units. There is considerable financial pressure to perform paediatric tonsillectomy as a day case. Responding to concern that day case tonsillectomy might not be welcomed by parents or felt to be in the best interests of the patients, we ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::Kaposi's sarcoma (KS) is a recognised complication following kidney transplantation, but the incidence varies according to the geographical area. Although it is a rare tumour, its incidence increases dramatically after solid-organ transplantation. The immunosuppressive medications reactivate human herpes virus 8, whic...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.00815.x
更新日期:2006-11-01 00:00:00
abstract::A patent foramen ovale (PFO) has long been implicated as a potential mechanism for cryptogenic stroke (CS), which accounts for up to 40% of all cases of ischaemic stroke. Although there is a strong association between a PFO and CS, there is less evidence that percutaneous closure of the defect, as opposed to medical t...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/ijcp.12312
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Incretin-based therapies offer another treatment option for patients with type 2 diabetes. Agents that provide glycaemic control in addition to attenuating cardiovascular disease (CVD) risk factors are important for diabetes management. This review will focus on the off-target effects of incretin-based thera...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/ijcp.12572
更新日期:2015-05-01 00:00:00
abstract:AIM:To evaluate whether administration of long-acting basal insulin analogue plus oral antidiabetic drugs (OADs) improves glycaemic control in type 2 diabetic patients with glycosylated haemoglobin (HbA1c) > 7% (53 mmol/mol) under premixed insulin therapy. METHODS:This is a multicentre, observational, retrospective st...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-1241.2012.03000.x
更新日期:2012-10-01 00:00:00
abstract::Exaggerated reactions to insect bites are characteristic of patients with haemoproliferative disorders, particularly chronic lymphocytic leukaemia (CLL). Skin lesions usually appear after the diagnosis of leukaemia and seem unrelated to laboratory findings, disease course or therapy. Rarely, the eruption may precede t...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2004.00116.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Complementary medicine and alternative approaches to chronic and intractable health conditions are increasingly being used, and require critical evaluation. OBJECTIVE:The aim of this review was to systematically evaluate available evidence for the effectiveness and safety of instruction in the Alexander Tec...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2011.02817.x
更新日期:2012-01-01 00:00:00
abstract:AIMS:We prospectively enrolled 207 patients (121 were 75 or older and 86 younger than 75) who were admitted to three Respiratory Monitoring Units. The primary outcomes were intubation and mortality rates; the secondary outcomes were changes in arterial blood gases analysis, non-invasive ventilation (NIV) duration and l...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12484
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:We recently described early rigid retrograde endoscopic realignment of the disrupted urethra under caudal anaesthesia in the outpatient setting. This retrospective study was performed to evaluate our medium-term results. PATIENTS AND METHODS:A retrospective review of patients who had early rigid retrograde e...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01481.x
更新日期:2010-01-01 00:00:00
abstract::Headache is frequently reported as one of the neurological manifestations of essential thrombocythaemia (ET) and other myeloproliferative neoplasms. It is associated with considerable morbidity; yet, it is a frequently under-recognised symptom. In patients with ET, headaches may be attributable to the disease, to the ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2012.02986.x
更新日期:2012-10-01 00:00:00
abstract::The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1742-1241.2011.02633.x
更新日期:2011-03-01 00:00:00
abstract::The rationale for medical therapy for otospongiosis is to slow down and eventually stop the phase of bone resorption. There is some increase in the incidence of stapedial otospongiosis in a low-fluoride area compared with a high-fluoride area. Sodium fluoride treatment has a role to play in preventing the onset and pr...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02046.x
更新日期:2010-01-01 00:00:00
abstract::We reviewed the results of 22 operations performed on 21 patients for the relief of de Quervain's disease over the last six years. At a mean follow-up of 34 months (range 4-78 months), 18 of 22 wrists had complete relief of their original symptoms. One patient required reoperation because of inadequate decompression, ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::In recent years the complexities and heterogeneity of polycystic ovarian syndrome (PCOS) have been recognised. Most PCOS sufferers with amenorrhoea, menstrual dysfunction, hirsutism, acne and infertility can be evaluated and safely managed in primary care. It is prudent to remember that all women with PCOS are at risk...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:In 2006, the American Diabetes Association and the European Association for the Study of Diabetes established a consensus algorithm (ADA/EASD-2006) for the adjustment of drug therapy for type 2 diabetes mellitus (T2DM). AIMS:To study glycaemic control in T2DM patients and the implementation of the ADA/EASD-...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/ijcp.12251
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To evaluate state and trait form of anxiety and current depression in patients affected by gastrointestinal diseases. METHODS:We studied 1641 outpatients with gastrointestinal disorders, consecutively referred to our Internal Medicine outpatients from 1997 to 2005. State and trait anxiety were assessed by t...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2008.01763.x
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:The relationship between psoriasis and cardiomyopathy is understudied in Indian patients. OBJECTIVE:We evaluated psoriasis patients for cardiomyopathy and other echocardiographic abnormalities. METHODS:About 98 (M:F = 67:31) patients with mild to moderate psoriasis aged 18-75 years (mean ± SD = 42.12 ± 12....
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13756
更新日期:2020-10-16 00:00:00
abstract::Obesity is the major risk factor for the development of hypertension. This association accentuates the risk of cardiovascular disease, as it is frequently accompanied by the components of the metabolic syndrome. This randomised open parallel study evaluated the chronic effects of moxonidine--a selective imidazoline re...
journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1368-5031.2006.00951.x
更新日期:2006-05-01 00:00:00
abstract::Riedel's thyroiditis (RT) is an extremely rare form of chronic thyroiditis, characterised by a fibroinflammatory process which partially destroys the thyroid, often involving surrounding tissues. We describe an unusual case of RT in a 38-year-old woman, and discuss its typical clinical, pathological, ultrasound, radio...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Zoledronic acid inhibits bone resorption for up to 12 months. It is not known whether the duration of this antiresorptive effect extends beyond this period of time. The aim of this study was to evaluate the changes in bone turnover at 12 months (T12) and 18 months (T18) after a single injection of 4 mg of zoledronic a...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01392.x
更新日期:2007-06-01 00:00:00
abstract::Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells. It also exhibits antibacterial activity against Helicobacter pylori in vitro. During almost 10 years of clinical use, lansoprazole has prove...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2002-03-01 00:00:00