Abstract:
:Large neurons of the mouse caudate nucleus contain profuse Nissl material, have a maximal pole-to-pole diameter of up to 25 micron, occur preferentially within a central or CORE zone of the neostriatum, and are almost always located within territories delimited by medium-sized clustered neurons. Examination of coronal sections taken through the head of the nucleus and stained with cresyl violet revealed the absence of age-related pathology as evaluated by three parameters: (1) there was no statistically significant difference in the frequency of large neurons in all areas of the head of the nucleus; (2) the large neuron continued to be confined preferentially to the CORE zone of the head of the nucleus throughout the time period studied; and (3) no statistically significant shifts were detected in the geometry of large cell-medium cell clusters. Since postnatal age did not significantly affect the frequency, distribution or geometry of large cell-medium cell clusters, data from all animals was combined. This information was used to evaluate the possibility of an interaction between location within or outside the CORE zone and type of large cell-medium cell cluster, but these results were not statistically significant. Therefore, the data analyzed in this study support the view that the geometry of large cell-medium cell clusters is extremely stable in the mouse neostriatum and seems not to be influenced either by age of the animal or by location of the cell grouping.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Mensah PLdoi
10.1007/BF00235886subject
Has Abstractpub_date
1982-01-01 00:00:00pages
57-60issue
1eissn
0014-4819issn
1432-1106journal_volume
47pub_type
杂志文章abstract::The efferent projections of the five histaminergic neuronal subgroups in the tuberomammillary nucleus to the medial preoptic area (MPO) and inferior colliculus (IC) were examined by immunocytochemistry with antihistidine decarboxylase (HDC) antibodies combined with retrograde axonal tracing with Fast Blue (FB). The te...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228164
更新日期:1990-01-01 00:00:00
abstract::The position of the center of gravity (CG) is a reference value that is controlled by the nervous system during the performance of movements. In order to maintain equilibrium, leg movement is preceded by a shift of the CG towards the supporting side. This CG shift is initiated by an early displacement of the center of...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050453
更新日期:1998-07-01 00:00:00
abstract::The time course of local changes of the extracellular space (ES) was investigated by measuring concentration changes of repeatedly injected tetramethylammonium (TMA+) and choline (Ch+) ions for which cell membranes are largely impermeable. After stimulus-induced extracellular [K+] elevations the delta [TMA+] and delta...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236151
更新日期:1980-01-01 00:00:00
abstract::The relationship between phantom limb phenomena and cortical reorganization was examined in five subjects with congenital absence of an upper limb and nine traumatic amputees. Neuromagnetic source imaging revealed minimal reorganization of primary somatosensory cortex in the congenital amputees (M=0.69 cm, SD 0.24) an...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050334
更新日期:1998-03-01 00:00:00
abstract::The aim of this study was to investigate the effect of single joint displacement on the pattern of leg muscle electromyographic (EMG) activity during locomotion. For the first time, unilateral rotational hip or knee joint displacements were applied by a driven orthotic device at three phases of swing during locomotion...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-1904-3
更新日期:2004-10-01 00:00:00
abstract::The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231857
更新日期:1991-01-01 00:00:00
abstract::Mental practice (MP) is a promising adjuvant to physical practice that involves many of the same mechanisms and takes on many of the same properties as physical practice. This study compared efficacy of a "massed" MP regimen versus a "distributed" MP regimen on upper extremity (UE) motor impairment and functional limi...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-016-4686-5
更新日期:2016-10-01 00:00:00
abstract::It has recently been suggested that time perception and motor timing are influenced by the presence of biological movements and animacy in the visual scene. Here, we investigated the interactions among timing, speed and animacy in two experiments. In Experiment 1, observers had to press a button in synchrony with the ...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3338-7
更新日期:2013-02-01 00:00:00
abstract::To determine if PAG stimulation activates serotonin containing neurons in RM, intracellular techniques were used to identify raphe magnus (RM) cells that are excited by antinociceptive periaqueductal gray (PAG) stimulation in the cat. RM neurons that received a monosynaptic EPSP from PAG shock were intracellularly lab...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00279654
更新日期:1988-01-01 00:00:00
abstract::Adrenocortical responses, as expressed by changes in plasma corticosterone levels, following ether stress and dorsal hippocampal stimulation, were studied in intact rats and in rats with complete, anterior of posterior hypothalamic deafferentations. Ether stress produced normal responses in all experimental groups. In...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237345
更新日期:1981-01-01 00:00:00
abstract::The fate of monoclonal anti-vasopressin antibodies (VP-MAbs) injected in vivo into the paraventricular nucleus (PVN) of the rat brain was studied by immunocytochemistry. Depending on the post survival time, VP-MAbs contained in an ascites fluid were stained at different levels of the VP neurons: the cytoplasm of the P...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235986
更新日期:1987-01-01 00:00:00
abstract::In classic conditioning, the interstimulus interval (ISI) between the conditioned (CS) and unconditioned (US) stimulus is a critical parameter. The aim of the present experiment was to assess whether, during conditioning, modification of the CS-US interval could reliably produce changes in the functional properties of...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900290
更新日期:2000-06-01 00:00:00
abstract::Previous studies reported that the activity of trigeminal motoneurons innervating masseter muscles is modulated by vestibular inputs. We performed the present study to provide an anatomical substrate for these physiological observations. The transynaptic retrograde tracer pseudorabies virus-Bartha was injected into mu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0275-8
更新日期:2006-05-01 00:00:00
abstract::In many daily situations, balance control is associated with a cognitive activity such as reading or a simple calculation. The objective of this study was to investigate the relationship between these two specific human activities, especially the influence of visual cues and support surface stability on body sway duri...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3913-1
更新日期:2014-07-01 00:00:00
abstract::The presence of discrete events during an interval to be estimated generally causes a dilation of perceived duration (event-filling effect). Here, we investigated this phenomenon in the thermal modality using multi-seconds (19 s) innocuous cool stimuli that were either constant (continuous interval) or fluctuating to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4537-9
更新日期:2016-04-01 00:00:00
abstract::The spatial properties of human binocular mechanisms were investigated using the technique of subthreshold summation. Isolation of binocular mechanisms was achieved by means of interocular stimulus presentation. The contrast detection threshold for a sinusoidal test grating viewed by one eye was found to be reduced by...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237700
更新日期:1977-02-16 00:00:00
abstract::The human visual system is strikingly insensitive to speed changes attributed to the need to infer visual acceleration, observed during stationary fixation, indirectly by comparing velocities integrated over time. The objective of this study was to test if smooth pursuit eye movements improve the detection of speed ch...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0216-6
更新日期:2006-04-01 00:00:00
abstract::In situ hybridization was used to study the expression of prepro-neuropeptide Y (NPY), preprosomatostatin (SOM), preprotachykinin (PPT) and preprocholecystokinin (CCK) mRNA in caudate-putamen and frontoparietal cortex of rat brain with unilateral lesion of midbrain dopamine neurons. Neurons expressing NPY and SOM mRNA...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227990
更新日期:1990-01-01 00:00:00
abstract::Sudden limb displacement evokes a complex sequence of compensatory muscle activity. Following the short-latency reflex and preceding voluntary reactions is an epoch termed the medium-latency reflex (MLR) that could reflect spinal processing of group II muscle afferents. One way to test this possibility is oral ingesti...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5162-6
更新日期:2018-03-01 00:00:00
abstract::If horizontal saccades or smooth-pursuit eye movements are made with the line-of-sight at different elevations, the three-dimensional (3D) angular rotation axis of the globe tilts by half the vertical eye eccentricity. This phenomenon is named "half-angle rule" and is a consequence of Listing's law. It was recently fo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050943
更新日期:1999-11-01 00:00:00
abstract::The evidence on the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on action restraint on Go/NoGO reaction time (RT) tasks in Parkinson's disease (PD) is inconsistent; with some studies reporting no effect and others finding that STN stimulation interferes with withholding of responses and results in m...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4531-2
更新日期:2016-04-01 00:00:00
abstract::The purpose of this study was to investigate whether repetitive electrical stimulation of the common peroneal nerve (CPN) is associated with changes in the motor response of the tibialis anterior (TA) muscle elicited by focal magnetic stimulation of the motor cortex. Motor evoked potentials (MEP) with a stimulation in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1094-9
更新日期:2002-08-01 00:00:00
abstract::Vection is the illusion of self-motion in the absence of real physical movement. The aim of the present study was to analyze how multisensory inputs (visual and auditory) contribute to the perception of vection. Participants were seated in a stationary position in front of a large, curved projection display and were e...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3793-9
更新日期:2014-03-01 00:00:00
abstract::The purpose of this study was to investigate the time-course of corticospinal excitability during reaction time (RT), and compare the excitability when a precue provided information regarding both the direction and extent of the upcoming movement ('Full' condition), specified the direction of the upcoming movement onl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1772-2
更新日期:2004-05-01 00:00:00
abstract::It is a conservative and reasonable suggestion that implicit functioning, as in blindsight, is simply a weakened, degraded form of normal functioning, especially as the parameters of vision in blindsight are themselves weakened--e.g., acuity is reduced, detection thresholds are raised, chromatic discrimination is coar...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-008-1388-7
更新日期:2009-01-01 00:00:00
abstract::We examined opioid binding in fractions with disconnected nerve endings (secretosomes) which were prepared from porcine neurohypophyses by centrifugation in a discontinuous Percoll gradient. Specific (= displaceable) binding was observed with 3H-etorphine and with 3H-diprenorphine, two ligands with low selectivity for...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00271856
更新日期:1988-01-01 00:00:00
abstract::Local anesthetic may cause neurotoxicity in developing neurons. In this study, we examined the molecular mechanisms of microRNA-210 (miR-210) in regulating bupivacaine-induced dorsal root ganglia (DRG) neurotoxicity in vitro. Young mouse (P30) DRG explants were cultured in vitro and treated with 5 mM bupivacaine to in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4513-4
更新日期:2016-04-01 00:00:00
abstract::The present study aimed at determining whether the observation of two functionally compatible artefacts, that is which potentially concur in achieving a specific function, automatically activates a motor programme of interaction between the two objects. To this purpose, an interference paradigm was used during which a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3047-2
更新日期:2012-05-01 00:00:00
abstract::We examined the synaptic connections between pairs of Bötzinger-complex, bulbospinal expiratory neurons in decerebrate rats. All were antidromically activated from the spinal cord at the C2-C3 border. Cross-correlation histograms of 18 ipsilateral pairs showed troughs on both sides of time zero (8) and to one side of ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050701
更新日期:1999-04-01 00:00:00
abstract::Functional decline in locomotion is common among the elderly, and the prevalence of gait disorders increases with age. Recently, increasing interest has been focused on the influence of age-related decline in brain function and neurological disorders such as dementia and Alzheimer's disease on gait capacity. However, ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1643-y
更新日期:2009-03-01 00:00:00