Multicentric genetic study of Candida albicans isolates from non-neutropenic patients using MLEE typing: population structure and mode of reproduction.

Abstract:

:A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus enzyme electrophoresis (MLEE). The enzyme profiles obtained from 15 polymorphic loci were then compared. This analysis demonstrated a strong population differentiation of C. albicans infective strains within and between the different care units and confirmed the probable preponderant clonal mode of reproduction of this yeast.

journal_name

Mycoses

journal_title

Mycoses

authors

Arnavielhe S,De Meeüs T,Blancard A,Mallié M,Renaud F,Bastide JM

doi

10.1046/j.1439-0507.2000.00552.x

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

109-17

issue

3-4

eissn

0933-7407

issn

1439-0507

journal_volume

43

pub_type

杂志文章,多中心研究

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