Fluconazole susceptibility of Candida isolates from oropharyngeal candidosis.

Abstract:

:Fifty strains of Candida isolated from 38 patients with oropharyngeal candidosis were tested in vitro for fluconazole susceptibility with a disk diffusion test and for determination of minimal inhibitory concentrations (MICs). For 25 patients treated with fluconazole, the relationship between in vitro susceptibility and clinical outcome was analysed. A good correlation between in vitro results and therapeutic efficacy was found. In only one case was treatment failure associated with a susceptible strain. Mixed cultures of Candida albicans and non-albicans Candida species were not uncommon and, more interestingly, some samples contained different strains of C. albicans with varied fluconazole susceptibilities. Good agreement was observed between the two techniques used for fluconazole susceptibility testing.

journal_name

Mycoses

journal_title

Mycoses

authors

Dannaoui E,Lacoste V,Prat C,Piens MA

doi

10.1111/j.1439-0507.1997.tb00232.x

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

279-82

issue

7-8

eissn

0933-7407

issn

1439-0507

journal_volume

40

pub_type

杂志文章

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