Abstract：
:A central network of neurones in the spinal cord has been shown to produce a rhythmic motor output similar to locomotion after suppression of all afferent inflow. The experiments were performed mainly in acute spinal cats (th. 12), which had received DOPA i.v. and the monoamine oxidase inhibitor Nialamide. In some preparations all dorsal roots supplying the spinal cord were transected, in others phasic afferent activity was suppressed by curarization. The activity was recorded as neurograms from nerve filaments or as electromyograms. It is concluded that: 1. alternating activity between flexors and extensors of foot, ankel, knee, and hip of one limb can still occur 2. the duration of the flexor discharges vary less with the cycle duration than the extensor discharges 3. different flexor muscles may retain individual patterns 4. the activity at different joints can be dissociated 5. there is at least one network for each limb. 6. the coordination between the two hindlimbs can be alternating as in walking or be more closely spaced as in galloping 7. alternating activity in the ankle remains even when only segments L6, L7 and S1 are intact.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Grillner S,Zangger Pdoi
10.1007/BF00235671subject
Has Abstractpub_date
1979-01-15 00:00:00pages
241-61issue
2eissn
0014-4819issn
1432-1106journal_volume
34pub_type
杂志文章abstract：:Prevention of testosterone aromatization in the female rat pups by perinatal treatment with 1,4,6 androstatriene-3,17-dione (ATD) induces an important defeminization as shown by a reduction of fluctuations of LH release after castration and estradiol implantation. The fact that, under our in vitro experimental conditi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00340477
更新日期：1986-01-01 00:00:00
abstract：:Motor learning results from repeated exposure to the same movement and allows a mover to increase movement optimality. Typically, this has only been considered in single-step movements. In sequential movements, an initial reach movement is tailored to the demands of the onward movement. However, the exact role of moto...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3728-5
更新日期：2014-01-01 00:00:00
abstract：:In general, social neuroscience research tends to focus on visual and auditory channels as routes for social information. However, because the skin is the site of events and processes crucial to the way we think about, feel about, and interact with one another, touch can mediate social perceptions in various ways. Thi...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-009-2007-y
更新日期：2010-07-01 00:00:00
abstract：:The firing of tuberoinfundibular neurones antidromically identified as projecting to the median eminence was recorded during electrical stimulation of the preoptic and/or anterior hypothalamic areas (PO/AH) of the rostral hypothalamus. Parameters of stimulation were chosen which are known to cause increased secretion ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237074
更新日期：1980-01-01 00:00:00
abstract：:This study exploited the alterations in pedal speed and joints kinematics elicited by changing crank length (CL) to test how altered task mechanics during cycling will modulate the muscle activation characteristics in human rectus femoris (RF), biceps femoris long head (BF), soleus (SOL) and tibialis anterior (TA). Ki...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1561-y
更新日期：2003-10-01 00:00:00
abstract：:Vision can improve bipedal upright stability during standing and locomotion. However, during locomotion, vision supports additional behaviors such as gait cycle modulation, navigation, and obstacle avoidance. Here, we investigate how the multiple roles of vision are reflected in the dynamics of trunk control as the ne...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2414-0
更新日期：2010-10-01 00:00:00
abstract：:Quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3H] muscimol (specific GABAA receptor ligand) binding in the male Japanese quail brain. In gonadally intact Japanese quail brains, [3H] muscimol revealed a heterogeneous distribution with high GABAA receptor level...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227088
更新日期：1991-01-01 00:00:00
abstract：:Joint stiffness measurements during small transient perturbations have suggested that stiffness during movement is different from that observed during posture. These observations are problematic for theories like the classical equilibrium point hypothesis, which suggest that desired trajectories during movement are en...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000598
更新日期：2001-02-01 00:00:00
abstract：:Stair walking is a challenging locomotor task, and visual information about the steps is considered critical to safely walk up and down. Despite the importance of such visual inputs, there remains relatively little information on where gaze is directed during stair walking. The present study investigated the role of v...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2520-z
更新日期：2011-03-01 00:00:00
abstract：:A number of perceptual and neurophysiological studies have investigated the effects of delivering unilateral versus bilateral tactile sensory stimulation. While a number of studies indicate that perceptual discrimination degrades with opposite-hand stimulation, there have been no reports that examined the digit specif...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4045-3
更新日期：2014-11-01 00:00:00
abstract：:Volume conduction measurements were carried out the brachial biceps, tibialis anterior and deltoid, in normal human subjects. Attenuation constant K and time constant tau of the muscle tissue transfer function were measured, and the average electrode uptake area calculated for the three muscles. The average number of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238380
更新日期：1981-01-01 00:00:00
abstract：:A task has been developed to investigate the ability of cats to switch the direction of an ongoing target-reaching forelimb movement with the aid of a visual cue. The cats were standing in front of two horizontal tubes (internal diameter 30 mm; shoulder level) with food. The entrances of the tubes were closed with opa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228841
更新日期：1990-01-01 00:00:00
abstract：:In earlier studies the tetrahydroisoquinoline derivative N-methyl-norsalsolinol (2-MDTIQ) was discovered in lumbar cerebrospinal fluid and brain of patients with Parkinson's disease. To establish whether 2-MDTIQ is toxic to the dopaminergic system, 2-MDTIQ or 6-hydroxydopamine (6-OHDA) were stereotactically injected i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227181
更新日期：1996-11-01 00:00:00
abstract：:Extracellular Ca2+ activity (aCa) changes were measured with Ca2+-sensitive microelectrodes in the cat cerebral cortex during iontophoretic administration of excitatory and inhibitory aminoacids. Glutamate, aspartate and DL homcysteate usually decreased aCa from a baseline of 1.3 mM to as low as 0.1 mM. The amplitude ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237788
更新日期：1980-01-01 00:00:00
abstract：:To promote motor learning, robotic devices have been used to improve subjects' performance by guiding desired movements (haptic guidance-HG) or by artificially increasing movement errors to foster a more rapid learning (error amplification-EA). To better understand the neurophysiological basis of motor learning, a few...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5365-5
更新日期：2018-11-01 00:00:00
abstract：:Transcranial magnetic stimulation (TMS) has been first described 30 years ago, and since then has gained enormous attention by neurologists, psychiatrists, neurosurgeons, clinical neurophysiologists, psychologists, and neuroscientist alike. In the early days, it was primarily used to test integrity of the corticospina...
journal_title：Experimental brain research
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00221-016-4865-4
更新日期：2017-04-01 00:00:00
abstract：:Functional magnetic resonance imaging was used to explore the neural correlates of semantic judgments to Chinese characters. Adult participants were asked to indicate if character pairs were related in meaning that were arranged in a continuous variable according to association strength. This parametric manipulation a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1942-y
更新日期：2009-10-01 00:00:00
abstract：:Emotional memory consolidation has been associated with rapid eye movement (REM) sleep, and recent evidence suggests that increased electroencephalogram spectral power in the theta (4-8 Hz) frequency range indexes this activity. REM sleep has been implicated in posttraumatic stress disorder (PTSD) as well as in emotio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3857-5
更新日期：2014-05-01 00:00:00
abstract：:The three-dimensional topography of the environment is a potentially important source of orienting information for animals, but little is known about how such features affect either navigational behaviour or the neural representation of place. One component of the neural place representation comprises the hippocampal ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0138-3
更新日期：2006-02-01 00:00:00
abstract：:The foot is a critical interface between the body and supporting surface during walking, but there is no coherent framework on which to model the dynamics of the stance and swing phases. To establish this framework, we studied the rotational and translational dynamics of foot movement in three dimensions with a motion...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0633-1
更新日期：2007-01-01 00:00:00
abstract：:We investigated motor control perspectives of coordinating maintenance of posture and application of grip force when holding an object and being perturbed. Ten subjects stood on the force platform holding an instrumented object in their dominant hand and were exposed to an external perturbation applied to their should...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4717-2
更新日期：2016-11-01 00:00:00
abstract：:We studied the effects of fatigue, induced by a 60-s maximal isometric force production with the index finger, on multi-finger coordination and force production by the other fingers of the hand. Finger forces were measured during single- and multi-finger maximal voluntary force production (MVC) at two sites, the middl...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100698
更新日期：2001-06-01 00:00:00
abstract：:Single unit recordings were carried out in the reticularis thalamic nucleus (RT) and the ventral lateral geniculate body (LGv) of chronically prepared alert cats under sinusoidal vestibular stimulation in the horizontal plane. Optokinetic stimulation was also used. Of the 57 recorded neurons, 12 present vestibular mod...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237394
更新日期：1978-05-12 00:00:00
abstract：:Normal vision overrides perturbed vestibular information for the optimization of performance during goal directed locomotion, suggesting down-regulation of vestibular gain. However, it is not known if the responses to vestibular perturbation are accentuated when vision is impaired. Furthermore, both visual and vestibu...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-006-0593-5
更新日期：2007-01-01 00:00:00
abstract：:Several studies have shown that rapid manual aiming movements from one to the other wing of Müller-Lyer illusion figures are biased in a manner consistent with their influence on perceptual judgments. Two experiments examined the role of extent and position information in Müller-Lyer figures in biasing pointing moveme...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2156-y
更新日期：2005-05-01 00:00:00
abstract：:The aim of this research was to analyse the development of postural reactions to approaching (AOF) and receding (ROF) ground rectilinear optical flows. Optical flows were shaped by a pattern of circular spots of light projected on the ground surface by a texture flow generator. The geometrical structure of the project...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1930-1
更新日期：2004-11-01 00:00:00
abstract：:The vestibular nuclei and the interstitial nucleus of Cajal (INC) have been regarded as key elements of the velocity-to-position integrator for vertical eye movements. This paper reports a class of type II vestibular neurons that receives input from the INC and carries vertical eye movement signals that appear to repr...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1750-8
更新日期：2004-04-01 00:00:00
abstract：:Previous research has demonstrated that negative affect influences attentional processes. Here, we investigate whether pre-experimental negative affect predicts a hypervigilant neural response as indicated by increased event-related potential amplitudes in response to neutral and positive visual stimuli. In our study,...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4544-x
更新日期：2016-06-01 00:00:00
abstract：:Peripheral sensory-motor neuropathy is one of the most frequent side effects of vincristine (VCR) administration, which often limits its usefulness in the treatment of a wide range of neoplastic diseases. The purpose of this work is to study VCR neurotoxicity in experimental animals from clinical, electrophysiological...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0499-2
更新日期：2006-08-01 00:00:00
abstract：:According to the peak and decline model divergent thinking declines at a specific age (in or after middle age). However, if divergent thinking declines steadily in aging still has to be clarified. In order to explore the age-related changes in verbal and visual divergent thinking, in the present study a sample of 159 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4857-4
更新日期：2017-04-01 00:00:00
