Histopathologic and histochemical characterization of calcified structures in hamsters inoculated with Paracoccidioides brasiliensis.

Abstract:

:In pathogenicity studies of 31 Paracoccidioides brasiliensis isolates preserved using Castellani's method we intraperitoneally inoculated 104 young adult hamsters and found laminated concentric structures and calcified appearance that resembled Schaumann bodies, in 43 of them, especially in animals with apparently good condition. We characterized these structures histologically and histochemically using different stains (PAS, Grocott, haematoxylin-eosin, Von Kossa). The Von Kossa staining revealed calcium in these structures. Similar structures have been described in patients with sarcoidosis and also in hamsters inoculated with P. brasiliensis. We found no correlation between the presence of these calcifications and serum calcium levels.

journal_name

Mycoses

journal_title

Mycoses

authors

Essayag SM,Landaeta ME,Hartung C,Magaldi S,Spencer L,Suárez R,García F,Pérez E

doi

10.1046/j.1439-0507.2002.00785.x

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

351-7

issue

9-10

eissn

0933-7407

issn

1439-0507

pii

785

journal_volume

45

pub_type

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