Tissue plasminogen activator and plasminogen activator inhibitor in patients with acute ischemic stroke: relation to stroke etiology.

abstract：OBJECTIVE:The aim of this report was to set up an effective experimental model of cocultures between cells from spinal cord explants and myotubes from adductor muscle. METHODS:We obtained neuronal cells from chick spinal cord explants at embryonic day 5 (ED5) by means of an enzymatic digestion. Small spinal cord fragm...

journal_title：Neurological research

authors： Martinello T,Patruno M

更新日期：2008-03-01 00:00:00

abstract：:Background: IVS5-91G>A (rs3812718) polymorphism of the sodium voltage-gated channel alpha subunit 1 (SCN1A) gene has been associated with inadequate responsiveness to common antiepileptic drugs which act as sodium channel blockers. This study was performed to investigate the effect of IVS5-91G>A (rs3812718) polymorphi...

journal_title：Neurological research

authors： Markovic I,Pejanovic-Skobic N,Bozina N,Susak Sporis I,Sporis D,Basic S

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:Surgical management of tumors in the sacropelvic region is a challenging field of spine surgery because of the region's complex local anatomy and biomechanics. Recent developments in anesthesia and intensive care have allowed us to perform extended surgeries focused on the en bloc resection of sacropelvic tu...

journal_title：Neurological research

authors： Varga PP,Szoverfi Z,Lazary A

更新日期：2014-06-01 00:00:00

abstract：:The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...

journal_title：Neurological research

authors： Robertson J,Timmons S

更新日期：2007-10-01 00:00:00

abstract：OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

journal_title：Neurological research

authors： Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

更新日期：2017-09-01 00:00:00

abstract：:Electrical stimulation of peripheral nerves can be used to cause muscle contraction, to activate reflexes, and to modulate some functions of the central nervous system (neuromodulation). If applied to the spinal cord or nerves controlling the lower urinary tract, electrical stimulation can produce bladder or sphincter...

journal_title：Neurological research

authors： Jezernik S,Craggs M,Grill WM,Creasey G,Rijkhoff NJ

更新日期：2002-07-01 00:00:00

abstract：:Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

journal_title：Neurological research

authors： Droste DW,Sonne M,Siemens HJ,Kaps M

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Spinal cord injury (SCI) causes muscle atrophy, which is particularly severe, due to inability to perform tetanic contractions, when lower motor neurons (LMN) are involved. We performed a longitudinal study in 25 Europeans suffering from complete conus cauda syndrome from 0.7 to 8.7 years comparing functional...

journal_title：Neurological research

authors： Kern H,Carraro U,Adami N,Hofer C,Loefler S,Vogelauer M,Mayr W,Rupp R,Zampieri S

更新日期：2010-02-01 00:00:00

abstract：:The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...

journal_title：Neurological research

authors： Mizoguchi K

更新日期：1998-10-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of nicardipine prolonged-release implants for preventing vasospasm in a canine SAH model in a dose-escalating placebo-controlled blind fashion. Drug-release kinetics of copoly(lactic/glycolic acid) pellet containing nicardipine were evaluated in vitro. In vivo, 1...

journal_title：Neurological research

authors： Kawashima A,Kasuya H,Sasahara A,Miyajima M,Izawa M,Hori T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Infection is a major complication and risk factor of cerebrospinal fluid (CSF) shunting procedures. Recently, antibiotic-impregnated shunt systems have been developed in an attempt to prevent or reduce the CSF infection. The aim of this study was to determine the efficacy of silver-impregnated polyurethane ve...

journal_title：Neurological research

authors： Izci Y,Secer H,Akay C,Gonul E

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:To find new biomarkers by stimulating acupuncture point GB34 (Yangneungcheon) which has neuroprotective effect on the mouse model of Parkinson's disease, analysis of cDNA microarray on mRNAs of the substantia nigra was performed. METHODS:Male C57BL/6 mice were divided into two groups: 1-methyl-4-phenyl-1,2,...

journal_title：Neurological research

authors： Hong MS,Park HK,Yang JS,Park HJ,Kim ST,Kim SN,Park JY,Song JY,Park HK,Jo DJ,Park SW,HwanYun D,Ban JY,Chung JH

更新日期：2010-02-01 00:00:00

abstract：:It was predicted, based on a mathematical model of the cortex, that early music training would enhance spatial-temporal reasoning. We have demonstrated that preschool children given six months of piano keyboard lessons improved dramatically on spatial-temporal reasoning while children in appropriate control groups did...

journal_title：Neurological research

authors： Graziano AB,Peterson M,Shaw GL

更新日期：1999-03-01 00:00:00

abstract：:Ahead of Print article withdrawn by publisher. ...

journal_title：Neurological research

authors： Ma CX,Yin WN,Cai BW,He M,Wu J,Wang JY,Zeng Y,Ding JL,You C

更新日期：2009-08-21 00:00:00

abstract：:Parkinson's disease (PD) the second most common age-associated progressive neurodegenerative disorder is characterized by loss of dopaminergic neurons, cytoplasmic inclusions of aggregated proteins (Lewy bodies), and neuroinflammation. The inflammation of neurons causes release of various inflammatory mediators (IFNs,...

journal_title：Neurological research

authors： Pal R,Tiwari PC,Nath R,Pant KK

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Alteration of sensorium or an encephalopathy is a common diagnostic dilemma in critically ill patients and can be caused by a number of conditions. Sepsis associated encephalopathy (SAE) is now the most common encephalopathy encountered among intensive care unit (ICU) patients. DEFINITIONS:SAE is an encep...

journal_title：Neurological research

authors： Maramattom BV

更新日期：2007-10-01 00:00:00

abstract：:Because clinicians require objectively demonstrable neurological deficits to confirm a diagnosis, the recognition of embolic events in the nervous system is generally restricted to the effects of ischemic necrosis produced by arterial occlusion. However, magnetic resonance imaging (MRI) has shown that lesser degrees o...

journal_title：Neurological research

authors： James PB

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Venous compression might be the main cause of incomplete decompression and symptom recurrence after microvascular decompression (MVD) in patients with trigeminal neuralgia. Although it can be killed in most cases, cutting the vein sometimes has the potential risk arising from venous congestion. To maneuver th...

journal_title：Neurological research

authors： Zhong J,Li ST,Xu SQ,Wan L,Wang X

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G...

journal_title：Neurological research

authors： Jafarian Z,Saliminejad K,Kamali K,Ohadi M,Kowsari A,Nasehi L,Khorram Khorshid HR

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The amyloid hypothesis stimulates the discovery of compounds, which promotes beta-amyloid peptide (Aβ) clearance, thereby altering the underlying pathophysiology of Alzheimer's disease (AD). Hence, the present study aims at the evaluation of anti-amyloidogenic potential of Gelidiella acerosa. METHODS:Prevent...

journal_title：Neurological research

authors： Syad AN,Devi KP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Numerous studies have identified different predictors for secondary hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH), although predictors regarding timing of the shunt operation have never been reported. Predictors for an early shunt, which was defined as a shunt operation performed ≤30 days after...

journal_title：Neurological research

authors： Shigematsu H,Sorimachi T,Osada T,Aoki R,Srivatanakul K,Oda S,Matsumae M

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:One of the main obstacles of electrode implantation in epilepsy surgery is the electrode shift between implantation and the day of explantation. We evaluated this possible electrode displacement using intraoperative MRI (iopMRI) data and CT/MRI reconstruction. METHODS:Thirteen patients (nine female, four ma...

journal_title：Neurological research

authors： Sommer B,Rampp S,Doerfler A,Stefan H,Hamer HM,Buchfelder M,Roessler K

更新日期：2018-10-01 00:00:00

abstract：:In 75 patients with completed stroke hypervolemic haemodilution was performed for 1 day with 500 ml 6% HES 200.000/0.6-0.66 (Elohäst) to test the acute influence of application time for haemorheological changes. The patients were divided into 3 groups randomly selected: group A received the infusion for 2 hours, group...

journal_title：Neurological research

authors： Költringer P,Langsteger W,Reisecker F,Eber O

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION:The novel coronavirus disease (COVID-19) pandemic poses a substantial threat to the health of healthcare personnel on the front line of caring for COVID-19 patients. The Centers for Medicare and Medicaid Services previously announced that all non-essential planned surgeries and procedures should be postpon...

journal_title：Neurological research

authors： Reed LK,Wen J,Liang B,Wang X,Feng D,Huang JH

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Diabetes is one of the major risk factors for ischemic stroke and is reported to aggravate the ischemic brain damage in different experimental models as well as clinical situations. However, the mechanisms underlying the exacerbated ischemia/reperfusion (I/R) brain injury associated with comorbid diabetes ar...

journal_title：Neurological research

authors： Srinivasan K,Sharma SS

更新日期：2011-10-01 00:00:00

abstract：:Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...

journal_title：Neurological research

authors： Couldwell WT,Zhang W,Allen R,Arce D,Stillerman CB

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical application of adjuvant coiling techniques in treating anterior-circulation wide-necked aneurysms. METHODS:Over 4·5 years, 93 anterior-circulation wide-neck aneurysms in 81 patients were treated with different endovascular techniques: balloon-assisted, stent-assisted, and double-m...

journal_title：Neurological research

authors： Pan J,Xiao F,Szeder V,Yan M,Fan W,Gu J,He L,Zhan R

更新日期：2013-12-01 00:00:00

abstract：:It is known that mitochondrial ATP-sensitive potassium channels (mitoKATP) play a significant role in protecting cerebral function from ischemia-reperfusion injury, which is related with a decrease in the mitochondrial matrix calcium. However, the effect of mitochondrial calcium uniporter (MCU) on diazoxide-induced ce...

journal_title：Neurological research

authors： Zhang L,Wang S,Dong H,Li Y,Wang P,Li S,Guo Y,Yao R

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Neuropsychological outcomes after carotid endarterectomy (CEA) have been investigated extensively. However, cognitive impacts of carotid angioplasty and stenting (CAS), an emerging alternative to CEA, have not been studied. This study is aimed at investigating pattern and degree of cognitive changes after CAS...

journal_title：Neurological research

authors： Xu G,Liu X,Meyer JS,Yin Q,Zhang R

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China. SUBJECTS AND METHODS:A cross-sectional study (across 19 urban outpatient clinics) on secondary stroke prevention measures w...

journal_title：Neurological research

authors： Wang Y,Wu D,Zhou Y,Zhao X,Wang C,Liu L,Liao X,Wang Y

更新日期：2008-05-01 00:00:00