Abstract:
:Prevention of testosterone aromatization in the female rat pups by perinatal treatment with 1,4,6 androstatriene-3,17-dione (ATD) induces an important defeminization as shown by a reduction of fluctuations of LH release after castration and estradiol implantation. The fact that, under our in vitro experimental conditions, ATD is able to displace testosterone binding in the hypothalamus whereas estradiol does not, confirms the hypothesis that ATD acts on aromatase. The most attractive explanation for the defeminization effect of ATD is then an estrogen-like action of ATD.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Slama A,Gogan F,Sarrieau A,Vial M,Rostene W,Kordon Cdoi
10.1007/BF00340477subject
Has Abstractpub_date
1986-01-01 00:00:00pages
407-10issue
3eissn
0014-4819issn
1432-1106journal_volume
64pub_type
杂志文章abstract::In two monkeys, we measured the initial vergence eye movements elicited by sudden forward motion on a linear sled. Animals faced a tangent screen and experienced the translation while in darkness, fixating a small, centered spot, or viewing a large-field pattern. Forward movements elicited convergent responses that we...
journal_title:Experimental brain research
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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更新日期:2012-03-01 00:00:00
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journal_title:Experimental brain research
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更新日期:2018-03-01 00:00:00
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journal_title:Experimental brain research
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