Abstract:
:A 29-year-old female suffering from full-blown AIDS received fluconazole 400 mg day-1 for a long period for treatment of oral candidosis, pseudomembranous type. She had previously received this drug repeatedly for the same reason, yet manifest disease persisted. She was therefore put on parenteral amphotericin B, which led to clinical, but not mycological, cure in the short term. IC30 testing revealed a minimum inhibitory concentration (MIC) > 128 micrograms ml-1 for fluconazole. The isolate, however, was susceptible in vitro to ketoconazole, itraconazole and amphotericin B. The same antimicrobial susceptibility pattern was found with a second isolate obtained later. Resistance to fluconazole might become a major problem in HIV-infected patients receiving this drug for long periods.
journal_name
Mycosesjournal_title
Mycosesauthors
Thomas-Greber E,Korting HC,Bogner J,Goebel FDdoi
10.1111/j.1439-0507.1994.tb00282.xsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
35-8issue
1-2eissn
0933-7407issn
1439-0507journal_volume
37pub_type
杂志文章相关文献
MYCOSES文献大全abstract:BACKGROUND:Histoplasmosis is a frequent fungal infection in HIV/AIDS patients, with high morbimortality rates when diagnosis and treatment are delayed. Antibody detection, which is faster than the gold standard culture test, hastens the laboratory investigation. OBJECTIVES:To evaluate the role of WB for antibody detec...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12877
更新日期:2019-03-01 00:00:00
abstract::Ultraviolet B light (UVB) can have negative phototropic effects on fungi. Candida albicans is often found on human skin exposed to UVB. Therefore, it is of medical interest to know whether a negative phototropic response to UVB irradiation can support an invasive growth of this potentially dangerous agent. In our stud...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2005.01169.x
更新日期:2006-01-01 00:00:00
abstract::In the present study, we evaluated the occurrence of Malassezia spp. from superficial areas (ear, anus, forehead and back) in 100 healthy pigs. All cultures from anus, forehead and back were negative for Malassezia spp. A total of 73% of pigs were colonized by Malassezia yeasts in the external ear canals. We isolated ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2004.01048.x
更新日期:2005-01-01 00:00:00
abstract::The aim of this study was to genotype Candida albicans strains isolated from patients with invasive and non-invasive deep-seated infections. For this purpose, 301 C. albicans isolates (81 invasive and 220 non-invasive) were genotyped by using specific PCR primers designed to span the transposable group I intron of the...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2004.01022.x
更新日期:2004-12-01 00:00:00
abstract::The serological responses to Cryptococcus neoformans proteins of blood donors and HIV patients with active cryptococcosis from a tropical region were investigated in this study. Exposure to C. neoformans, an organism ubiquitous in the environment, contributes to the antibody responses observed in the blood donors. IgG...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2008.01549.x
更新日期:2009-03-01 00:00:00
abstract::The aim of this study was to evaluate the effects of photodynamic therapy (PDT) using rose bengal or erythrosine with light emitting diode (LED) on Candida albicans planktonic cultures and biofilms. Seven C. albicans clinical strains and one standard strain (ATCC 18804) were used. Planktonic cultures and biofilms of e...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2011.02042.x
更新日期:2012-01-01 00:00:00
abstract::A review is presented of the emerging problem of resistant and chronic vaginitis due to Candida glabrata. Although accurate numbers are lacking, several investigators report encountering increased numbers of women with vaginitis due to C. glabrata. Possible reasons for this apparent increase are discussed. Risk factor...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.1998.tb00594.x
更新日期:1998-01-01 00:00:00
abstract::Comparative studies were performed to assess the stability and lot-to-lot variation of Blastomyces dermatitidis yeast and mycelial phase lysate antigens. Four lots were prepared from each growth phase of B. dermatitidis strain T-58 (canine isolate) during a 14-month period. Serum specimens from dogs with blastomycosis...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1994.tb00293.x
更新日期:1994-06-01 00:00:00
abstract::Tinea faciei is an uncommon dermatophytosis affecting the glabrous skin of the face. Between 1988 and 2007 at the Dermatology Department of Cagliari University, 107 cases of tinea faciei have been diagnosed, involving 72 females and 35 males, aged 2-72 years. Incidence peaks were observed between 6 and 15 years (48.59...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2009.01748.x
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:It was shown previously that dermatophytes can markedly be inhibited by a photochemical treatment with curcumin. This kind of photo-inactivation needs to be improved, however, because curcumin is poorly water-soluble. Therefore, a new water-soluble γ-cyclodextrin formulation of curcuminoids was tested for ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13051
更新日期:2020-04-01 00:00:00
abstract::Summary The authors report a case of bullous tinea pedis caused by Trichophyton violaceum with dermatophytid reaction in a 26-year-old woman who had been in Africa. Diagnosis was based on mycological examination (direct microscope observation and culture). Recovery was achieved after systemic antimycotic therapy with ...
journal_title:Mycoses
pub_type: 信件
doi:10.1111/j.1439-0507.2006.01234.x
更新日期:2006-05-01 00:00:00
abstract::Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was inves...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2010.01933.x
更新日期:2011-09-01 00:00:00
abstract::Eighteen adult white male patients with cutaneous sporotrichosis were treated with itraconazole following different daily dose schemes. Cure was obtained in all cases after periods of 15-75 days (median 44 days) with total doses between 3.1 and 14.8 g (median 8.4 g). No serious side effects were observed and no relaps...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1992.tb00836.x
更新日期:1992-05-01 00:00:00
abstract::The antifungal activities of extracts of 10 medicinal plants collected from south-eastern parts of Nigeria were tested against seven pathogenic fungi using the broth dilution and agar plate methods. All the extracts at 1:10 dilution inhibited the growth of Basidiobolus haptosporus and B. ranarum but did not inhibit th...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1995.tb00048.x
更新日期:1995-05-01 00:00:00
abstract::Onychomycosis was considered uncommon in children. This survey was carried out to estimate the frequency of fungal nail infections in children and adolescents (0-18 years of age) attending our clinic in the last decade and gain more insight into the aetiology and clinics of this entity in the paediatric age group. Thi...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2005.01186.x
更新日期:2006-01-01 00:00:00
abstract::A commercially available antigen assay (Pastorex Aspergillus) was used to detect Aspergillus antigen in serial bronchoalveolar lavage (BAL) fluids and sera of patients undergoing bone marrow transplantation (six patients with autopsyproven aspergillosis and 10 control patients without evidence of fungal infection). As...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1996.tb00155.x
更新日期:1996-09-01 00:00:00
abstract::Malassezia spp. form part of the normal human cutaneous flora and are implicated in several mild, but recurrent cutaneous diseases, such as pityriasis versicolor, Malassezia folliculitis, seborrhoeic dermatitis, and, with lesser frequency, a range of other dermatological disorders. Malassezia spp. have also been assoc...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.2009.01814.x
更新日期:2010-05-01 00:00:00
abstract::Studies of the genetic diversity of Candida albicans strains and the correlation between the antifungal susceptibility and gene diversity of C. albicans were carried out and the results were found to be inconsistent. To investigate antifungal susceptibility and genotypes of C. albicans strains from patients with vulvo...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2008.01539.x
更新日期:2009-01-01 00:00:00
abstract::New antifungal agents are needed to match the currently increasing rate of systemic fungal infections and the development of resistant fungal strains. This appears possible by the introduction of second generation azole antifungals which potently inhibit ergosterol synthesis, but also by a partial synthetic echinocand...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract::In Malassezia furfur, tryptophan as the main nitrogen source induces production of the potent ultraviolet-absorbing indole compound pityriacitrin. An in vitro study about the effects of pityriacitrin on other human skin microorganisms is presented, with special focus on Candida albicans and staphylococci in which its ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2006.01265.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Candida glabrata is the third leading cause of candidaemia in Turkey; however, the data regarding antifungal resistance mechanisms and genotypic diversity in association with their clinical implication are limited. OBJECTIVES:To assess genotypic diversity, antifungal susceptibility and mechanisms of drug re...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13104
更新日期:2020-09-01 00:00:00
abstract::It has always been difficult to treat onychomycosis due to decrease ability of topical agents to penetrate the nail and reach the affected nail bed. Oral antifungal have shown good response but due to longer duration course it has potential to cause systemic side effects, leading to patient non-adherence and adverse e...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/myc.12225
更新日期:2014-12-01 00:00:00
abstract::The authors report a case of subcutaneous mucormycosis in a diabetic patient with verrucous lesions in the fourth finger of the right hand. Initially diagnosed as a fixed cutaneous sporotrichosis case, success was obtained with the use of potassium iodide with healing of the lesion in a period of nearly 5 months. At p...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.1990.33.5.241
更新日期:1990-05-01 00:00:00
abstract::Cryptococcus gattii species complex has evolved as a pathogen in the last two decades causing infection among both immunocompetent and immunocompromised hosts. We aimed to analyse the clinical features of CNS infection caused by C. gattii sensu lato, molecular and antifungal susceptibility profile of this pathogen. Ca...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12656
更新日期:2017-11-01 00:00:00
abstract::We report a case of Aspergillus flavus pericarditis treated with fluconazole for oral candidosis. The patient with acute myeloblastic leukaemia developed tachypnoea after antileukaemic chemotherapy. Pericardial effusion was seen in the echocardiogram. Aspergillus flavus was isolated from the pericardial fluid. The pat...
journal_title:Mycoses
pub_type: 信件
doi:10.1046/j.1439-0507.2000.00540.x
更新日期:2000-01-01 00:00:00
abstract::Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis among immunocompetent patients in Latin America. This study aimed to describe the expansion over time and the geographical distribution of confirmed Neuroparacoccidioidomycosis (NPCM) and PCM cases, and relate it to environmental characteristics such ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12782
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:Candidaemia carries a mortality of up to 40% and may be related to increasing complexity of medical care. Here, we determined risk factors for the development of candidaemia. METHODS:We conducted a prospective, multi-centre, case-control study over 12 months. Cases were aged ≥18 years with at least one bloo...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13211
更新日期:2020-11-13 00:00:00
abstract::Airborne invasive fungal infections in various risk groups of people suffering from immunodeficiencies are an increasing problem for modern medicine. Because of the acute and rapid course of invasive infections, prevention is of principal significance. Such prevention mainly concerns the control of fungal spores in in...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.1992.tb00877.x
更新日期:1992-11-01 00:00:00
abstract::Onychomycosis in HIV-infected patients has a prevalence of 20-44% and is more frequently seen with CD4(+) T cell counts ≤450 cel μl(-1). There are case reports of improvement in onychomycosis after initiation of combined antiretroviral therapy (cART), but there are no prospective studies that prove the existence and f...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12350
更新日期:2015-09-01 00:00:00
abstract::This work presents the epidemiology of dermatomycoses and their etiological agents of people living in the Lódź region, Central Poland, over the years 1987-1996. The analysis involved subjects referred by physicians to three major mycological laboratories in Lódź (covering the entire mycological diagnostics of the Lód...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1046/j.1439-0507.1999.00454.x
更新日期:1999-01-01 00:00:00