High-dose posaconazole for azole-resistant aspergillosis and other difficult-to-treat mould infections.

abstract：:Cerebral aspergillosis usually occurs in severely immunocompromized hosts, is difficult to diagnose, and has a poor prognosis. After 14 months of chronic meningitis, ventriculitis, choroid plexitis, and lumbar arachnoiditis, which was complicated by acute hydrocephalus, Aspergillus, suspected to be from the candidus g...

journal_title：Mycoses

authors： Moling O,Lass-Floerl C,Verweij PE,Porte M,Boiron P,Prugger M,Gebert U,Corradini R,Vedovelli C,Rimenti G,Mian P

更新日期：2002-12-01 00:00:00

abstract：:The effect of three azole antifungals on inducible nitric oxide (iNOS) activity in different mouse and human cells was evaluated. The iNOS activity was determined by L-citrulline and nitrite measurement. In the murine macrophage cell line RAW 264.7, in mouse peritoneal macrophages (MPM) and in human colorectal adenoca...

journal_title：Mycoses

authors： Vermuyten K,Laurijssens L,Vanden Bossche H

更新日期：1997-09-01 00:00:00

abstract：:Comparative studies were performed to assess the stability and lot-to-lot variation of Blastomyces dermatitidis yeast and mycelial phase lysate antigens. Four lots were prepared from each growth phase of B. dermatitidis strain T-58 (canine isolate) during a 14-month period. Serum specimens from dogs with blastomycosis...

journal_title：Mycoses

authors： Orr ML,Bono JL,Abuodeh RO,Williams SJ,Legendre AM,Scalarone GM

更新日期：1994-06-01 00:00:00

abstract：:Invasive pulmonary aspergillosis is a serious threat to immunocompromised and critical care patients. Recent detailed guidelines and treatment algorithms lead microbiologists and clinicians in diagnosis and treatment of invasive aspergillosis. Currently, there is no tool available that allows to measure guideline adhe...

journal_title：Mycoses

authors： Cornely OA,Koehler P,Arenz D,C Mellinghoff S

更新日期：2018-11-01 00:00:00

abstract：:Due to the Fourier-Transform Infrared Spectroscopy (FT-IR) of strain specific traits demonstrated to be a suitable and efficient method for diagnostic and epidemiological determinations for the yeasts Candida albicans, Exophiala dermatitidis and the chlorophylless algae of the genus Prototheca. FT-IR leads in a rapid ...

journal_title：Mycoses

authors： Schmalreck AF,Tränkle P,Vanca E,Blaschke-Hellmessen R

更新日期：1998-01-01 00:00:00

abstract：:The MIC values of the antifungal drug ketoconazole were evaluated on 66 Candida albicans strains. These strains were isolated from 26 HIV-1 infected patients with oral recurrent candidosis. Each episode of oral candidosis observed in these patients was orally treated with ketoconazole (200 mg/day) until the clinical d...

journal_title：Mycoses

authors： Bruatto M,Marinuzzi G,Raiteri R,Sinicco A

更新日期：1992-01-01 00:00:00

abstract：:A universal PCR-assay for the detection of fungal DNA was compared with microscopy and culture for the diagnosis of invasive aspergillosis using 78 samples from 42 patients. Eighteen patients were suffering from invasive aspergillosis, 5 patients were colonized with Aspergillus in the respiratory tract, 19 patients di...

journal_title：Mycoses

authors： Rimek D,Garg AP,Kappe R,Sonntag HG

更新日期：1998-01-01 00:00:00

abstract：:Pityriasis versicolor (p.v.) is a superficial mycosis occurring frequently on the face. Epidemiological and clinical data regarding cases of p.v. on the face over a period of 11 years are discussed and some explanation given for conditions which favour facial involvement. This study underlines that face lesions of p.v...

journal_title：Mycoses

authors： Terragni L,Lasagni A,Oriani A

更新日期：1991-07-01 00:00:00

abstract：:Bone lesions in African histoplasmosis caused by Histoplasma capsulatum var, duboisii, without other signs of the infection, are often misdiagnosed as cancer. A case of isolated osteomyelitis due to this fungus in a 30-year-old woman is described. Diagnostic and therapeutic problems of isolated bone lesions in African...

journal_title：Mycoses

authors： Onwuasoigwe O,Gugnani HC

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Cryptococcal meningitis has fatality rates of 40%-70%, resulting in 200 000 deaths each year. The best outcomes are achieved with amphotericin combined with flucytosine but flucytosine is expensive and unavailable where most disease occurs. More effective and affordable treatments are needed. Tamoxifen, a se...

journal_title：Mycoses

authors： Hai TP,Van AD,Ngan NTT,Nhat LTH,Lan NPH,Vinh Chau NV,Thwaites GE,Krysan D,Day JN

更新日期：2019-09-01 00:00:00

abstract：:For several years, the Platelia Candida mannan antigen enzyme immunoassay (Candida EIA) has been commercially available as a diagnostic test for invasive candidosis. We evaluated the Candida EIA with patients with proven fungemia caused by yeasts from which at least one serum sample was available. Fifty-nine patients ...

journal_title：Mycoses

authors： Rimek D,Redetzke K,Singh J,Heinrich K,Kappe R

更新日期：2004-01-01 00:00:00

abstract：:Cunninghamella bertholletiae, a rare causative agent of mycosis among immunocompromised patients has been reported with increased frequency from western countries in recent years. We report a case of C. bertholletiae pulmonary infection in a 42-year-old male patient who developed graft-vs.-host disease following bone ...

journal_title：Mycoses

authors： Sivakumar S,Mathews MS,George B

更新日期：2005-09-01 00:00:00

abstract：:A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus ...

journal_title：Mycoses

authors： Arnavielhe S,De Meeüs T,Blancard A,Mallié M,Renaud F,Bastide JM

更新日期：2000-01-01 00:00:00

abstract：:This is an observational-retrospective study comparing the real-world outcomes associated with posaconazole vs itraconazole as prophylaxis treatments. Two hundred and ninety-three patient admissions attributable to 174 patients were included in the study. Patients were treated with itraconazole (n = 114 admissions; 39...

journal_title：Mycoses

authors： Tormo M,Pérez-Martínez A,Calabuig M,Hernández-Boluda JC,Amat P,Navarro D,Solano C

更新日期：2018-03-01 00:00:00

abstract：:The patient we present herein is a 6-month-old infant who had erythema and scaling on the central part of the face for 4 months. Both the abundant scaling and the localisation, but also the low age of this infant led to suspect seborrhoeic dermatitis. Direct microscopic examination of scales showed septate hyphae and ...

journal_title：Mycoses

authors： Polat M,Artüz F,Karaaslan A,Oztaş P,Lenk N,Alli N

更新日期：2007-11-01 00:00:00

abstract：:Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was inves...

journal_title：Mycoses

authors： Raggam RB,Salzer HJ,Marth E,Heiling B,Paulitsch AH,Buzina W

更新日期：2011-09-01 00:00:00

abstract：:An atypical strain of Paracoccidioides brasiliensis was obtained from a patient with disseminated paracoccidioidomycosis. This isolate, which has been maintained in the laboratory for 4 years by successive subcultures (30-40 days) in Fava Netto medium, produces cerebriform colonies characteristic of the yeast phase of...

journal_title：Mycoses

authors： Hamdan JS,Ferrari TC

更新日期：1995-11-01 00:00:00

abstract：:We report on a 65-year-old diabetic patient, who developed a deep fungal infection in the beard region after initial therapy with systemic antibiotics and topical corticosteroids. We were able to isolate Trichophyton mentagrophytes and treated him successfully with terbinafine 250 mg day(-1) orally in combination with...

journal_title：Mycoses

authors： Hohaus K,Vennewald I,Wollina U

更新日期：2003-09-01 00:00:00

abstract：:The first case of a cutaneous cryptococcosis associated with systemic erythematous lupus (SLE) diagnosed in our Mycology Reference Centre is presented: a 24-year-old female patient diagnosed with SLE, nephrotic syndrome, arterial hypertension, renal insufficiency due to glomerulonephritis type IV and cellulitis in the...

journal_title：Mycoses

authors： Ramos L,López C,Gómez C,Mathurín S,Mateo A

更新日期：2001-11-01 00:00:00

abstract：:Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised and critically ill patients. Standard culture based methods for the diagnosis of Aspergillus infections have limited sensitivity and specificity and are time consuming. The recent availability of novel molecular based diagnostic te...

journal_title：Mycoses

authors： Faber J,Moritz N,Henninger N,Zepp F,Knuf M

更新日期：2009-05-01 00:00:00

abstract：:An early diagnosis of an invasive fungal infection is essential for the initiation of a specific antifungal therapy and to avoid unnecessary discontinuation of a baseline therapy for haematological or oncological diseases. A real-time PCR assay for the detection and strain identification of Aspergillus species from cu...

journal_title：Mycoses

authors： Fricke S,Fricke C,Oelkrug C,Blatz R,Schönfelder U,Niederwieser D,Hilger N,Ruhnke M,Rodloff AC

更新日期：2012-09-01 00:00:00

abstract：:Infections caused by yeast of the genus Candida are the most common fungal infections, being Candida albicans the most common isolated species among them. The rapid identification of this yeast is mostly based on the production of germ tube in human or animal serum. This study describes the use of 12 different liquid ...

journal_title：Mycoses

authors： Hilmioglu S,Ilkit M,Badak Z

更新日期：2007-07-01 00:00:00

abstract：:For anthropophilic tinea capitis (TC), household spread and asymptomatic scalp carriage (ASC) is considered an important route of transmission and incomplete clearance. To investigate ASC in household contacts of patients diagnosed with TC in a tertiary hospital in Athens, Greece, we retrospectively reviewed the medic...

journal_title：Mycoses

authors： Dessinioti C,Papadogeorgaki E,Athanasopoulou V,Antoniou C,Stratigos AJ

更新日期：2014-06-01 00:00:00

abstract：:One hundred and fifty cases of corneal ulcers from the Government Ophthalmic Hospital, Madras, were investigated during 1980-1982 for the mycoflora. 68 cases (45%) were positive for fungi, comprising species of Aspergillus (36 cases), Penicillium, Fusarium (8 cases each), Curvularia (4 cases), Candida albicans and Muc...

journal_title：Mycoses

authors： Sundaram BM,Badrinath S,Subramanian S

更新日期：1989-11-01 00:00:00

abstract：:An in vitro microassay for the measurement of Candida albicans hyphal-form growth inhibition by myelomonocytic cells is described. The assay is rapid, easy-to-perform and objective. A Candida strain capable of in vitro dimorphic transition from yeast to hyphal form has been employed. The assay is based on the incorpor...

journal_title：Mycoses

authors： Scaringi L,Blasi E,Cornacchione P,Bietta C,Bistoni F

更新日期：1991-03-01 00:00:00

abstract：:Scedosporium apiospermum is an emerging agent of opportunistic mycoses in humans. Previously, we showed that mycelia of S. apiospermum secreted metallopeptidases which were directly linked to the destruction of key host proteins. In this study, we analysed the effect of metallopeptidase inhibitors on S. apiospermum de...

journal_title：Mycoses

authors： Silva BA,Souza-Gonçalves AL,Pinto MR,Barreto-Bergter E,Santos AL

更新日期：2011-03-01 00:00:00

abstract：:The aim of this study was to investigate a possible effect of optical brighteners on the growth of dermatophytes. Typical strains of Trichophyton rubrum, T. mentagrophytes, Microsporum canis and Epidermophyton floccosum were grown on agar plates containing two different brighteners of stilbenedisulfonic acid type in c...

journal_title：Mycoses

authors： Brasch J,Kreiselmaier I,Christophers E

更新日期：2003-04-01 00:00:00

abstract：:Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis among immunocompetent patients in Latin America. This study aimed to describe the expansion over time and the geographical distribution of confirmed Neuroparacoccidioidomycosis (NPCM) and PCM cases, and relate it to environmental characteristics such ...

journal_title：Mycoses

authors： de Almeida SM,Salvador GLO,Roza TH,Izycki LF,Dos Santos I,Aragão A,Kulik A,Muro M,Torres LFB,de Noronha L

更新日期：2018-08-01 00:00:00

abstract：:Onychomycosis was considered uncommon in children. This survey was carried out to estimate the frequency of fungal nail infections in children and adolescents (0-18 years of age) attending our clinic in the last decade and gain more insight into the aetiology and clinics of this entity in the paediatric age group. Thi...

journal_title：Mycoses

authors： Lange M,Roszkiewicz J,Szczerkowska-Dobosz A,Jasiel-Walikowska E,Bykowska B

更新日期：2006-01-01 00:00:00

abstract：:Mucormycosis, previously termed as zygomycosis, is caused by fungi belonging to the order Mucorales and is a very severe disease in immunocompromised patients with an often unfavourable outcome. Given the high morbidity and mortality of mucormycosis, establishing a timely diagnosis followed by immediate treatment is o...

journal_title：Mycoses

authors： Tacke D,Koehler P,Markiefka B,Cornely OA

更新日期：2014-09-01 00:00:00