A proposed ethical framework for interventional cognitive neuroscience: a consideration of deep brain stimulation in impaired consciousness.

abstract：BACKGROUND:Giant and large intracranial aneurysms represent enormous therapeutic challenges for neurosurgeons as well as for endovascular therapists. Since they may involve entire vessels or be irregular in shape, the rate of complete obliteration with GDCs is low and the incidence of recanalization is very high. So th...

journal_title：Neurological research

authors： Yang X,Wu Z,Mu S,Li Y,Lv M

更新日期：2008-07-01 00:00:00

abstract：:We describe the advantages and clarify the technical key points of a microendoscopic, minimally invasive technique to the posterior surgical approach for cervical degenerative disease. The authors studied the microendoscopic posterior approach using the METRx system in both cadaver models and in clinical cases. This n...

journal_title：Neurological research

authors： Yuguchi T,Nishio M,Akiyama C,Ito M,Yoshimine T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies have shown that awareness of early stroke symptoms and the use of ambulances are two important factors in decreasing pre-hospital stroke delay. The purpose of this study is to evaluate a comprehensive educational stroke protocol in improving stroke response times. METHOD:Two urban commun...

journal_title：Neurological research

authors： Chen S,Sun H,Zhao X,Fu P,Yan W,Yilong W,Hongyan J,Yan Z,Wenzhi W

更新日期：2013-06-01 00:00:00

abstract：:This study was designed to assess the effects of volume expansion with Fluosol-DA and hetastarch on local cerebral blood flow (CBF), cortical O2 availability (O2a) and computerized EEG power data during cerebral ischaemia in a primate stroke model. Focal cerebral ischaemia was produced in 20 anaesthetized Macaca monke...

journal_title：Neurological research

authors： Tranmer BI,Iacobacci R,Feiler S

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Previous reports showed the reduction of dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease. In this work, we sought to investigate the possible correlation between central and peripheral dopamine transporter immunoreactivity values in a group of 11 drug-naive patient...

journal_title：Neurological research

authors： Buttarelli FR,Capriotti G,Pellicano C,Prosperi D,Circella A,Festa A,Giovannelli M,Tofani A,Pontieri FE,Scopinaro F

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:Neurotoxic homocysteine (Hcy) is thought to be an independent risk factor for neurodegenerative diseases, including Alzheimer's disease. This study is to determine whether HT22 cells, a murine hippocampal neuronal model, can be used as an in vitro model, besides the primary neuronal cultures, to investiga...

journal_title：Neurological research

authors： Zhao Z,Lu R,Zhang B,Shen J,Yang L,Xiao S,Liu J,Suo WZ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：:This paper summarizes the work of developing and analyzing a mathematical model of schizophrenia. First the psychological and physiological studies of patients with periodic catatonia made by R. R. Gjessing are briefly described. Then a mathematical model, which is based on Gjessing's work and consists of a set of non...

journal_title：Neurological research

authors： Cronin J

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...

journal_title：Neurological research

authors： Zhu H,Li Z,Lv J,Zhao R

更新日期：2018-05-01 00:00:00

abstract：:Six cases of very large anterior circulation intracranial aneurysms are presented. Aneurysms of 53-84 mm in three female and two male adults and a 40 mm lesion in a seven week infant were successfully excised. Three patients tolerated trial intraluminal balloon occlusion preoperatively and underwent subsequent parent ...

journal_title：Neurological research

authors： Cahill DW

更新日期：1992-01-01 00:00:00

abstract：:The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

journal_title：Neurological research

authors： Rabinovsky ED

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:Tissue plasminogen activator (tPA) may aggravate ischemic neuronal damage after focal cerebral ischemia and increase blood-brain barrier permeability. Human serum albumin has neuroprotective effects on ischemic stroke. However, whether albumin can attenuate the deleterious effects of tPA is yet unknown. METH...

journal_title：Neurological research

authors： Tang J,Li YJ,Mu J,Li Q,Yang DY,Xie P

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:It is difficult for the treatment of neurologic tumors with current therapies, including glioma. Despite the advances in cancer therapeutics, the outcomes in these patients remain poor and, therefore, new modalities are required. Recent findings have demonstrated that human umbilical cord blood mesenchymal st...

journal_title：Neurological research

authors： Jiao H,Yang B,Guan F,Li J,Shan H,Song L,Hu X,Liang S,Du Y,Jiang C

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To explore the value of dynamically monitored levels of plasma prothrombin fragment(1+2) (F(1+2)) and D-dimer in the process of thrombolysis with urokinase. METHODS:Blood samples were collected at baseline and at hours 1, 2, 3, 6, 12, 24, 48, 72, and 96 after urokinase infusion finished. The levels of plasma...

journal_title：Neurological research

authors： Meng R,Ji X,Li B,Zhou J,Li W,Ding Y

更新日期：2009-05-01 00:00:00

abstract：:Regional CBF was measured by 133Xe inhalation in unilateral cerebral infarction, carotid TIAs, and normal volunteers. Regional CBF values were bilaterally and symmetrically reduced in patients measured within 3 weeks after stroke. Later, rCBF values returned toward normal in the contralateral hemisphere of patients wi...

journal_title：Neurological research

authors： Meyer JS,Naritomi H,Sakai F,Ishihara N,Grant P

更新日期：1979-01-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of nicardipine prolonged-release implants for preventing vasospasm in a canine SAH model in a dose-escalating placebo-controlled blind fashion. Drug-release kinetics of copoly(lactic/glycolic acid) pellet containing nicardipine were evaluated in vitro. In vivo, 1...

journal_title：Neurological research

authors： Kawashima A,Kasuya H,Sasahara A,Miyajima M,Izawa M,Hori T

更新日期：2000-09-01 00:00:00

abstract：:Corticotrophin releasing factor has been shown in several models of tissue injury to be an effective treatment for edema. In a previous study we demonstrated this ability in two models of traumatic brain injury (TBI). The aim of this study was to assess whether human corticotrophin releasing factor (hCRF) could additi...

journal_title：Neurological research

authors： Beaumont A,Marmarou C,Marmarou A

更新日期：2000-10-01 00:00:00

abstract：:We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

journal_title：Neurological research

authors： Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

更新日期：2002-03-01 00:00:00

abstract：:Mountain trekking is significantly increasing in popularity. Hypoxia seems to play a key role in the pathogenesis of acute mountain sickness (AMS). The purpose of this study was to investigate regional cerebral (rSO2) and peripheral (SaO2) oxygen saturation for the first time, during 22 days high altitude trekking (me...

journal_title：Neurological research

authors： Hadolt I,Litscher G

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine the functional abnormalities of the Leu89Pro mutation in connexin32 (CX32), which we have previously reported is present within an X-linked dominant Charcot-Marie-Tooth disease family. In this family, male patients were moderately to severely affected. METHODS:We performed immunofluorescence to ...

journal_title：Neurological research

authors： Da Y,Wang W,Liu Z,Chen H,Di L,Previch L,Chen Z

更新日期：2016-10-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...

journal_title：Neurological research

authors： Dedic SI,Stevic Z,Dedic V,Stojanovic VR,Milicev M,Lavrnic D

更新日期：2012-07-01 00:00:00

abstract：:To investigate the migration of neural stem cells as well as neural plastic changes in epileptic brain, spaciotemporal expression of immunoreactive highly polysialylated neural cell adhesion molecule (PSA-NCAM) was examined in amygdala kindling development of rat. The neural migration and synaptic remodeling detected ...

journal_title：Neurological research

authors： Sato K,Iwai M,Nagano I,Shoji M,Abe K

更新日期：2003-01-01 00:00:00

abstract：:The effects of long-term administration of fructose-added glycerol solution (Glyceol): 10% glycerol, 5% fructose, 0.9% sodium chloride; 600-2000 ml/d intravenously for 7-63 d) were evaluated in a multi-institutional trial involving 1346 cases. Improvement of the neurological signs and symptoms of elevated intracranial...

journal_title：Neurological research

authors： Tsubokawa T,Katayama Y,Ishii S

更新日期：1989-12-01 00:00:00

abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...

journal_title：Neurological research

authors： Nagasawa S,Kawanishi M,Tanaka H,Ohta T,Nagayasu S,Kikuchi H

更新日期：1993-12-01 00:00:00

abstract：:Our aim was to evaluate the relationship between the neurological outcome of tuberous sclerosis complex (TSC) and the findings obtained from both cranial magnetic resonance imaging (MRI) and single voxel proton spectroscopy (SVPS). MRIs of 13 children who met the diagnostic criteria for TSC were taken. Eleven of these...

journal_title：Neurological research

authors： Yapici Z,Dörtcan N,Baykan BB,Okan F,Dinçer A,Baykal C,Eraksoy M,Roach S

更新日期：2007-07-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To explore the risk factors for stroke-associated pneumonia (SAP). METHODS:A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009. RESULTS:A multi...

journal_title：Neurological research

authors： Sui R,Zhang L

更新日期：2011-06-01 00:00:00

abstract：:The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the...

journal_title：Neurological research

authors： Tanaka R,Miyasaka Y,Maruyama S,Nagai S,Fujii K

更新日期：1996-08-01 00:00:00

abstract：:Recent studies suggest that high plasma levels of tissue-type plasminogen activator (tPA) and its inhibitor (plasminogen activator inhibitor-1, PAI-1) are markers of an increased risk of atherothrombotic ischemic events such as stroke and myocardial infarction. In this prospective study, we measured tPA antigen, PAI-1...

journal_title：Neurological research

authors： Zunker P,Schick A,Padró T,Kienast J,Phillips A,Ringelstein EB

更新日期：1999-12-01 00:00:00

abstract：:We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...

journal_title：Neurological research

authors： Kalback W,Esh C,Castaño EM,Rahman A,Kokjohn T,Luehrs DC,Sue L,Cisneros R,Gerber F,Richardson C,Bohrmann B,Walker DG,Beach TG,Roher AE

更新日期：2004-07-01 00:00:00