Abstract:
:Extracellular Ca2+ activity (aCa) changes were measured with Ca2+-sensitive microelectrodes in the cat cerebral cortex during iontophoretic administration of excitatory and inhibitory aminoacids. Glutamate, aspartate and DL homcysteate usually decreased aCa from a baseline of 1.3 mM to as low as 0.1 mM. The amplitude of the changes was largest at depths between 100 and 300 micrometer beneath the cortical surface. The aCa decreases could be deminished or blocked by Co2+, Mn2+ or La3+ as well as by GABA. These data suggest that large Ca2+ conductances that may be voltage-sensitive are present in apical dendrites of neocortical neurones.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Heinemann U,Pumain Rdoi
10.1007/BF00237788subject
Has Abstractpub_date
1980-01-01 00:00:00pages
247-50issue
3eissn
0014-4819issn
1432-1106journal_volume
40pub_type
杂志文章abstract::Subjects exposed to a rotating environment that perturbs their postural sway show adaptive changes in their voluntary spatially directed postural motion to restore accurate movement paths but do not exhibit any obvious learning during passive stance. We have found, however, that a variable known to characterize the de...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3815-7
更新日期:2014-04-01 00:00:00
abstract::At a descriptive level, prehension movements can be partitioned into three components ensuring, respectively, the transport of the arm to the vicinity of the target, the orientation of the hand according to object tilt, and the grasp itself. Several authors have suggested that this analytic description may be an opera...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228557
更新日期:1996-07-01 00:00:00
abstract::The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005725
更新日期:1997-07-01 00:00:00
abstract::We tested the hypothesis that frontal eye field (FEF) visual activity integrates visual information with a template of a target by examining whether a target that is not present in a search display influences the target selection in FEF. Neural activity was recorded in FEF of macaque monkeys performing visual search f...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1461-1
更新日期:2003-08-01 00:00:00
abstract::When humans pursue motion stimuli composed of alternating constant velocity segments of randomised duration (RD), they nevertheless initiate anticipatory eye deceleration before stimulus direction changes at a pre-programmed time based on averaging prior stimulus timing. We investigated, in both the time and frequency...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-011-2725-9
更新日期:2011-07-01 00:00:00
abstract::Two components of long-term potentiation (LTP) are distinguished with extracellular recording electrodes: a synaptic and an EPSP-Spike (E-S) component. The latter consists of the enhancement produced in the population spike amplitude in excess of that predicted by EPSP potentiation alone. The experiments carried out i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229331
更新日期:1990-01-01 00:00:00
abstract::This study examined the variability in movement end points in a task in which human subjects reached to targets in different locations on a horizontal surface. The primary purpose was to determine whether patterns in the variable errors would reveal the nature and origin of the coordinate system in which the movements...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00241415
更新日期:1994-01-01 00:00:00
abstract::The present study was designed to compare the performance of nine dyslexic boys and nine age- and IQ-matched controls on tasks which presumably tap visual functions dependent on the subcortical magnocellular (M) pathway (flicker sensitivity) and the cortical dorsal stream (stereoacuity, structure-from-motion, visuomot...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231069
更新日期:1995-01-01 00:00:00
abstract::We examined modulation of transmission in short-latency, distal hindlimb cutaneous reflex pathways during fictive locomotion in 19 decerebrate cats. Fictive stepping was produced either by electrical stimulation of the mesencephalic locomotor region (MLR) or by administration of Nialamide and 1-DOPA to acutely spinali...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00250567
更新日期:1989-01-01 00:00:00
abstract::1. The somatic location and axonal projections of inhibitory vestibular nucleus neurons activated by the horizontal semicircular canal nerve (HCN) were studied in anesthetized cats. Cats were anesthetized with ketamine hydrochloride and pentobarbital sodium. 2. Intracellular recordings were obtained from 11 neck exten...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231035
更新日期:1991-01-01 00:00:00
abstract::Six cats were reared with surgically produced squint or atropinisation of one eye during the sensitive period of development. Five cats were reared without an ocular interference but in the same environment as the experimental cats. Four of these normally reared cats provided control data for perikaryal size. When the...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235784
更新日期:1982-01-01 00:00:00
abstract::Transcranial magnetic stimulation (TMS) has been first described 30 years ago, and since then has gained enormous attention by neurologists, psychiatrists, neurosurgeons, clinical neurophysiologists, psychologists, and neuroscientist alike. In the early days, it was primarily used to test integrity of the corticospina...
journal_title:Experimental brain research
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00221-016-4865-4
更新日期:2017-04-01 00:00:00
abstract::In the lateral septal area (LSA), both inhibitory and excitatory dopamine (DA) actions, as well as hypothalamic and midbrain DA efferents, have been described. Some neurons of the hypothalamic and midbrain DA systems contain somatostatin (SOM) or neurotensin (NT), and, in the LSA, the distribution of fibers containing...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229030
更新日期:1993-01-01 00:00:00
abstract::If horizontal saccades or smooth-pursuit eye movements are made with the line-of-sight at different elevations, the three-dimensional (3D) angular rotation axis of the globe tilts by half the vertical eye eccentricity. This phenomenon is named "half-angle rule" and is a consequence of Listing's law. It was recently fo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050943
更新日期:1999-11-01 00:00:00
abstract::The present study attempted to demonstrate that the indicator arm influences end point distribution in contralateral multi-joint proprioceptive tasks and also that intrinsic physical characteristics of multi-joint arms (arm stiffness) may predict the error pattern. For this purpose, we carried out two types of contral...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3196-3
更新日期:2012-10-01 00:00:00
abstract::Intracellular recordings from thalamic neurons receiving cerebellar inputs were performed under urethane anesthesia in the rat. A total of 64 neurons were recorded intracellularly with micropipettes filled with 4% biocytin solution (dissolved in 0.5 M K-acetate), and cerebellar-induced EPSPs (CN-EPSPs), the membrane r...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231841
更新日期:1991-01-01 00:00:00
abstract::The sense of agency is a profoundly important human experience and is strongly linked to volitional action. The importance of this experience is underscored by the fact that many neurological and psychiatric disorders are partially characterized by an abnormal sense of agency (e.g., schizophrenia, anxiety disorders, d...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3372-5
更新日期:2013-09-01 00:00:00
abstract::Using a declarative memory paradigm, the anatomical correlates of spatial location encoding and retrieval in the healthy human brain as reflected by BOLD fMRI were investigated. During encoding, subjects were instructed to view and keep in mind different locations of an object on a platform seen from different viewpoi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0408-8
更新日期:2006-09-01 00:00:00
abstract::The tectofugal pathway in birds has been reported to process primarily information from the contralateral eye. Although this pathway has access to the contralateral hemisphere by various connections, electrophysiological recordings up to now have failed to demonstrate any excitatory influence of visual stimulation in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00271850
更新日期:1988-01-01 00:00:00
abstract::Inter-limb learning transfer (ILT) between the upper-limbs has been well documented, but no corresponding study of the lower limbs has been done. We investigated ILT in the lower limbs of subjects who learned to move a cursor toward targets within 800 ms using ankle movements: plantar/dorsi-flexion and inversion/evers...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1547-x
更新日期:2009-01-01 00:00:00
abstract::The authors determined the effects of changes in task demands on interpersonal and intrapersonal coordination. Participants performed a joint task in which one participant held a stick to which a circle was attached at the top (holding role), while the other held a pointer through the circle without touching its borde...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2653-8
更新日期:2011-06-01 00:00:00
abstract::The arm movement control system often relies on visual feedback to drive motor adaptation and to help specify desired trajectories. Here we studied whether kinematic errors that were indicated with auditory feedback could be used to control reaching in a way comparable with when vision was available. We randomized twe...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3144-2
更新日期:2012-08-01 00:00:00
abstract::In this study, we examined the relationship between a measure of cerebral lateralization--differences in tympanic temperature (T(Ty))--and questionnaire measures of inattentiveness and hyperactivity in both people and dogs. Theories of cerebral lateralization indicate that cerebral asymmetry may improve attentive beha...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3093-9
更新日期:2012-06-01 00:00:00
abstract::We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1237-0
更新日期:2008-03-01 00:00:00
abstract::Sources of primary afferent depolarization (PAD) of skin afferents in the sural (Sur) nerve and of group-II muscle afferents in the posterior biceps and semitendinosus (PBST) nerve were compared at several sites, about 2 mm apart, within the L7-S2 segments in order to define areas of projection of sacral interneurons ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000429
更新日期:2000-08-01 00:00:00
abstract::The mesencephalic dopamine (DA) cell system was examined in mice homozygous and heterozygous for the weaver (wv) gene and in wild-type controls to estimate the extent of cell losses associated with the genetically determined central DA deficiency observed in weaver homozygotes. Animals of the three genotypes (+/+, wv/...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248351
更新日期:1988-01-01 00:00:00
abstract::Owing to the flexibility and redundancy of neuromuscular and skeletal systems, humans can trace the same hand trajectory in space with various arm configurations. However, the joint trajectories of typical unrestrained movements tend to be consistent both within and across subjects. In this paper we propose a method t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0039-5
更新日期:2005-12-01 00:00:00
abstract::To investigate the role of gravitational cues in the learning of a dynamic balancing task, we placed blindfolded subjects in a device programmed with inverted pendulum dynamics about the yaw axis. Subjects used a joystick to try and maintain a stable orientation at the direction of balance during 20 100 s-long trials....
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5216-4
更新日期:2018-05-01 00:00:00
abstract::Adolescence is a transition period that is assumed to be characterized by increased sensitivity to reward. While there is growing research on reward processing in adolescents, investigations into the engagement of brain regions under different reward-related conditions in one sample of healthy adolescents, especially ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3272-8
更新日期:2012-11-01 00:00:00
abstract::The responses of 80 amygdaloid neurons to the four basic taste (sucrose, NaCl, HCl and quinine hydrochloride), thermal (5 degrees C, 20 degrees C and 40 degrees C) and tactile (brushing) stimuli applied to the anterior part of the tongue were recorded in anesthetized rats. About 90% of the taste-sensitive amygdaloid n...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237437
更新日期:1984-01-01 00:00:00