Abstract：
:Electrical activity of neurons in rat hypothalamic ventromedial nucleus was recorded in tissue slices, to investigate central neural mechanisms underlying reduction of food intake caused by TRH and its metabolite, cyclo(His-Pro) [cHP]. Application of TRH had two actions: stimulation of neuronal activity, which was desensitized on closely repeated applications; and modulation of neuronal responses to neurotransmitters, even in the absence of the stimulatory action. The neuromodulatory but not the direct stimulatory action could also be achieved by cHP. The neuromodulatory action is more likely to be a neural mechanism underlying the inhibition of feeding, while other biological functions, unique to TRH, may depend on direct stimulation. In this way, TRH could achieve different biological results through different modes of action on hypothalamic neurons.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Kow LM,Pfaff DWdoi
10.1007/BF00269457subject
Has Abstractpub_date
1987-01-01 00:00:00pages
93-9issue
1eissn
0014-4819issn
1432-1106journal_volume
67pub_type
杂志文章abstract：:The ventral medulla oblongata of rats was analyzed with a double-labelling immunofluorescence technique using guinea pig antibodies directed against serotonin (5-HT) and rabbit antisera directed against enkephalin (ENK). Numerous cells in the region of nucleus raphe obscurus, nucleus raphe pallidus and nucleus raphe m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00249904
更新日期：1989-01-01 00:00:00
abstract：:This study examined the hypothesis that the mirror reflection of one hand's movement directly influences motor output of the other (hidden) hand, during performance of bimanual drawing. A mirror was placed between the two hands during bimanual circle drawing, with one hand and its reflection visible and the other hand...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1831-3
更新日期：2004-07-01 00:00:00
abstract：:The current study examines the modulation of the motion-onset response based on the frequency-range of sound stimuli. Delayed motion-onset and stationary stimuli were presented in a free-field by sequentially activating loudspeakers on an azimuthal plane keeping the natural percept of externalized sound presentation. ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5329-9
更新日期：2018-10-01 00:00:00
abstract：:1.) Eye movements were recorded in four Java monkeys (M. fascicularis) after unilateral microinjections (1 microliter, concentration 1 micrograms/microliter) of the GABA antagonist, bicuculline, and the GABA agonist, muscimol, into oculomotor related regions of the vestibular nuclei. Eye movements were investigated in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228958
更新日期：1991-01-01 00:00:00
abstract：:We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3090-z
更新日期：2012-06-01 00:00:00
abstract：:When the head rotates, vestibulocollic reflexes counteract the rotation by causing contraction of the neck muscles that pull against the imposed motion. With voluntary head rotations, these same muscles contract and assist the movement of the head. The purpose of this study was to determine if an infinite variety of m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02259112
更新日期：1992-01-01 00:00:00
abstract：:Selective attention is popularly assessed with colour Stroop tasks in which participants name the ink colour of colour words, whilst resisting interference from the natural tendency to read the words. Prior studies hinted that the key brain regions (dorsolateral prefrontal (dlPFC) and anterior cingulate cortex (ACC)) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2225-3
更新日期：2010-05-01 00:00:00
abstract：:Vision can improve bipedal upright stability during standing and locomotion. However, during locomotion, vision supports additional behaviors such as gait cycle modulation, navigation, and obstacle avoidance. Here, we investigate how the multiple roles of vision are reflected in the dynamics of trunk control as the ne...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2414-0
更新日期：2010-10-01 00:00:00
abstract：:The objective of this study was to investigate interhemispheric transcallosal connections between primary motor cortices noninvasively in awake human subjects. For this purpose, focal transcranial magnetic stimulation was performed on eight healthy, right-handed subjects and one patient with congenital collosal agenes...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227944
更新日期：1996-12-01 00:00:00
abstract：:Using combined psychophysics and event-related potentials (ERPs), we investigated the effect of perceptual learning on face gender discrimination and probe the neural correlates of the learning effect. Human subjects were trained to perform a gender discrimination task with male or female faces. Before and after train...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3396-x
更新日期：2013-04-01 00:00:00
abstract：:The electrophysiological responses of 162 tectal cells to computer-generated visual stimuli were extracellularly recorded from 24 homing pigeons before and after injecting either lidocaine or N-methyl-D-aspartate (NMDA) into the nucleus isthmi pars magnocellularis (Imc) or the nucleus isthmi pars parvocellularis (Ipc)...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231973
更新日期：1995-01-01 00:00:00
abstract：:The firing of tuberoinfundibular neurones antidromically identified as projecting to the median eminence was recorded during electrical stimulation of the preoptic and/or anterior hypothalamic areas (PO/AH) of the rostral hypothalamus. Parameters of stimulation were chosen which are known to cause increased secretion ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237074
更新日期：1980-01-01 00:00:00
abstract：:There are important developmental changes occurring during infancy in visual cortical structures that underlie higher-order perceptual abilities. Using high-density electrophysiological recording techniques, the present study aimed to examine the development of visual mechanisms, during the first year of life, associa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0854-y
更新日期：2007-06-01 00:00:00
abstract：:The results of this study show that the different receptive fields of multisensory neurons in the cortex of the cat anterior ectosylvian sulcus (AES) were in spatial register, and it is this register that determined the manner in which these neurons integrated multiple sensory stimuli. The functional properties of mul...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227844
更新日期：1992-01-01 00:00:00
abstract：:The behavioral relevance of neuronal activity in primate area MT for motion perception and control of visually guided eye movements is well documented. The projections of area MT comprise connections to subcortical structures and to the parietal network, both of which play a role in visuospatial transformation for gui...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1771-z
更新日期：2009-12-01 00:00:00
abstract：:To measure dynamic visuo-motor coupling within the two hemispheres, we showed observers an animation of a rotating cup. They indicated with left or right buttons when a fixation dot in the center of the animation changed color. For either hand, response times changed continuously with the irrelevant position of the cu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0781-3
更新日期：2007-01-01 00:00:00
abstract：:Human subjects can readily adapt their movement trajectories to different dynamic or visuomotor environments. The focus of the current study was to determine whether subjects could simultaneously adapt to multiple dynamic environments. Subjects ( n=5) drew ellipses continuously for 70 s using a torquable manipulandum ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1260-0
更新日期：2003-01-01 00:00:00
abstract：:Vibration on localised areas of skin can be used to signal spatial orientation, multi-directional motion and also to guide arm and hand movements. This study investigated the possibility that vibration at loci on the skin might also be used to cue gaze direction. Eight subjects made eye or (head + eye) gaze saccades i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1231-6
更新日期：2008-03-01 00:00:00
abstract：:The effects of electrical stimulation of the cerebral cortex on the monosynaptic jaw closing and the disynaptic jaw opening reflexes were studied in cats anaesthetized with chloralose. The time course of the reflex effects was recorded. Similar rhythmic sequences of facilitation and inhibition were observed in both re...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237546
更新日期：1980-01-01 00:00:00
abstract：:The phase of the angular vestibulo-ocular reflex (VOR) is subject to adaptive control. We had previously found that adapting the phase of the VOR also produced changes in drift on eccentric gaze-holding, implying a change in the time constant of the velocity-to-position neural integrator. Here we attempted to dissocia...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s002210050392
更新日期：1998-05-01 00:00:00
abstract：:Human subjects attempted to modify their vestibuloocular reflex (VOR) in the dark by fixating imagined targets while experiencing predictable (SIN) sinusoidal (0.01-2.5 Hz) and unpredictable (SSN) sum of sines rotational stimuli (0.02-1.9 Hz). Modification was attempted under 2 instructional sets: VOR enhancement, ie ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236931
更新日期：1985-01-01 00:00:00
abstract：:Prevention of testosterone aromatization in the female rat pups by perinatal treatment with 1,4,6 androstatriene-3,17-dione (ATD) induces an important defeminization as shown by a reduction of fluctuations of LH release after castration and estradiol implantation. The fact that, under our in vitro experimental conditi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00340477
更新日期：1986-01-01 00:00:00
abstract：:The egocentric localization of objects in extrapersonal space requires that the retinal and extraretinal signals specifying the gaze direction be simultaneously processed. The question as to whether the extraretinal signal is of central or peripheral origin is still a matter of controversy, however. Three experiments ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229419
更新日期：1991-01-01 00:00:00
abstract：:Intermodal attention (IA) is assumed to allocate limited neural processing resources to input from one specific sensory modality. We investigated effects of sustained IA on the amplitude of a 40-Hz auditory (ASSR) and a 4.3-Hz visual steady-state response (VSSR). To this end, we concurrently presented amplitude-modula...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2667-2
更新日期：2011-09-01 00:00:00
abstract：:We recorded from 389 "reach" neurons (two monkeys) in the superior colliculus (SC) and underlying reticular formation (RF) or adjacent periaqueductal grey, whose activity was related to visually guided arm movements. Reach neurons were present from approximately 0.7 mm down to a depth of 6 mm below the surface of the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005691
更新日期：1997-06-01 00:00:00
abstract：:Although maintenance of steady contractions is required for many daily tasks, there is little understanding of brain areas that modulate lower limb force accuracy. Functional magnetic resonance imaging was used to determine brain areas associated with steadiness and force during static (isometric) lower limb target-ma...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3976-z
更新日期：2014-10-01 00:00:00
abstract：:Experiments were done to investigate the role of glutamatergic systems in the median preoptic nucleus (MnPO) in the water ingestion induced by administration of angiotensin II (ANG II) in the subfornical organ (SFO) in the awake rat. Microdialysis methods were utilized to quantify the extracellular content of glutamat...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05681-1
更新日期：2020-01-01 00:00:00
abstract：:The retinal positions of objects in the world change with each eye movement, but we seem to have little trouble keeping track of spatial information from one fixation to the next. We examined the role of attention in trans-saccadic localization by asking participants to localize targets while performing an attentional...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4062-2
更新日期：2014-12-01 00:00:00
abstract：:Saccades are known to influence subsequent arm movements. There is less information to suggest that the characteristics of saccades depend on the reaching movements they accompany. To explore this issue, we studied the systematic errors of saccades generated by two adult female Rhesus monkeys (Macaca Mulata), which we...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1427-4
更新日期：2008-08-01 00:00:00
abstract：:Intracortical inhibition was investigated in normal human volunteers by paired-pulse transcranial magnetic stimulation, using a new, computer-assisted threshold-tracking method. Motor threshold was defined as the stimulus amplitude required to evoke a motor evoked potential of 0.2 mV (peak-to-peak) in abductor pollici...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0988-2
更新日期：2002-03-01 00:00:00
