Abstract:
:A clinical study was conducted to determine the efficacy of terbinafine cream in severe cases of tinea pedis. The subjects were 21 men, members of the Japanese Self-Defense Forces who were judged to have severe symptoms of tinea pedis. The description 'severe' was defined as 'considered to require the concurrent internal administration of antifungals for complete cure', or as meeting criterion 5 or 6 for the severity of tinea pedis. A simple surface application of terbinafine cream was given once daily, the subjects' clinical manifestations, mycological cure rates and safety-related changes were observed, and a final assessment was made in the 12th week. In the final assessment, the improvement rate of the cutaneous symptoms was 95.2%, and the fungal eradication and efficacy rates were 81.0%. As for side-effects, one patient complained of local irritation. These results suggested that terbinafine cream is a beneficial topical antifungal cream for severe tinea pedis.
journal_name
Mycosesjournal_title
Mycosesauthors
Noguchi H,Hiruma M,Kawada Adoi
10.1046/j.1439-0507.1999.00487.xsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
479-84issue
7-8eissn
0933-7407issn
1439-0507journal_volume
42pub_type
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