Abstract:
:In rat barrel cortex, evoked potentials (EPs) to vibrissa stimulation can be divided into two distinct classes according to the relative contribution of their principal components. Our experiments support the notion that these components can be attributed to activation of two pyramidal cell populations: supra- and infragranular. With well-habituated stimuli EPs are dominated by a component related to the supragranular cells (class 1). However, the first reinforcement of vibrissa stimulation in the classical aversive paradigm favours the appearance of EPs dominated by a component characteristic of infragranular cells which matches with activation in the surround zone of the barrel field (class 2). Similar dynamic changes of the relative occurrence of the two EP classes follow other aversive stimuli, including pressing the animal's ear and restraining a whisker. We hypothesize that neuromodulatory action elicited by contextual stimulation activates all neurons in the principal barrel column, including those providing an output to the surrounding barrels. In the classical conditioning paradigm this mechanism may lead to experience-dependent changes within the intracortical network.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Wróbel A,Kublik E,Musial Pdoi
10.1007/s002210050552subject
Has Abstractpub_date
1998-11-01 00:00:00pages
117-23issue
1-2eissn
0014-4819issn
1432-1106journal_volume
123pub_type
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