Eosinophilic fungal rhinosinusitis due to the unusual pathogen Curvularia inaequalis.

Abstract:

:Among fungi, Curvularia inaequalis is a rare pathogen. We report the first case of non-invasive fungal rhinosinusitis caused by this species. Endoscopic sinus surgery revealed massive polyposis and the presence of viscous eosinophilic mucus that allowed the growth of the fungus. We diagnosed eosinophilic fungal rhinosinusitis based on the histological findings of fungal hyphae in association with degranulating eosinophils in the sinus mucus. After polypectomy and clearance of the affected sinuses, oral itraconazole was administered to prevent the recurrence. Given the ever-increasing list of opportunistic fungi that cause human infection, the case reported here provides further evidence that proper identification of the infective agents remains crucial for the patient's management.

journal_name

Mycoses

journal_title

Mycoses

authors

Posteraro B,Scarano E,La Sorda M,Torelli R,De Corso E,Mulé A,Paludetti G,Fadda G,Sanguinetti M

doi

10.1111/j.1439-0507.2008.01671.x

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

84-8

issue

1

eissn

0933-7407

issn

1439-0507

pii

MYC1671

journal_volume

53

pub_type

信件

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