Aquaporin-2 as a biomarker of distal renal tubular function using lithium as an experimental model.

Abstract:

:Aquaporin-2 protein levels can be detected in the urine of normal of subjects if measured after fluid deprivation. By contrast, in patients with nephrogenic diabetes insipidus caused by mutations in the aquaporin-2 gene, urine aquaporin-2 protein excretion cannot be detected. We propose that properly standardized measurements of urinary aquaporin-2 protein may provide a useful biomarker of distal tubular function in a variety of acquired conditions that impair concentrating ability including some nephrotoxic agents.

journal_name

Ren Fail

journal_title

Renal failure

authors

Sisson D,Batlle D

doi

10.3109/08860229909085095

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

331-6

issue

3-4

eissn

0886-022X

issn

1525-6049

journal_volume

21

pub_type

杂志文章,评审
  • Spontaneous perirenal hemorrhage in end-stage renal disease treated with selective embolization.

    abstract::Spontaneous nontraumatic rupture of the kidney (Wunderlich syndrome) is an extremely uncommon condition on hemodialysis. We report a case of 44-year-old hemodialysis patient presented with hemorrhagic shock and a right quadrant abdominal pain to the emergency department. There was no history of trauma. A kidney ruptur...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.706887

    authors: Rountas C,Sioka E,Karagounis A,Golphinopoulos S,Kourti P,Stefanidis I,Zacharoulis D,Tzortzis V

    更新日期:2012-01-01 00:00:00

  • Genomic distribution of 5-Hydroxymethylcytosine in mouse kidney and its relationship with gene expression.

    abstract::Ten-Eleven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5hmC). Our recent work found a decline in global 5hmC level in mouse kidney insulted by ischemia reperfusion (IR). However, the genomic distribution of 5hmC in mouse kidney and its relationship with gene expression remai...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2016.1172973

    authors: Wang H,Huang N,Liu Y,Cang J,Xue Z

    更新日期:2016-07-01 00:00:00

  • Hyperkalemia-induced accelerated idioventricular rhythm in a patient with acute renal failure.

    abstract::Electrolyte disorders can alter cardiac ionic currents and depending on the changes can promote proarrhythmic effects. Potassium (K(+)) is the most common intracellular cation related to arrhythmic disorders. Hyperkalemia is mainly seen in the setting of impaired renal function. Severe hyperkalemia may lead to rhythm ...

    journal_title:Renal failure

    pub_type: 信件

    doi:10.3109/0886022X.2011.653752

    authors: Gul EE,Erdogan HI,Yıldırım O,Soylu A,Nikus KC

    更新日期:2012-01-01 00:00:00

  • Factors related to pulse wave velocity and augmentation index in chronic hemodialysis patients.

    abstract:BACKGROUND:Augmentation index (AIx) and pulse wave velocity (PWV) are early markers of atherosclerotic vascular changes and also have been shown to be predictive of cardiovascular disease and total mortality. The aim of our study was to evaluate the relationship between PWV and AIx-HR75, which is the corrected form of ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.615967

    authors: Celik G,Demirci MS,Tumuklu M,Ascı G,Sipahi S,Toz H,Bascı A,Ok E

    更新日期:2011-01-01 00:00:00

  • Elevated plasma levels of PAI-1 predict cardiovascular events and cardiovascular mortality in prevalent peritoneal dialysis patients.

    abstract:BACKGROUND:Elevated plasminogen activator inhibitor-1 (PAI-1) levels are associated with increased cardiovascular (CV) risk in the general population. It has been shown that peritoneal dialysis (PD) patients have increased plasma levels of PAI-1. The aim of this study was to investigate whether PAI-1 independently pred...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220902963772

    authors: Arikan H,Koc M,Tuglular S,Ozener C,Akoglu E

    更新日期:2009-01-01 00:00:00

  • Low-dose IL-2 expands CD4+ regulatory T cells with a suppressive function in vitro via the STAT5-dependent pathway in patients with chronic kidney diseases.

    abstract:BACKGROUND:Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells expansion in vitro from patients with CKD. METHODS:A total of 148 newly di...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2018.1456462

    authors: Li Y,Liu X,Wang W,Wang S,Zhang J,Jiang S,Wang Y,Li L,Li J,Zhang Y,Huang H

    更新日期:2018-11-01 00:00:00

  • Do neutrophil gelatinase-associated lipocalin and interleukin-18 predict renal dysfunction in patients with familial Mediterranean fever and amyloidosis?

    abstract:BACKGROUND:The aim of this study was to evaluate whether neutrophil gelatinase-associated lipocalin (NGAL) and interleukin-18 (IL-18) predict renal disfunction in patients with familial Mediterranean fever (FMF). METHODS:This prospective study consisted of 102 patients with FMF in attack-free period, and 40 matched he...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.865486

    authors: Deveci K,Korkmaz S,Senel S,Deveci H,Sancakdar E,Uslu AU,Deniz A,Alkan F,Seker MM,Sencan M

    更新日期:2014-04-01 00:00:00

  • Low-dose cyclosporine in treatment of membranous nephropathy with nephrotic syndrome: effectiveness and renal safety.

    abstract:BACKGROUND:To observe effectiveness and renal safety of long-term low-dose cyclosporine in idiopathic membranous nephropathy (IMN). METHODS:Sixty-eight patients were enrolled in this prospective cohort study. Renal endpoint was defined as a decrease in eGFR ≥50% from baseline and a development of eGFR ≤60 ml/min/1.73m...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2017.1373130

    authors: Yu X,Ruan L,Qu Z,Cui Z,Zhang Y,Wang X,Meng L,Liu X,Wang F,Zhang Y,Liu G,Yang L

    更新日期:2017-11-01 00:00:00

  • Lipid abnormalities and oxidized LDL in chronic kidney disease patients on hemodialysis and peritoneal dialysis.

    abstract::Dyslipoproteinemia and oxidative modification of low-density lipoprotein (oxLDL) contribute to the development of oxidative stress and atherosclerosis in chronic kidney disease (CKD). On the contrary, high-density lipoprotein cholesterol (HDL-C), especially HDL3-C subtype, has protective effect against oxidative damag...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.641515

    authors: Samouilidou EC,Karpouza AP,Kostopoulos V,Bakirtzi T,Pantelias K,Petras D,Tzanatou-Exarchou H,J Grapsa E

    更新日期:2012-01-01 00:00:00

  • The role of the uncertainty of measurement of serum creatinine concentrations in the diagnosis of acute kidney injury.

    abstract::Uncertainty of measurement is the numeric expression of the errors associated with all measurements taken in clinical laboratories. Serum creatinine concentration is the most common diagnostic marker for acute kidney injury. The goal of this study was to determine the effect of the uncertainty of measurement of serum ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2015.1117925

    authors: Kin Tekce B,Tekce H,Aktas G,Uyeturk U

    更新日期:2016-01-01 00:00:00

  • Creatinine clearance after cimetidine administration: is it useful in the monitoring of the function of transplanted kidney?

    abstract:BACKGROUND:Determination of clearance of endogenous creatinine using its plasma and urinary concentration (standard clearance), Cockroft and Gault formula, or MDRD formula (estimated clearance) is commonly performed for assessment of glomerular filtration rate. Although the evaluation of renal function in this way is u...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701459626

    authors: Kabat-Koperska J,Safranow K,Gołembiewska E,Domanski L,Ciechanowski K

    更新日期:2007-01-01 00:00:00

  • Interleukin-22 attenuates renal tubular cells inflammation and fibrosis induced by TGF-β1 through Notch1 signaling pathway.

    abstract::Transforming growth factor-β1 (TGF-β1) is a crucial factor implicated in the development of renal inflammation and tubulointerstitial fibrosis (TIF). The cytokine interleukin 22 (IL-22) was previously reported to involve in the pathogenesis of chronic inflammatory diseases, however recent studies showed that IL-22 cou...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1753538

    authors: Tang R,Xiao X,Lu Y,Li H,Zhou Q,Kwadwo Nuro-Gyina P,Li X

    更新日期:2020-11-01 00:00:00

  • High mobility group box 1 and tumor growth factor β: useful biomarkers in pediatric patients receiving peritoneal dialysis.

    abstract:BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2016.1216711

    authors: Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

    更新日期:2016-10-01 00:00:00

  • Long-term effects of small doses of calcitriol in hemodialysis patients with moderate secondary hyperparathyroidism.

    abstract::Prevention of secondary hyperparathyroidism (SHPTH) and treatment of the moderate cases by small p.os doses of Vitamin D has not been thoroughly investigated on the long term, while large doses of Vitamin D have been successful in the short term treatment of this entity. We administered calcitriol p.os 0.5-1.0 microgr...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.3109/08860229909066984

    authors: Vlassopoulos D,Noussias C,Revenas K,Hadjilouka-Mantaka A,Arvanitis D,Tzortzis G,Hadjiconstantinou V

    更新日期:1999-03-01 00:00:00

  • Impact of pretreatment with carnitine and tadalafil on contrast-induced nephropathy in CKD patients.

    abstract::Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN).Materials and Methods: The present study consisted of three groups of CKD patients. The first group was control group, who were treate...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2019.1669459

    authors: Armaly Z,Artol S,Jabbour AR,Saffouri A,Habashi N,Abd Elkadir A,Ghattas N,Farah R,Kinaneh S,Nseir W

    更新日期:2019-11-01 00:00:00

  • The evolution of the end-stage renal disease program in Australia.

    abstract::Australia was an early pioneer of national integrated programs for the management of end-stage renal disease (ESRD). From being a leader in numbers of patients per population treated, it is now in the top 15. The Australian program has a high proportion of living patients with functioning transplants and a high propor...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229409044855

    authors: Lawrence JR

    更新日期:1994-01-01 00:00:00

  • The incidence of acute kidney injury in patients with traumatic brain injury.

    abstract::There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in the...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2010.510234

    authors: Moore EM,Bellomo R,Nichol A,Harley N,Macisaac C,Cooper DJ

    更新日期:2010-01-01 00:00:00

  • Acute renal failure and pregnancy: a seventeen-year experience of a Tunisian intensive care unit.

    abstract:PURPOSE:To describe the epidemiologic features of acute renal failure related to pregnancy (PRARF) and to evaluate its prognostic impact. METHODS:Retrospective study conducted in a Tunisian intensive care unit over a period of 17 years (1995-2011). Women were included if they were more than 20 weeks pregnant and were ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.819767

    authors: Bouaziz M,Chaari A,Turki O,Dammak H,Chelly H,Ammar R,Nasri A,Ben Algia N,Bahloul M,Ben Hamida C

    更新日期:2013-10-01 00:00:00

  • Vancomycin-resistant enterococci peritonitis development after shifting from hemodialysis to peritoneal dialysis.

    abstract::Although hemodialysis (HD) patients could develop vancomycin-resistant enterococci (VRE) infection, limited studies of VRE-related peritoneal dialysis (PD) peritonitis have been reported. Here, we document a patient who developed peritonitis for the first time with VRE infection after shifting from HD to PD over 4 wee...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2010.509899

    authors: Chang CM,Liang CC,Yeh HC,Yang YF,Wang IK,Lin HH,Huang CC

    更新日期:2010-01-01 00:00:00

  • Use of alpha-lipoic acid in prevention of contrast-induced nephropathy in diabetic patients.

    abstract::In this prospective study, we aimed to determine the protective antioxidant role of alpha-lipoic acid (ALA) on development of contrast-induced nephropathy (CIN) in diabetic patients undergoing coronary angiography. Seventy-eight diabetic patients undergoing coronary angiography were included. Thirty-nine patients were...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/0886022X.2013.790298

    authors: Cicek M,Yıldırır A,Okyay K,Yazici AC,Aydinalp A,Kanyilmaz S,Muderrisoglu H

    更新日期:2013-01-01 00:00:00

  • Renal stone disease and obesity: what is important for urologists and nephrologists?

    abstract::Currently, obesity has reached an epidemic stage and represents a challenge for health authorities across the globe. Certainly, with emergence of obesity epidemic, we started to see an increase in the prevalence of chronic kidney disease (CKD) and nephrolithiasis. Interestingly, epidemiologic studies have shown that t...

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.3109/0886022X.2012.723777

    authors: Ahmed MH,Ahmed HT,Khalil AA

    更新日期:2012-01-01 00:00:00

  • Challenges in clinical-pathologic correlations: acute tubular necrosis in a patient with collapsing focal and segmental glomerulosclerosis mimicking rapidly progressive glomerulonephritis.

    abstract::Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2010.501931

    authors: Rodamilans MF,Barros LL,Carneiro MM,dos Santos WL,Rocha PN

    更新日期:2010-01-01 00:00:00

  • What has changed in the prevalence of hypertension in dialyzed children during the last decade?

    abstract:BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

    journal_title:Renal failure

    pub_type: 杂志文章,多中心研究

    doi:10.1080/0886022X.2016.1260033

    authors: Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

    更新日期:2017-11-01 00:00:00

  • Thrombotic thrombocytopenic purpura (TTP): initial treatment with plasma exchange plus steroids and immunosuppressive agents for relapsing cases.

    abstract:BACKGROUND:The thrombotic thrombocytopenic purpura (TTP) is a rare disorder with a high mortality rate if untreated or delayed therapy. Whether immediate diagnosis and promptly treated with plasma exchange can change the grave prognosis? METHOD:Retrospective analysis was performed on clinical characteristics and treat...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.1081/jdi-120017440

    authors: Yang CW,Chen YC,Dunn P,Chang MY,Fang JT,Huang CC

    更新日期:2003-01-01 00:00:00

  • Hypocomplementemia is associated with more severe renal disease and worse renal outcomes in patients with ANCA-associated vasculitis: a retrospective cohort study.

    abstract:BACKGROUND:The complement system has been recently proposed to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). This study evaluated the value of serum and kidney deposited C3 in predicting renal outcomes in AAV. METHODS:This was a retrospective study of 47 patients with AAV, who were ca...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2020.1803086

    authors: Chalkia A,Thomas K,Giannou P,Panagiotopoulos A,Hadziyannis E,Kapota A,Gakiopoulou H,Vassilopoulos D,Petras D

    更新日期:2020-11-01 00:00:00

  • The effect of renal replacement therapies on serum gastrointestinal system hormones.

    abstract:BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701643799

    authors: Borazan A,Cavdar Z,Saglam F

    更新日期:2007-01-01 00:00:00

  • External dilator-assisted banding for high-flow hemodialysis arteriovenous fistula.

    abstract::Creation of arteriovenous fistula (AVF) may lead to left ventricle hypertrophy and predispose for development or worsening of heart failure. It was postulated to reduce access blood flow if exceeded 2 L/min or cardiac index was higher than 3.0 L/min/m(2). Numbers of techniques decreasing flow were described. The major...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2016.1184936

    authors: Letachowicz K,Kusztal M,Gołębiowski T,Letachowicz W,Weyde W,Klinger M

    更新日期:2016-08-01 00:00:00

  • Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.832308

    authors: Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

    更新日期:2014-02-01 00:00:00

  • Detection of mature macrophages in urinary sediments: clinical significance in predicting progressive renal disease.

    abstract::The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229809045129

    authors: Hotta O,Kitamura H,Taguma Y

    更新日期:1998-03-01 00:00:00

  • The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.

    abstract:BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701860989

    authors: Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

    更新日期:2008-01-01 00:00:00