Survival and function of bioengineered cardiac grafts.

abstract：:Real-time cross-sectional echocardiographic studies of the main coronary arteries were performed in 20 normal subjects, 12 patients with patent ductus arteriosus and 14 patients with coronary artery fistula in whom the diagnosis was established by angiography. In 12 patients, the coronary artery that formed the fistul...

journal_title：Circulation

authors： Yoshikawa J,Katao H,Yanagihara K,Takagi Y,Okumachi F,Yoshida K,Tomita Y,Fukaya T,Baba K

更新日期：1982-03-01 00:00:00

abstract：:Global ventricular function was evaluated by both multiple gated cardiac blood pool scans (MUGA) and contrast ventriculograms in a group of 17 patients with suspected coronary artery disease. The contrast ventriculograms were analyzed frame by frame to generate a volume versus time curve for each patient, while the tr...

journal_title：Circulation

authors： Burow RD,Strauss HW,Singleton R,Pond M,Rehn T,Bailey IK,Griffith LC,Nickoloff E,Pitt B

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Recent studies indicate that serotonin (5-HT) has a growth-promoting effect on several different cell types, including smooth muscle cells. After percutaneous transluminal coronary angioplasty, there is damage and denudation of vascular endothelial cells, which promotes platelet aggregation at the site of in...

journal_title：Circulation

authors： Pakala R,Willerson JT,Benedict CR

更新日期：1994-10-01 00:00:00

abstract：:High-density lipoprotein (HDL) cholesterol distributions were compared among 191 black and 1341 white males and 233 black and 1088 white females, ages 5-44 years, examined in five of the Lipid Research Clinic (LRC) population-based surveys. Mean HDL cholesterol was higher in blacks than whites in each 5-year age group...

journal_title：Circulation

authors： Tyroler HA,Glueck CJ,Christensen B,Kwiterovich PO Jr

更新日期：1980-11-01 00:00:00

abstract：:The left anterior descending coronary artery of four dogs and the right common carotid artery of 15 rabbits were subjected to 40-60% reduction in transluminal diameter for 1 hour by partial ligation with suture thread. Scanning electron microscopic examination of the luminal surface of these vessels revealed endotheli...

journal_title：Circulation

authors： Gertz SD,Uretsky G,Wajnberg RS,Navot N,Gotsman MS

更新日期：1981-03-01 00:00:00

abstract：:To determine whether real-time two-dimensional echocardiography (2-D echo) can estimate the extent of myocardial involvement in patients with acute myocardial infarction (MI), regional wall motion on serial short-axis 2-D echo recordings was analyzed and the summed scores were compared with estimates of infarct involv...

journal_title：Circulation

authors： Nixon JV,Narahara KA,Smitherman TC

更新日期：1980-12-01 00:00:00

abstract：:Background: In ISCHEMIA, an initial invasive strategy did not significantly reduce rates of cardiovascular events or all-cause mortality compared with a conservative strategy in patients with stable ischemic heart disease and moderate/severe myocardial ischemia. The most frequent component of composite cardiovascular ...

journal_title：Circulation

authors： Chaitman BR,Alexander KP,Cyr DD,Berger JS,Reynolds HR,Bangalore S,Boden WE,Lopes RD,Demkow M,Perna GP,Riezebos RK,McFalls EO,Banerjee S,Bagai A,Gosselin G,O'Brien SM,Rockhold FW,Waters DD,Thygesen KA,Stone GW,Whit

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Femoropopliteal percutaneous transluminal angioplasty (PTA) remains limited by restenosis. Although vascular brachytherapy may be effective in reducing restenosis, external beam radiation would be more practical to administer after PTA. METHODS AND RESULTS:After femoropopliteal PTA without stent placement, ...

journal_title：Circulation

authors： Therasse E,Donath D,Lespérance J,Tardif JC,Guertin MC,Oliva VL,Soulez G

更新日期：2005-06-21 00:00:00

abstract：BACKGROUND:To identify patients at risk for postoperative myocardial injury and death, measuring cardiac troponin routinely after noncardiac surgery has been suggested. Such monitoring was implemented in our hospital. The aim of this study was to determine the predictive value of postoperative myocardial injury, as mea...

journal_title：Circulation

authors： van Waes JA,Nathoe HM,de Graaff JC,Kemperman H,de Borst GJ,Peelen LM,van Klei WA,Cardiac Health After Surgery (CHASE) Investigators.

更新日期：2013-06-11 00:00:00

abstract：:To assess the effects on the heart itself of coronary thrombolysis induced with either tissue-type plasminogen activator (t-PA) or streptokinase (SK), we performed positron emission tomography with 11C-palmitate in 19 patients with initial transmural myocardial infarction immediately after admission and again within 4...

journal_title：Circulation

authors： Sobel BE,Geltman EM,Tiefenbrunn AJ,Jaffe AS,Spadaro JJ Jr,Ter-Pogossian MM,Collen D,Ludbrook PA

更新日期：1984-05-01 00:00:00

abstract：:As part of two Department of Veterans Affairs Cooperative Trials, we obtained angiographic patency data for internal mammary artery (IMA) and saphenous vein grafts to the left anterior descending (LAD) coronary artery at 1 year after coronary artery bypass surgery. Patients received either aspirin 325 mg q.d., aspirin...

journal_title：Circulation

authors： Goldman S,Copeland J,Moritz T,Henderson W,Zadina K,Ovitt T,Kern KB,Sethi G,Sharma GV,Khuri S

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Several clinical studies have demonstrated a general superiority of biphasic waveform defibrillation compared with monophasic waveform defibrillation using epicardial lead systems. To test the breadth of utility of biphasic waveforms in humans, a prospective, randomized evaluation of defibrillation efficacy ...

journal_title：Circulation

authors： Bardy GH,Troutman C,Johnson G,Mehra R,Poole JE,Dolack GL,Kudenchuk PJ,Gartman DM

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase (COX)-2 contributes to vascular smooth muscle cell (VSMC) proliferation induced by tumor necrosis factor (TNF) and angiotensin II. The present study demonstrates, however, that depending on prevailing conditions, COX-2-derived prostanoids may also inhibit VSMC proliferation. METHODS AND RESUL...

journal_title：Circulation

authors： Haider A,Lee I,Grabarek J,Darzynkiewicz Z,Ferreri NR

更新日期：2003-08-26 00:00:00

abstract：:Labetalol was administered to six hypertensive subjects in increasing doses for seven days. A decrease in both supine and standing arterial pressure and heart rate was observed with no change in cardiac output and few side effects. Exercise tolerance was unaltered by the drug, but the heart rate and arterial pressure ...

journal_title：Circulation

authors： Mehta J,Cohn JN

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Matricellular proteins are extracellular matrix proteins that do not contribute directly to tissue integrity but are capable of modulating cell function. We hypothesized that the matricellular protein thrombospondin (TSP)-1, a potent inhibitor of angiogenesis and activator of transforming growth factor (TGF-...

journal_title：Circulation

authors： Frangogiannis NG,Ren G,Dewald O,Zymek P,Haudek S,Koerting A,Winkelmann K,Michael LH,Lawler J,Entman ML

更新日期：2005-06-07 00:00:00

abstract：BACKGROUND:The Na+-H+ exchanger figures prominently in cardiac ischemia-reperfusion injury. Several experimental and clinical studies have demonstrated a cardioprotective effect of Na+-H+ exchanger inhibition; however, the precise mechanisms have not been established. METHODS AND RESULTS:We examined the effects of car...

journal_title：Circulation

authors： Teshima Y,Akao M,Jones SP,Marbán E

更新日期：2003-11-04 00:00:00

abstract：BACKGROUND:Endothelial dysfunction of coronary arteries with impaired vasodilation has been reported in patients with arterial hypertension. However, the effect of dynamic exercise on coronary vasomotion of a stenotic vessel segment before and after PTCA has not yet been evaluated in these patients. METHODS AND RESULT...

journal_title：Circulation

authors： Frielingsdorf J,Kaufmann P,Suter T,Hug R,Hess OM

更新日期：1998-09-22 00:00:00

abstract：BACKGROUND:The excess risk of atherosclerosis among patients with non-insulin dependent diabetes mellitus (NIDDM) is well documented. However, the presence of conventional risk factors cannot fully account for this excess risk, and the underlying mechanism remains to be elucidated. The present study prospectively evalu...

journal_title：Circulation

authors： Austin MA,Mykkänen L,Kuusisto J,Edwards KL,Nelson C,Haffner SM,Pyörälä K,Laakso M

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Previous studies comparing off-pump coronary artery bypass surgery (OPCABG) to conventional techniques utilizing cardiopulmonary bypass (CABG-CPB) have failed to provide patient selection guidelines. We sought to determine guidelines, attempting to rectify the limitations of previous studies. METHODS AND RES...

journal_title：Circulation

authors： Magee MJ,Coombs LP,Peterson ED,Mack MJ

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:Sudden cardiac death in children is a rare but devastating event. Experts have debated the merits of community-based screening programs using an ECG and targeting 2 potential high-risk groups: school-aged children initiating stimulant medications to treat attention-deficit/hyperactivity disorder and adolesce...

journal_title：Circulation

authors： Leslie LK,Cohen JT,Newburger JW,Alexander ME,Wong JB,Sherwin ED,Rodday AM,Parsons SK,Triedman JK

更新日期：2012-05-29 00:00:00

abstract：:Diseases that cause symptoms incompletely relieved by available modes of treatment stimulate search for new therapies. Chronic disease processes, in which interventions are palliative rather than curative provide a particular challenge in determining the value of therapeutic intervention. Management of patients with a...

journal_title：Circulation

authors： Parisi AF,Strauss WE,McIntyre KM,Sasahara AA

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Carotid artery stenting (CAS) has recently emerged as a potential alternative to carotid endarterectomy. Cerebral embolization is the most devastating complication of CAS, and the echogenicity of carotid plaque has been indicated as one of the risk factors involved. This is the first study to analyze the rol...

journal_title：Circulation

authors： Biasi GM,Froio A,Diethrich EB,Deleo G,Galimberti S,Mingazzini P,Nicolaides AN,Griffin M,Raithel D,Reid DB,Valsecchi MG

更新日期：2004-08-10 00:00:00

abstract：BACKGROUND:Endothelial progenitor cells (EPCs) circulate in adult peripheral blood (PB) and contribute to neovascularization. However, little is known regarding whether EPCs and their putative precursor, CD34-positive mononuclear cells (MNC(CD34+)), are mobilized into PB in acute ischemic events in humans. METHODS AND...

journal_title：Circulation

authors： Shintani S,Murohara T,Ikeda H,Ueno T,Honma T,Katoh A,Sasaki K,Shimada T,Oike Y,Imaizumi T

更新日期：2001-06-12 00:00:00

abstract：BACKGROUND:Compared with single-chamber ventricular pacing, dual-chamber pacing can reduce adverse events and, as a result, improve quality of life in patients paced for sick sinus syndrome. It is not clear, however, how these benefits compare with the increased cost of dual-chamber pacemakers. METHODS AND RESULTS:We ...

journal_title：Circulation

authors： Rinfret S,Cohen DJ,Lamas GA,Fleischmann KE,Weinstein MC,Orav J,Schron E,Lee KL,Goldman L

更新日期：2005-01-18 00:00:00

abstract：BACKGROUND:Several individual pharmacological agents, such as antiplatelet drugs, beta-blockers, ACE inhibitors, and lipid-lowering agents, have proven efficacy in reducing mortality in patients with acute coronary syndromes. However, the impact of the combination of these agents on clinical outcomes has not been studi...

journal_title：Circulation

authors： Mukherjee D,Fang J,Chetcuti S,Moscucci M,Kline-Rogers E,Eagle KA

更新日期：2004-02-17 00:00:00

abstract：BACKGROUND:An estimated 275,000 patients undergo heart valve replacement each year. However, existing solutions for valve replacement are complicated by the morbidity associated with lifelong anticoagulation of mechanical valves and the limited durability of bioprostheses. Recent advances in tissue engineering and our ...

journal_title：Circulation

authors： Sutherland FW,Perry TE,Yu Y,Sherwood MC,Rabkin E,Masuda Y,Garcia GA,McLellan DL,Engelmayr GC Jr,Sacks MS,Schoen FJ,Mayer JE Jr

更新日期：2005-05-31 00:00:00

abstract：:A new technology, leadless pacemaker therapy, was recently introduced clinically to address lead- and pocket-related complications in conventional transvenous pacemaker therapy. These leadless devices are self-contained right ventricular single-chamber pacemakers implanted by using a femoral percutaneous approach. In ...

journal_title：Circulation

authors： Tjong FV,Reddy VY

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:The angiogenic function of endothelial cells is regulated by numerous mechanisms, but the impact of long noncoding RNAs (lncRNAs) has hardly been studied. We set out to identify novel and functionally important endothelial lncRNAs. METHODS:Epigenetically controlled lncRNAs in human umbilical vein endothelia...

journal_title：Circulation

authors： Leisegang MS,Fork C,Josipovic I,Richter FM,Preussner J,Hu J,Miller MJ,Epah J,Hofmann P,Günther S,Moll F,Valasarajan C,Heidler J,Ponomareva Y,Freiman TM,Maegdefessel L,Plate KH,Mittelbronn M,Uchida S,Künne C,Stello

更新日期：2017-07-04 00:00:00

abstract：BACKGROUND:The myocardial protective role of heat shock protein (HSP) has been demonstrated, and there has been increasing interest in stress response in the heart. We examined the DNA-binding activity of heat shock transcription factor (HSF), by which the transcription of heat shock genes is mainly regulated, during h...

journal_title：Circulation

authors： Nishizawa J,Nakai A,Higashi T,Tanabe M,Nomoto S,Matsuda K,Ban T,Nagata K

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Endurance athletes have higher high density lipoprotein (HDL) concentrations than sedentary controls. To examine the mechanism for this effect, we compared HDL apoprotein metabolism in 10 endurance athletes aged 34 +/- 6 years (mean +/- SD) and 10 sedentary men aged 36 +/- 8 years. METHODS AND RESULTS:Subje...

journal_title：Circulation

authors： Thompson PD,Cullinane EM,Sady SP,Flynn MM,Chenevert CB,Herbert PN

更新日期：1991-07-01 00:00:00