Abstract:
:Oral, pharyngeal and esophageal infections caused by Candida species occur very frequently when it comes to radiation therapy for head and neck cancer. In clinical terms oral candidosis is most often characterized by pseudomembranes or erythema. The erythematous form of oral candidosis has in particular to be distinguished from radiation mucositis. Candidosis of the oral and gastrointestinal tract often causes interruption of therapeutic radiation. Ketoconazole treatment is able to reduce the period of time during which the patient cannot be treated by radiation. Oral ketoconazole given at a daily dose of 200 mg is moreover superior to topical nystatin. To date, however, it is not yet clear if patients who have head and neck cancer in whom radiation therapy has to be started would profit from the prophylactic application of ketoconazole from start on.
journal_name
Mycosesjournal_title
Mycosesauthors
Poland JMdoi
10.1111/j.1439-0507.1989.tb02308.xsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
39-41eissn
0933-7407issn
1439-0507journal_volume
32 Suppl 2pub_type
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