abstract：BACKGROUND:Patients undergoing allogeneic stem cell transplantation (aSCT) are at high risk to develop an invasive fungal disease (IFD). Optimisation of antifungal prophylaxis strategies may improve patient outcomes and reduce treatment costs. OBJECTIVES:To analyse the clinical and economical impact of using continuou...

journal_title：Mycoses

authors： Wingen-Heimann SM,Cornely OA,J G T Vehreschild M,Wisplinghoff H,Franke B,Schons M,von Bergwelt-Baildon M,Scheid C,Vehreschild JJ

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:Sporotrichosis is a subcutaneous mycosis caused by Sporothrix species that affects humans and animals. Little information on the genetic diversity and population structure of the pathogen is available for Brazil, which is needed to design effective strategies to tackle the advance of sporotrichosis in endemi...

journal_title：Mycoses

authors： da Cruz Bahiense Rocha I,Terra PPD,Cardoso de Oliveira R,Lubianca Zanotti R,Falqueto A,de Camargo ZP,Rodrigues AM,Gonçalves SS

更新日期：2020-12-18 00:00:00

abstract：OBJECTIVES:Candidaemia carries a mortality of up to 40% and may be related to increasing complexity of medical care. Here, we determined risk factors for the development of candidaemia. METHODS:We conducted a prospective, multi-centre, case-control study over 12 months. Cases were aged ≥18 years with at least one bloo...

journal_title：Mycoses

authors： Keighley CL,Pope A,Marriott DJE,Chapman B,Bak N,Daveson K,Hajkowicz K,Halliday C,Kennedy K,Kidd S,Sorrell TC,Underwood N,van Hal S,Slavin MA,Chen SC

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Light microscopy to study the infection of fungi in skin specimens is time-consuming and requires automation. OBJECTIVE:We aimed to design and explore the application of an automated microscope for fungal detection in skin specimens. METHODS:An automated microscope was designed, and a deep learning model w...

journal_title：Mycoses

authors： Gao W,Li M,Wu R,Du W,Zhang S,Yin S,Chen Z,Huang H

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Acute myeloid leukaemia (AML) patients are at high risk of invasive aspergillosis (IA) after first induction chemotherapy (CHT). Although IA risk factors have been identified, few data are available on impact of IA, occurring during induction phase, on overall AML outcome. PATIENTS AND RESULTS:The end point...

journal_title：Mycoses

authors： Candoni A,Farina F,Perruccio K,Di Blasi R,Criscuolo M,Cattaneo C,Delia M,Zannier ME,Dragonetti G,Fanci R,Martino B,Del Principe MI,Fianchi L,Vianelli N,Chierichini A,Garzia M,Petruzzellis G,Nadali G,Verga L,Busca A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Candida glabrata is the third leading cause of candidaemia in Turkey; however, the data regarding antifungal resistance mechanisms and genotypic diversity in association with their clinical implication are limited. OBJECTIVES:To assess genotypic diversity, antifungal susceptibility and mechanisms of drug re...

journal_title：Mycoses

authors： Arastehfar A,Daneshnia F,Salehi M,Yaşar M,Hoşbul T,Ilkit M,Pan W,Hagen F,Arslan N,Türk-Dağı H,Hilmioğlu-Polat S,Perlin DS,Lass-Flörl C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Candidaemia in the elderly has not been extensively investigated. OBJECTIVES:We compared the management of candidaemia in the elderly patients (age ≥65 years) and the very elderly subgroup of patients (age ≥75 years) with those belonging to the younger group (age <65 years) using the European Confederation ...

journal_title：Mycoses

authors： Bal AM,Palchaudhuri M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Invasive pulmonary aspergillosis (IPA) is a complication of respiratory bacterial and viral infections such as coronavirus disease 2019 (COVID-19). PATIENTS/METHODS:In University Hospital La Paz (Madrid, Spain), we reviewed the clinical and demographic characteristics of 10 patients with positive severe acu...

journal_title：Mycoses

authors： Falces-Romero I,Ruiz-Bastián M,Díaz-Pollán B,Maseda E,García-Rodríguez J,SARS-CoV-2 Working Group.

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Invasive fungal disease is a major cause of morbidity and mortality in children with cancer and high-risk febrile neutropenia (HRFN). Repeated serum galactomannan (sGM) measurements have been described as an effective tool to guide therapy in adults under suspicion of invasive aspergillosis. However, the uti...

journal_title：Mycoses

authors： Delgado-Araneda M,Valenzuela R,de la Maza V,Rabello M,Álvarez AM,Contardo V,Zubieta M,Gutierrez V,Claverie X,Torres JP,Salgado C,Tordecilla J,Varas M,Avilés CL,Venegas M,Villarroel M,Santolaya ME

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Invasive mould infections (IMIs) are very rare in patients with lymphoid malignancies. However, IMIs, mostly due to Aspergillus species, have been increasingly reported in such patients receiving ibrutinib (IBR). There is paucity of information regarding non-Aspergillus invasive mould infections (NAIMIs) in ...

journal_title：Mycoses

authors： Anastasopoulou A,DiPippo AJ,Kontoyiannis DP

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:We aimed to implement and to assess the impact of the antifungal stewardship programme (AFSp) on prescription appropriateness of antifungals, management and outcomes of candidaemia patients, and antifungal consumption and costs at our solid organ transplant (SOT) institute. METHODS:Local epidemiology of invasi...

journal_title：Mycoses

authors： Mularoni A,Adamoli L,Polidori P,Ragonese B,Gioè SM,Pietrosi A,Tuzzolino F,Guadagnino G,Monaco F,Grossi PA,Conaldi PG,Luca A,Mikulska M

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany. METHODS:A retrospective chart r...

journal_title：Mycoses

authors： Koehler P,Cornely OA,Böttiger BW,Dusse F,Eichenauer DA,Fuchs F,Hallek M,Jung N,Klein F,Persigehl T,Rybniker J,Kochanek M,Böll B,Shimabukuro-Vornhagen A

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:It was shown previously that dermatophytes can markedly be inhibited by a photochemical treatment with curcumin. This kind of photo-inactivation needs to be improved, however, because curcumin is poorly water-soluble. Therefore, a new water-soluble γ-cyclodextrin formulation of curcuminoids was tested for ...

journal_title：Mycoses

authors： Brasch J,Beck-Jendroschek V,Walther G,Rubbel D

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Mycetoma is a pathological process in which fungal or actinomycotic agents of exogenous origin produce grains. In the absence of data on the global burden, it is important to map mycetoma cases, which are useful to implement control strategies. OBJECTIVE:The objective of this study was to map mycetoma cases...

journal_title：Mycoses

authors： Badiane AS,Ndiaye M,Diongue K,Diallo MA,Seck MC,Ndiaye D

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Oral follow-up therapy is problematic in moulds with reduced azole-susceptibility, such as azole-resistant Aspergillus fumigatus infection. Currently, only intravenous liposomal amphotericin B (L-AmB) is advocated by guidelines for the treatment of azole-resistant aspergillosis infections. Preclinical resear...

journal_title：Mycoses

authors： Schauwvlieghe AFAD,Buil JB,Verweij PE,Hoek RAS,Cornelissen JJ,Blijlevens NMA,Henriet SSV,Rijnders BJA,Brüggemann RJM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic value of serum Candida mannan antigen (MN) and anti-mannan IgG and IgM antibodies for candidiasis. METHODS:This study was a prospective cohort study. Clinical data and venous blood samples from 23 medical centres in Beijing, China were collected between 1 January 2017 and 31 December...

journal_title：Mycoses

authors： Wang K,Luo Y,Zhang W,Xie S,Yan P,Liu Y,Li Y,Ma X,Xiao K,Fu H,Cai J,Xie L

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The infections caused by fungi represent a global concern and an important cause of hospital admissions in endemic areas. The influence of socio-environmental factors in infectious diseases has been documented; however, this phenomenon remains unclear regarding mycoses. OBJECTIVES:This study aimed to analys...

journal_title：Mycoses

authors： da Silva LC,de Oliveira LVN,Silva FB,Santos JRN,de Araújo MLS,Mendes AGG,Miranda RCM,Santos DA,Holanda RA,Santos JRA

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Cryptococcal meningitis accounts for 15% of all AIDS mortality globally. Most cases in low- and middle-income countries are treated with fluconazole monotherapy, which is associated with a high mortality. New available therapies are needed. Short-course amphotericin B has been shown to be a safe and efficien...

journal_title：Mycoses

authors： Katende A,Mbwanji G,Faini D,Nyuri A,Kalinjuma AV,Mnzava D,Hullsiek KH,Rhein J,Weisser M,Meya DB,Boulware DR,Letang E,KIULARCO Study Group.

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Microsporum canis is a zoophilic species, found to be the most frequently isolated species in animals. M. canis causes sporadic outbreaks of infections in humans, such as the one that occurred in Canada, where more than 1000 human cases were detected over an 8-year period. Despite the medical importance of M...

journal_title：Mycoses

authors： Abastabar M,Jedi A,Guillot J,Ilkit M,Eidi S,Hedayati MT,Shokohi T,Daie Ghazvini R,Rezaei-Matehkolaei A,Katiraee F,Javidnia J,Ahmadi B,Badali H

更新日期：2019-11-01 00:00:00

abstract：:Cryptococcal meningitis (CM) is one of the most common opportunistic infections of acquired immunodeficiency syndrome (AIDS), as well as an important cause of hospitalisation and death. In recent years, the mortality of CM has remained high in HIV/AIDS population, with up to 30%, including within developed countries. ...

journal_title：Mycoses

authors： Wu X,Shen Y

更新日期：2019-10-01 00:00:00

abstract：:Outbreaks of tinea capitis (TC) can be a source of medical and economic burden for healthcare systems; Griseofulvin and terbinafine are considered to be effective first-line treatments for TC. In order to compare the efficacy of griseofulvin and terbinafine for the treatment of TC in a paediatric population of African...

journal_title：Mycoses

authors： Bar J,Samuelov L,Sprecher E,Mashiah J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Pulmonary cryptococcosis (PC) is not considered an rare, opportunistic infection anymore. The immunocompetent population accounts for an increasing proportion of the morbidity. OBJECTIVE:This study investigated the clinical characteristics of PC patients spanning 20 years, in a referral centre of China. PA...

journal_title：Mycoses

authors： Hou X,Kou L,Han X,Zhu R,Song L,Liu T

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Loop-mediated isothermal amplification (LAMP) assays, which operate at a single temperature and require no postreaction processing, have been described for rapid species-specific detection of numerous fungi. The technology has much less commonly been applied to identification of other key genetic traits such...

journal_title：Mycoses

authors： King KM,Hawkins NJ,Atkins S,Dyer PS,West JS,Fraaije BA

更新日期：2019-09-01 00:00:00

abstract：:Mucormycosis mostly affects immunocompromised patients and is associated with a high morbidity and mortality despite currently available treatments. In that context, combination therapy might be the key to a better outcome for these patients. Purpose of this review is to summarise and to discuss the current combinatio...

journal_title：Mycoses

authors： Schwarz P,Cornely OA,Dannaoui E

更新日期：2019-09-01 00:00:00

abstract：:Breakthrough invasive fungal infections (IFIs) have emerged as a significant problem in patients receiving systemic antifungals; however, consensus criteria for defining breakthrough IFI are missing. This position paper establishes broadly applicable definitions of breakthrough IFI for clinical research. Representativ...

journal_title：Mycoses

authors： Cornely OA,Hoenigl M,Lass-Flörl C,Chen SC,Kontoyiannis DP,Morrissey CO,Thompson GR 3rd,Mycoses Study Group Education and Research Consortium (MSG-ERC) and the European Confederation of Medical Mycology (ECMM).

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Cryptococcal meningitis has fatality rates of 40%-70%, resulting in 200 000 deaths each year. The best outcomes are achieved with amphotericin combined with flucytosine but flucytosine is expensive and unavailable where most disease occurs. More effective and affordable treatments are needed. Tamoxifen, a se...

journal_title：Mycoses

authors： Hai TP,Van AD,Ngan NTT,Nhat LTH,Lan NPH,Vinh Chau NV,Thwaites GE,Krysan D,Day JN

更新日期：2019-09-01 00:00:00

abstract：:Posaconazole is indicated for prophylaxis and treatment of invasive aspergillosis. Therapeutic drug monitoring (TDM) of posaconazole is used to optimise drug exposure. The aim of this study was to analyse and describe the TDM practices and exposure of posaconazole tablets. Patients who received posaconazole for treatm...

journal_title：Mycoses

authors： Märtson AG,Veringa A,van den Heuvel ER,Bakker M,Touw DJ,van der Werf TS,Span LFR,Alffenaar JC

更新日期：2019-08-01 00:00:00

abstract：:The prevalence of atopic dermatitis (AD) has been increasing. Whereas AD symptoms are obvious and easy to recognise, the etiopathogenesis remains not fully elucidated. Recently, the role of microorganisms and their impact on the immunology of AD have been discussed. In this review, we summarise a possible role of Mala...

journal_title：Mycoses

authors： Nowicka D,Nawrot U

更新日期：2019-07-01 00:00:00

abstract：:Although case series of talaromycosis have been reported in China, their detailed clinical and microbiological characteristics have never been systematically profiled. In this study, we report the clinical characteristics, molecular epidemiology, rapid identification and antifungal susceptibilities of talaromycosis in...

journal_title：Mycoses

authors： Lau SKP,Xing F,Tsang CC,Tang JYM,Tan YP,Ye H,Lau RWT,Chen JHK,Lo SKF,Woo PCY

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Clioquinol was used in the 1950s-1970s as antimicrobial but its oral formulations were withdrawn from the market due to suspected neurotoxicity. Currently, there is possibility of repositioning of oral clioquinol formulations. OBJECTIVES:To evaluate the antifungal activity and toxicological parameters of cl...

journal_title：Mycoses

authors： Pippi B,Merkel S,Staudt KJ,Teixeira ML,de Araújo BV,Zanette RA,Andrade SF,Fuentefria AM

更新日期：2019-05-01 00:00:00

abstract：:Despite the existence of endemic mycoses in Latin America and the Caribbean, in addition to a large population of patients at risk for invasive mycoses, the capability of medical centres to perform a proper diagnosis in mycology has not been studied in the region. Moreover, availability of antifungal drugs in the regi...

journal_title：Mycoses

authors： Falci DR,Pasqualotto AC

更新日期：2019-04-01 00:00:00

abstract：:Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring. Many patients with fungal infections require prolonged therapy due to resistance ...

journal_title：Mycoses

authors： Rae N,Kenny C,Muldoon EG

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Histoplasmosis is a frequent fungal infection in HIV/AIDS patients, with high morbimortality rates when diagnosis and treatment are delayed. Antibody detection, which is faster than the gold standard culture test, hastens the laboratory investigation. OBJECTIVES:To evaluate the role of WB for antibody detec...

journal_title：Mycoses

authors： Almeida MA,Damasceno LS,Pizzini CV,Muniz MM,Almeida-Paes R,Zancopé-Oliveira RM

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The incidence of fungal keratitis has increased in recent years. While the epidemiology and clinical roles of various Candida and Fusarium species have been relatively well-identified in infections of the eye, data regarding keratitis caused by Aspergillus species are scant. Accurate and rapid diagnosis is i...

journal_title：Mycoses

authors： Al-Hatmi AMS,Castro MA,de Hoog GS,Badali H,Alvarado VF,Verweij PE,Meis JF,Zago VV

更新日期：2019-02-01 00:00:00

abstract：:We present four cases of interdigital tinea pedis in Italian tourists which was probably acquired in Turkish mosques and holy Muslim places. In all patients mycological examinations were positive for Trichophyton rubrum. All patients were successfully treated with bifonazole cream (one application/day for three weeks)...

journal_title：Mycoses

authors： Veraldi S,Esposito L,Gorani A

更新日期：2018-11-01 00:00:00

abstract：:Invasive pulmonary aspergillosis is a serious threat to immunocompromised and critical care patients. Recent detailed guidelines and treatment algorithms lead microbiologists and clinicians in diagnosis and treatment of invasive aspergillosis. Currently, there is no tool available that allows to measure guideline adhe...

journal_title：Mycoses

authors： Cornely OA,Koehler P,Arenz D,C Mellinghoff S

更新日期：2018-11-01 00:00:00

abstract：:Amphotericin formulations, indicated for invasive fungal infections (IFIs), vary in effectiveness, safety and costs. In Brazil, only the conventional formulation is provided by the Public Health System. The aim of this study was to perform a cost-effectiveness analysis comparing conventional amphotericin B (CAB), lipo...

journal_title：Mycoses

authors： Borba HHL,Steimbach LM,Riveros BS,Tonin FS,Ferreira VL,Bagatim BAQ,Balan G,Pontarolo R,Wiens A

更新日期：2018-10-01 00:00:00

abstract：:Exophiala is a genus of black fungi isolated worldwide from environmental and clinical specimens. Data on antifungal susceptibility of Exophiala isolates are limited and the methodology on susceptibility testing is not yet standardised. In this study, we investigated in vitro antifungal susceptibilities of environment...

journal_title：Mycoses

authors： Gülmez D,Doğan Ö,Boral B,Döğen A,İlkit M,de Hoog GS,Arikan-Akdagli S

更新日期：2018-08-01 00:00:00

abstract：:Detection of serum galactomannan (GM) and (1,3)-β-d-glucan (BG) is considered useful for non-culture diagnosis of invasive pulmonary aspergillosis (IPA) in neutropenic patients. Only few studies evaluated these seromarkers in non-neutropenic patients suspected of having IPA. The aim of this study was to evaluate both ...

journal_title：Mycoses

authors： Dobias R,Jaworska P,Tomaskova H,Kanova M,Lyskova P,Vrba Z,Holub C,Svobodová L,Hamal P,Raska M

更新日期：2018-08-01 00:00:00

abstract：:Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis among immunocompetent patients in Latin America. This study aimed to describe the expansion over time and the geographical distribution of confirmed Neuroparacoccidioidomycosis (NPCM) and PCM cases, and relate it to environmental characteristics such ...

journal_title：Mycoses

authors： de Almeida SM,Salvador GLO,Roza TH,Izycki LF,Dos Santos I,Aragão A,Kulik A,Muro M,Torres LFB,de Noronha L

更新日期：2018-08-01 00:00:00