Failure to detect HLA-A*6802-restricted CD8+ T cells specific for Chlamydia trachomatis antigens in subjects from trachoma-endemic communities.

abstract：:Skin nuclear speckled IgG deposition was noted in seven patients. The patients' clinical courses satisfied at least four of the preliminary criteria of the American Rheumatism Association for the diagnosis of systemic lupus erthematosus (SLE). Examination of approximately 700 additional biopsies from patiets with SLE,...

journal_title：Clinical and experimental immunology

authors： Shu S,Provost T,Croxdale MB,Reichlin M,Beutner EH

更新日期：1977-02-01 00:00:00

abstract：:Dendritic cells were enriched from adenoids of children with otitis media with effusion (OME) by density gradient centrifugation and culture techniques. An enrichment of 40-140-fold was obtained for dendritic cells. These cells were identified using morphology, enzyme cytochemistry, immunocytochemistry and functional ...

journal_title：Clinical and experimental immunology

authors： van Nieuwkerk EB,van der Baan S,Richters CD,Kamperdijk EW

更新日期：1992-05-01 00:00:00

abstract：:Secretory IgA antibody responses such as those directed against respiratory and enteric pathogens, may be impaired in protein-calorie malnutrition. In previous studies using a rat model of the mucosal immune response to cholera toxin, as little as 2 weeks of severe protein deprivation markedly impaired mucosal anti-to...

journal_title：Clinical and experimental immunology

authors： Koster F,Pierce NF

更新日期：1985-04-01 00:00:00

abstract：:Vacuum-assisted closure involving the implantation of polyvinyl alcohol foam is a technique recently developed for the treatment of patients suffering from either wound infection or chronic wounds. This method has been shown to improve and accelerate wound healing. However, little is known about the cell populations t...

journal_title：Clinical and experimental immunology

authors： Gouttefangeas C,Eberle M,Ruck P,Stark M,Müller JE,Becker HD,Rammensee HG,Pinocy J

更新日期：2001-06-01 00:00:00

abstract：:Increasing evidence has demonstrated that the immune system closely interacts with other physiological systems, whose communications are mediated by circulating cytokines and hormones. The aim of our study was to test whether the number and cytolytic activity of NK cells in a group of relatively healthy Italian nonage...

journal_title：Clinical and experimental immunology

authors： Mariani E,Ravaglia G,Forti P,Meneghetti A,Tarozzi A,Maioli F,Boschi F,Pratelli L,Pizzoferrato A,Piras F,Facchini A

更新日期：1999-04-01 00:00:00

abstract：:Serum and salivary responses of 95 infants to either a standard (4 x 10(4) plaque-forming units (PFU), 47 neonates) or a high dose (4 x 10(5) PFU, 48 neonates) of tetravalent reassortant rhesus rotavirus vaccine (administered at 2 days and at 6 weeks of age) were evaluated in a double-blind clinical trial. Serum and s...

journal_title：Clinical and experimental immunology

authors： Friedman MG,Segal B,Zedaka R,Sarov B,Margalith M,Bishop R,Dagan R

更新日期：1993-05-01 00:00:00

abstract：:In order to investigate the T cell cytokine profile during age-dependent maturation of the immune response, we evaluated the cytokine expression of CD4+ and CD8+ circulating cells by flow cytometric single-cell analysis after non-specific stimulation in vitro in different age groups of normal individuals, from cord bl...

journal_title：Clinical and experimental immunology

authors： Krampera M,Vinante F,Tavecchia L,Morosato L,Chilosi M,Romagnani S,Zanolin ME,Pizzolo G

更新日期：1999-08-01 00:00:00

abstract：:We describe the usefulness of a fast (48-h) limiting dilution assay (LDA) for the enumeration of human alloreactive helper T lymphocytes (HTL) in the peripheral blood, in relation to histologically defined rejection grades after heart transplantation. HTL frequencies (HTLf) in pretransplant samples varied from patient...

journal_title：Clinical and experimental immunology

authors： Vaessen LM,Daane CR,Maat AP,Balk AH,Claas FH,Weimar W

更新日期：1999-12-01 00:00:00

abstract：:Tuberculosis (TB) is usually more severe in HIV-infected patients, and the immune derangement found in co-infected patients may differ from that in each isolated disease. Following mitogen stimulation of peripheral blood mononuclear cells (PBMC), interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha production...

journal_title：Clinical and experimental immunology

authors： de Castro Cunha RM,Kallas EG,Rodrigues DS,Nascimento Burattini M,Salomao R

更新日期：2005-06-01 00:00:00

abstract：:Binding of lymphocytes to human umbilical vein endothelial cells (EC) was quantitated by measuring adhesion of 51Cr labelled lymphocytes to endothelial cell monolayers and rosette formation between lymphocytes and EC in suspension. Mitogen stimulated human peripheral blood mononuclear cell culture supernatants and mix...

journal_title：Clinical and experimental immunology

authors： Yu CL,Haskard DO,Cavender D,Johnson AR,Ziff M

更新日期：1985-12-01 00:00:00

abstract：:Using the natural killer (NK) sensitive K562 cell line, enhanced NK cell cytotoxicity was demonstrable early in the course of acute hepatitis B while normal values were obtained in patients studied during convalescence. No evidence of enhanced NK activity was instead obtained in the course of acute non-A, non-B hepati...

journal_title：Clinical and experimental immunology

authors： Chemello L,Mondelli M,Bortolotti F,Schiavon E,Pontisso P,Alberti A,Rondanelli EG,Realdi G

更新日期：1986-04-01 00:00:00

abstract：:In patients with ANCA-associated vasculitis (AAV), CD25 expression is increased on circulating T cells. Although in animal experiments the role of CD4(+) CD25(+) T-regulatory-cells (T(reg)) in protection against autoimmunity is well established, the role of these cells in AAV is unknown. To investigate the hypothesis ...

journal_title：Clinical and experimental immunology

authors： Marinaki S,Neumann I,Kälsch AI,Grimminger P,Breedijk A,Birck R,Schmitt W,Waldherr R,Yard BA,Van Der Woude FJ

更新日期：2005-04-01 00:00:00

abstract：:In this study the antigen-presenting capacity of human peritoneal cells and the influence of continuous ambulant peritoneal dialysis (CAPD) were studied. On average 6% of the peritoneal cells were dendritic cells (DC), with no difference between CAPD and control peritoneal cells. DC were enriched by selecting for non-...

journal_title：Clinical and experimental immunology

authors： Betjes MG,Tuk CW,Struijk DG,Krediet RT,Arisz L,Beelen RH

更新日期：1993-11-01 00:00:00

abstract：:Peripheral blood B lymphocytes, depleted of adherent cells, from 10 patients with multiple myeloma were cultured in the presence of PWM with autologous or donor T lymphocytes. The results show that: (1) co-cultures with allogeneic T lymphocytes produced more plasma cells than those with autologous ones; (2) the kappa/...

journal_title：Clinical and experimental immunology

authors： Gobbi M,Caligaris-Cappio F,Campana D,Tazzari PL,Bergui L,Cavo M,Tura S

更新日期：1984-12-01 00:00:00

abstract：:The family of Toll-like receptors (TLRs) initiates innate immune responses, and Toll-like receptor 4 (TLR4) was considered to be an important player in the initiation and progression of atherosclerotic disease. The aim of the study was to investigate the expression of TLR4 on peripheral-blood mononuclear cells (PBMCs)...

journal_title：Clinical and experimental immunology

authors： Geng HL,Lu HQ,Zhang LZ,Zhang H,Zhou L,Wang H,Zhong RQ

更新日期：2006-02-01 00:00:00

abstract：:The kinetics and effects of in vivo spontaneous apoptosis and activation-induced cell death (AICD) upon CD4+ and CD8+ lymphocyte subsets and CD4 naive cell numbers were studied in HIV+ subjects with CD4 pretreatment values > 200/mm3, who were subsequently treated for 48 weeks with HAART alone or in combination with si...

journal_title：Clinical and experimental immunology

authors： Caggiari L,Zanussi S,Bortolin MT,D'andrea M,Nasti G,Simonelli C,Tirelli U,De Paoli P

更新日期：2000-04-01 00:00:00

abstract：:The mycobacterial antigens and the factors related to protection for the development of active tuberculosis are not known. In a natural model of tuberculosis, we studied 10 patients with active pulmonary tuberculosis (non-protective immune response) and 38 healthy household contacts (protective immune response). We te...

journal_title：Clinical and experimental immunology

authors： Torres M,Mendez-Sampeiro P,Jimenez-Zamudio L,Teran L,Camarena A,Quezada R,Ramos E,Sada E

更新日期：1994-04-01 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta) and prostaglandins (PG) regulate the cell-mediated immune response, so it has been proposed that they affect the progression of pulmonary tuberculosis. Here we report that the administration of soluble betaglycan, a potent TGF-beta antagonist, and niflumic acid, a PG synthesi...

journal_title：Clinical and experimental immunology

authors： Hernández-Pando R,Orozco-Esteves H,Maldonado HA,Aguilar-León D,Vilchis-Landeros MM,Mata-Espinosa DA,Mendoza V,López-Casillas F

更新日期：2006-05-01 00:00:00

abstract：:In vivo studies in rats demonstrated that the binding of a highly cationic antigen (cationized human IgG, pI greater than 9.5) to glomerular polyanion could be significantly reduced by prior application of a small polycation, protamine sulfate. The degree of inhibition was dose dependent and the highest dose used, 4 m...

journal_title：Clinical and experimental immunology

authors： Oite T,Shimizu F,Batsford SR,Vogt A

更新日期：1986-05-01 00:00:00

abstract：:Perivascular infiltrates of inflammatory cells are a hallmark of lesional skin in scleroderma. We have explored the potential for scleroderma fibroblasts to modulate mononuclear leucocyte migration across endothelial cell monolayers in tissue culture, and to regulate expression of endothelial cell adhesion molecules. ...

journal_title：Clinical and experimental immunology

authors： Denton CP,Shi-Wen X,Sutton A,Abraham DJ,Black CM,Pearson JD

更新日期：1998-11-01 00:00:00

abstract：:By immunological screening of a cDNA library derived from protoscoleces of Echinococcus granulosus with IgE from patients with cystic echinococcosis (CE) and allergic manifestations, we isolated a protein identical to E. granulosus cyclophilin. The protein, named EA21, has close homology with Malassezia furfur cycloph...

journal_title：Clinical and experimental immunology

authors： Ortona E,Vaccari S,Margutti P,Delunardo F,Rigano R,Profumo E,Buttari B,Rasool O,Teggi A,Siracusano A

更新日期：2002-04-01 00:00:00

abstract：:IL-4 synergizes with signals delivered through CD40 both for the induction of CD23/Fc epsilon RII expression and for IgE synthesis. Moreover, engagement of CD40 on the B cell surface by MoAb overcomes the ability of interferons, transforming growth factor-beta, or anti-CD19 to inhibit IL-4-dependent change. We now rep...

journal_title：Clinical and experimental immunology

authors： Katira A,Knox KA,Finney M,Michell RH,Wakelam M,Gordon J

更新日期：1993-05-01 00:00:00

abstract：:Lymphocytes from normal individuals with the histocompatibility antigens HLA-B8 and DR3 have impaired proliferative responses when stimulated with suboptimal concentrations of mitogens. We have previously shown that an important factor in the impaired response is a failure to produce normal quantities of interleukin-2...

journal_title：Clinical and experimental immunology

authors： Hashimoto S,Michalski JP,Berman MA,McCombs C

更新日期：1990-02-01 00:00:00

abstract：:Frozen sections of control and coeliac jejunal mucosa were examined for HLA-DR staining. In general the staining pattern in the controls and treated coeliac patients was a patchy subapical pattern on villous tips. Untreated coeliac patients gave a different pattern with staining extending to the crypt enterocytes. Glu...

journal_title：Clinical and experimental immunology

authors： Ciclitira PJ,Nelufer JM,Ellis HJ,Evans DJ

更新日期：1986-01-01 00:00:00

abstract：:To elucidate antibody recognition of DNA in normal and aberrant immunity, the binding of sera of normal human subjects (NHS) and patients with SLE was tested with mammalian and bacterial DNA varying in size. Klebsiella pneumoniae (KP) and calf thymus (CT) single-stranded DNA (ssDNA) were investigated as model antigens...

journal_title：Clinical and experimental immunology

authors： Pisetsky DS,Gonzalez TC

更新日期：1999-05-01 00:00:00

abstract：:It has been shown that bronchoalveolar lavages (BALs) from patients with sarcoidosis and other interstitial lung diseases contain abnormally increased numbers of alveolar macrophages (AM) expressing antigens found on monocytes. The aim of this study was to compare the phenotype of AM from patients with sarcoidosis wit...

journal_title：Clinical and experimental immunology

authors： Barbosa IL,Gant VA,Hamblin AS

更新日期：1991-10-01 00:00:00

abstract：:The lymphotoxin-beta receptor (LTbetaR) pathway is critical for maintenance of organized lymphoid structures and is involved in the development of colitis. To investigate the mechanisms by which LTbetaR activation contributes to the pathology of chronic inflammation we used a soluble LTbetaR-Ig fusion protein as a com...

journal_title：Clinical and experimental immunology

authors： Stopfer P,Obermeier F,Dunger N,Falk W,Farkas S,Janotta M,Möller A,Männel DN,Hehlgans T

更新日期：2004-04-01 00:00:00

abstract：:Oestradiol and the selective oestrogen receptor modulator (SERM) raloxifene have been shown to ameliorate collagen-induced arthritis (CIA) in rats and in mice. One aim was to investigate if raloxifene exerts its anti-arthritic and anti-osteoporotic effects during the induction or effector phase of arthritis. A second ...

journal_title：Clinical and experimental immunology

authors： Jochems C,Islander U,Erlandsson M,Engdahl C,Lagerquist M,Ohlsson C,Nandakumar KS,Holmdahl R,Carlsten H

更新日期：2011-07-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a persistent virus with oncogenic capacity that has been implicated in the development of aggressive B cell lymphomas, primarily in immunosuppressed individuals, although it can be present in immunocompetent individuals. Changes in the function and clonal diversity of T lymphocytes might be...

journal_title：Clinical and experimental immunology

authors： Cárdenas D,Vélez G,Orfao A,Herrera MV,Solano J,Olaya M,Uribe AM,Saavedra C,Duarte M,Rodríguez M,López M,Fiorentino S,Quijano S

更新日期：2015-11-01 00:00:00

abstract：:The expression in tissue and serum of a panel of murine and human common DNA antibody idiotypes (Ids) (BEG 2, PR 4, F-423, I-402, II-28, IV-228, V-88) has been investigated. The murine V-88 Id was detected in eight out of 10 and the human BEG 2 Id in five out of 10 labial biopsies from patients with Sjögren's syndrome...

journal_title：Clinical and experimental immunology

authors： Watts RA,Ravirajan CT,Wilkinson LS,Williams W,Griffiths M,Butcher D,Horsfall AT,Staines NA,Isenberg DA

更新日期：1991-02-01 00:00:00