Abstract:
:Fifty strains of Candida isolated from 38 patients with oropharyngeal candidosis were tested in vitro for fluconazole susceptibility with a disk diffusion test and for determination of minimal inhibitory concentrations (MICs). For 25 patients treated with fluconazole, the relationship between in vitro susceptibility and clinical outcome was analysed. A good correlation between in vitro results and therapeutic efficacy was found. In only one case was treatment failure associated with a susceptible strain. Mixed cultures of Candida albicans and non-albicans Candida species were not uncommon and, more interestingly, some samples contained different strains of C. albicans with varied fluconazole susceptibilities. Good agreement was observed between the two techniques used for fluconazole susceptibility testing.
journal_name
Mycosesjournal_title
Mycosesauthors
Dannaoui E,Lacoste V,Prat C,Piens MAdoi
10.1111/j.1439-0507.1997.tb00232.xsubject
Has Abstractpub_date
1997-11-01 00:00:00pages
279-82issue
7-8eissn
0933-7407issn
1439-0507journal_volume
40pub_type
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