Abstract:
:In the base of each temporal lobe in 4 monkeys (Macaca fascicularis) we sectioned the pia mater in an antero-posterior line along the most medial part of the inferior temporal visual association cortex (area TE), lateral to the parahippocampal cortex. This pial section interrupts the blood flow in branches of the posterior cerebral artery which cross the parahippocampal gyrus en route to area TE. Histologically, the brains of 2 of these animals did not show any abnormalities in cresyl violet stained material, apart from the small cortical damage along the line of the pial section itself. Of the remaining two animals, one had a small unilateral infarct in TE and one had bilateral infarcts in TE. All of these animals were impaired in visual discrimination learning, and the severity of impairment was correlated only imperfectly with the severity of infarction. These results show that pial section along the medial boundary of area TE can affect visual discrimination learning without producing large infarcts. Further, since aspiration lesions of the hippocampal formation require the pia mater to be sectioned in a similar way to that reported here, the effects of such aspiration lesions on visual learning and memory may be mediated in part by effects on TE.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Gaffan D,Lim Cdoi
10.1007/BF00228525subject
Has Abstractpub_date
1991-01-01 00:00:00pages
227-31issue
1eissn
0014-4819issn
1432-1106journal_volume
87pub_type
杂志文章abstract::Eye and head movements in the horizontal, frontal and sagittal planes were recorded in the rabbit with a newly developed technique using dual scleral search coils in a rotating magnetic field. The compensatory eye movements elicited by passive sinusoidal oscillation deteriorated for frequencies below 0.1 Hz in the hor...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236282
更新日期:1984-01-01 00:00:00
abstract::Cats with a natural convergent squint were discovered within a colony of normal Mill Hill cats. In two of them single unit recording was undertaken in area 17. The ocular dominance distribution showed a clear disruption of binocularity in both hemispheres. This lack of binocular units was comparable to cats with artif...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236640
更新日期:1983-01-01 00:00:00
abstract::After intracranial transection of the optic nerve in cats the retinal stump of the nerve was injected with HRP. Surviving retinal ganglion cells can be retrogradely labeled at least up to 15.5 months of postoperative survival. ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00261356
更新日期:1985-01-01 00:00:00
abstract::Several non-physiological stimuli (i.e. pharmacological or electrical stimuli) have been shown to induce Fos expression in striatal neurons. In this work, striatal Fos (i.e. Fos-like) expression was studied after physiological stimulation, i.e. motor activity (treadmill running at 36 m/min for 20 min). In rats killed ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005715
更新日期:1997-07-01 00:00:00
abstract::Intracellular recordings from thalamic neurons receiving cerebellar inputs were performed under urethane anesthesia in the rat. A total of 64 neurons were recorded intracellularly with micropipettes filled with 4% biocytin solution (dissolved in 0.5 M K-acetate), and cerebellar-induced EPSPs (CN-EPSPs), the membrane r...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231841
更新日期:1991-01-01 00:00:00
abstract::We have tested the hypothesis that complex cell receptive fields are made up of subfields which, for a given cell, have either exclusively even or exclusively odd symmetry. To do this we have measured the response of complex cells in the visual cortex of the cat to members of pairs of spatially limited even-symmetric ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248791
更新日期:1987-01-01 00:00:00
abstract::Peak grip aperture has often been used to quantify the influence of illusions on judgments of size for action. However, a larger peak grip aperture need not mean that the object looks larger. It could also mean that it was grasped more carefully. These two possibilities can be distinguished on the basis of the velocit...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0744-8
更新日期:2007-01-01 00:00:00
abstract::Supernumerary phantom limb (SPL) designates the experience of an illusory additional limb occurring after brain damage. Functional neuroimaging during SPL movements documented increased response in the ipsilesional supplementary motor area (SMA), premotor cortex (PMC), thalamus and caudate. This suggested that motor c...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5044-y
更新日期:2017-10-01 00:00:00
abstract::Human subjects attempted to modify their vestibuloocular reflex (VOR) in the dark by fixating imagined targets while experiencing predictable (SIN) sinusoidal (0.01-2.5 Hz) and unpredictable (SSN) sum of sines rotational stimuli (0.02-1.9 Hz). Modification was attempted under 2 instructional sets: VOR enhancement, ie ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236931
更新日期:1985-01-01 00:00:00
abstract::Previous work has highlighted the role of haptic feedback for manual dexterity, in particular for the control of precision grip forces between the index finger and thumb. It is unclear how fine motor skills involving more than just two digits might be affected, especially given that loss of sensation from the hand aff...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05583-2
更新日期:2019-09-01 00:00:00
abstract::When walking with a hand-held object, grip force is coupled in an anticipatory manner to changes in inertial force resulting from the accelerations and decelerations of gait. However, it is not known how grip and inertial forces are organized at the onset of gait, and if the two forces are coupled in the early phases ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1476-8
更新日期:2008-09-01 00:00:00
abstract::The amyloid precursor protein (APP) has a pivotal role in pathogenesis of Alzheimer's disease (AD) via its beta- and gamma-secretase-derived cleavage products--the A-beta peptides. An alternative processing pathway provided by the alpha-secretase prevents formation of those toxic peptides and gives rise to the neurotr...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2885-7
更新日期:2012-04-01 00:00:00
abstract::The afferent volley generated during neuromuscular electrical stimulation (NMES) can increase the excitability of the human corticospinal (CS) pathway. This study was designed to determine the effect of different frequencies of NMES applied over the common peroneal nerve on changes in CS excitability for the tibialis ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2202-x
更新日期:2010-05-01 00:00:00
abstract::Single neurons in the inferior colliculus of the Greater Horseshoe bat, Rhinolophus ferrumequinum, showed two broad categories of response patterns to sinusoidally frequency (SFM) or amplitude (SAM) modulated stimuli. Tonic responding cells (best excitatory frequency (BEF) between 10 and 90 kHz) showed a rough sinusoi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238345
更新日期:1979-01-02 00:00:00
abstract::A photograph of an action contains implicit information about the depicted motion. Previous studies using either psychophysics or neuroimaging suggested that the neural processing of implied-motion images shares some features of real-motion processing. According to the hypothesis that the target depicted in photograph...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2598-y
更新日期:2011-04-01 00:00:00
abstract::It is known that attending to a cutaneous stimulus briefly increases its subjective intensity. The purpose of the present study was to determine whether an extended period of attention would produce a longer-lasting perceptual amplification. Eighty subjects were assigned alternately to experimental and control groups....
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05910-y
更新日期:2020-11-05 00:00:00
abstract::The effect of the intermittency of visual information in the bimanual coordination of an isometric force coordination task was investigated as a function of criterion force level. Eight levels of visual information intermittency (.2-25.6 Hz) were used in blocked fashion at each force level. Participants were required ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4606-8
更新日期:2016-07-01 00:00:00
abstract::This study compared the mechanisms of adaptation to stable and unstable dynamics from the perspective of changes in joint mechanics. Subjects were instructed to make point to point movements in force fields generated by a robotic manipulandum which interacted with the arm in either a stable or an unstable manner. Afte...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-003-1443-3
更新日期:2003-07-01 00:00:00
abstract::Dementia due to cerebral ischemic lesions is relatively common in the elderly. Since many of these lesions are probably caused by emboli, studying emboli-induced cerebral lesions in rabbits should, hopefully, provide information that is useful when searching for a means of preventing and treating vascular dementia in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050622
更新日期:1999-01-01 00:00:00
abstract::We investigated the effect of different spatial and temporal parameters on the saccadic reaction times (SRTs) of the antisaccades and on the frequency and the SRTs of erratic prosaccades in five adult human subjects. The subjects were instructed to aim their saccades to the side opposite to where a visual go-stimulus ...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/pl00005749
更新日期:1997-09-01 00:00:00
abstract::The capacity to acquire motor skills through repeated practice of a sequence of movements underlies many everyday activities. Extensive research in humans has dealt with the importance of spatial and temporal factors on motor sequence learning, standing in contrast to the few studies available in animals, particularly...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2839-0
更新日期:2011-10-01 00:00:00
abstract::We studied the finger interactions during maximum voluntary force (MVF) production in flexion and extension in children and adults. The goal of this study was to investigate the age-related changes and flexion-extension differences of MVF and finger interaction indices, such as finger inter-dependency (force enslaving...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0629-x
更新日期:2007-01-01 00:00:00
abstract::Large neurons of the mouse caudate nucleus contain profuse Nissl material, have a maximal pole-to-pole diameter of up to 25 micron, occur preferentially within a central or CORE zone of the neostriatum, and are almost always located within territories delimited by medium-sized clustered neurons. Examination of coronal...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235886
更新日期:1982-01-01 00:00:00
abstract::We have shown before that subjects exposed to a changed gravitoinertial environment produce exaggerated manual forces. From the observed pattern of findings, we argued that initial forces were exaggerated because of abnormal vestibular activity and peak forces because of degraded proprioceptive feedback. If so, only p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-2999-6
更新日期:2012-04-01 00:00:00
abstract::The purpose of this study was to investigate the relationship between EEG-derived motor activity-related cortical potential (MRCP) and voluntary muscle activation. Eight healthy volunteers participated in two experimental sessions. In one session, subjects performed isometric elbow-flexion contractions at four intensi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000382
更新日期:2000-08-01 00:00:00
abstract::This study documents a bilateral projection from nucleus reticularis tegmenti pontis (NRTP) to the rostral aspect of the medial vestibular nucleus (MVN) in rabbits. Horseradish peroxidase injections in rostral MVN produced retrogradely labeled neurons in the caudal half of NRTP; caudal MVN injections produced negative...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237207
更新日期:1983-01-01 00:00:00
abstract::In the lateral septal area (LSA), both inhibitory and excitatory dopamine (DA) actions, as well as hypothalamic and midbrain DA efferents, have been described. Some neurons of the hypothalamic and midbrain DA systems contain somatostatin (SOM) or neurotensin (NT), and, in the LSA, the distribution of fibers containing...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229030
更新日期:1993-01-01 00:00:00
abstract::Adrenocortical responses, as expressed by changes in plasma corticosterone levels, following ether stress and dorsal hippocampal stimulation, were studied in intact rats and in rats with complete, anterior of posterior hypothalamic deafferentations. Ether stress produced normal responses in all experimental groups. In...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237345
更新日期:1981-01-01 00:00:00
abstract::It is a common experience, immediately after the removal of a cast or a splint, to feel motor awkwardness, which is usually attributed to muscular and joint immobilization. However, the same feeling may also be perceived after a brief period of immobilization. We provide evidence that this last effect stems from chang...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3115-7
更新日期:2012-07-01 00:00:00
abstract::Postural instability evokes cortical and autonomic reactions in addition to the primary compensatory response, and it is hypothesized that these responses may be related to underlying affective influences such as tonic physiological arousal. The purpose of this study was to determine whether perturbation-evoked cortic...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2257-8
更新日期:2010-06-01 00:00:00