Abstract:
:The present study was designed to compare the performance of nine dyslexic boys and nine age- and IQ-matched controls on tasks which presumably tap visual functions dependent on the subcortical magnocellular (M) pathway (flicker sensitivity) and the cortical dorsal stream (stereoacuity, structure-from-motion, visuomotor control). Increasing evidence suggests that dyslexics experience impairments in M-system functioning. In keeping with previous work supporting this conclusion, dyslexic subjects in the present study were found to have reduced sensitivity to flicker relative to controls. Given that the M system provides the predominant input to the dorsal stream, it was expected that reduced functioning of the M system in dyslexics would result in disruptions of functions related to this cortical visual pathway. Indeed, dyslexic subjects in the present study were found to be less efficient at recognizing structure-from-motion and less accurate at grasping objects precisely. They also showed a mild impairment in stereoacuity. These results, then, lend some support to the hypothesis that dyslexic individuals should show deficiencies on tasks dependent on dorsal stream processing of visual information.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Felmingham KL,Jakobson LSdoi
10.1007/BF00231069subject
Has Abstractpub_date
1995-01-01 00:00:00pages
467-74issue
3eissn
0014-4819issn
1432-1106journal_volume
106pub_type
杂志文章abstract::Neuromagnetic fields from the left cerebral hemisphere of five healthy, right-handed subjects were investigated under three different experimental conditions: (1) electrical stimulation of the right index finger (task S); (2) voluntary movement of the same finger (M); (3) M+S condition, consisting of voluntary movemen...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00230430
更新日期:1996-01-01 00:00:00
abstract::In order to assess the autoinhibitory control of endogenous acetylcholine (ACh) in rat and human neocortex, slices of these tissues were prelabelled with [(3)H]choline, superfused continuously and stimulated electrically using various frequencies in the presence or absence of drugs. The autoinhibitory feedback control...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050858
更新日期:1999-10-01 00:00:00
abstract::Explant cultures of rat spinal cord, brain stem and cerebellum were used to visualize GABAA-receptors by means of immunohistochemistry. For these studies we have incubated the cultures with the monoclonal antibody bd 17 against the beta-subunit of the GABAA/benzodiazepine/chloride channel complex. In spinal cord cultu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228810
更新日期:1990-01-01 00:00:00
abstract::Although postural control requires the integration of different sensory cues, little is known about the role of attentional artifacts on the individual's ability to properly respond to postural challenges. This study investigated the effects of concomitant tasks (cognitive and postural) on the relationship between vis...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4762-x
更新日期:2016-12-01 00:00:00
abstract::The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005725
更新日期:1997-07-01 00:00:00
abstract::The organization of corticocortical connections in the representation of the forepaw in cat primary somatosensory cortex (SI) was studied following injections of various tracers into different cortical cytoarchitectonic areas. Small injections of horseradish peroxidase, wheat germ agglutinin-conjugated HRP, Phaseolus ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227839
更新日期:1992-01-01 00:00:00
abstract::As a consequence of the fragility of various neural structures, preterm infants born at a low gestation and/or birthweight are at an increased risk of developing motor abnormalities. The lack of a reliable means of assessing motor integrity prevents early therapeutic intervention. In this paper, we propose a new metho...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900227
更新日期:2000-04-01 00:00:00
abstract::We used near-infrared spectroscopy to examine dorsolateral prefrontal cortex (DLPFC) activation over time in 10 children with or at-risk-for developmental coordination disorder (DCD) and 11 typically developing children (ages 8-12) during tasks involving executive processing. The groups performed with similar accuracy...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5358-4
更新日期:2018-11-01 00:00:00
abstract::Studies exploring reflexive joint attention report that attention is more powerfully captured by interfering social signals (such as others' gaze or hand orientation) than by non-biological directional cues (such as an arrow). However, what remains unknown is whether these effects are mapped in purely spatial or in bo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1900-8
更新日期:2009-08-01 00:00:00
abstract::Many studies demonstrated a higher accuracy in perception and action when using more than one sense. The maximum-likelihood estimation (MLE) model offers a recent approach on how perceptual information is integrated across different sensory modalities suggesting statistically optimal integration. The purpose of the pr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2099-4
更新日期:2010-04-01 00:00:00
abstract::Transient receptor potential receptors (TRP) on primary afferent neurons respond to noxious and/or thermal stimuli. TRPV1 receptors can be activated by noxious heat, acid, capsaicin and resiniferatoxin, leading to burning pain or itch mediated by discharges in C polymodal and Adelta mechano-heat nociceptors and in cen...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-009-1760-2
更新日期:2009-06-01 00:00:00
abstract::The firing rate of an abducens motoneuron (AbMN) is linearly related to eye position with slope K, above recruitment threshold theta. Within the AbMN population K increases as theta increases. It is possible that these properties depend on the synaptic drives generated by the major premotor inputs to AbMNs, namely pos...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1176-8
更新日期:2002-09-01 00:00:00
abstract::Injections of horseradish peroxidase conjugated with wheat germ agglutinin (WGA-HRP) were made into the cortex of kittens. When cytochrome oxidase histochemistry was performed on sections taken through the injection sites staining of the WGA-HRP deposits occurred, demonstrating that WGA-HRP can cross-react during proc...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238970
更新日期:1985-01-01 00:00:00
abstract::Using near infrared spectroscopy and repetitive transcranial magnetic stimulation (rTMS), we studied interhemispheric interactions between bilateral motor and sensory cortices in humans. RTMS consisted of a triple-pulse burst (50 Hz) repeated every 200 m for 2 s (10 bursts, 30 pulses); one kind of theta burst TMS (TBS...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-0884-5
更新日期:2007-07-01 00:00:00
abstract::Precise left-hand movements take longer than right-hand movements (for right-handers). To quantify how left-hand movements are affected by task difficulty and phase of movement control, we manipulated the difficulty of repetitive speeded aiming movements while participants used the left or right hand. We observed left...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3110-z
更新日期:2012-07-01 00:00:00
abstract::Receptive field (RF) characteristics of cells in primary visual cortex of the mouse (C57B16 strain) were studied by single unit recording. We have studied the functional organization of area 17 along both the radial and tangential dimensions of the cortex. Eighty seven percent of the visual neurons could be classified...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247312
更新日期:1988-01-01 00:00:00
abstract::"Quiet standing" is standing without intended movement. To the naked eye, a person "quiet standing" on a rigid surface of support is stationary. In the laboratory quiet standing is indexed by behavior (at the millimeter scale) of the center of pressure (COP), the point location of the vertical ground reaction force ve...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3696-9
更新日期:2013-12-01 00:00:00
abstract::Performing joint actions often requires precise temporal coordination of individual actions. The present study investigated how people coordinate their actions at discrete points in time when continuous or rhythmic information about others' actions is not available. In particular, we tested the hypothesis that making ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2706-z
更新日期:2011-06-01 00:00:00
abstract::This study examined hippocampal theta power during configural and non-configural tasks in rats. Experiment 1 compared hippocampal theta power during a negative patterning task (A+, B+, AB-) to a configural task and a simple discrimination task (A+, B-) as a non-configural task. The results showed that hippocampal thet...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3359-2
更新日期:2013-03-01 00:00:00
abstract::The factors controlling neurogenesis and differentiation of olfactory receptor cells in adults are poorly understood, although it is often stated that these cells undergo continual turnover after a predetermined lifespan. An interesting model in which to study mechanisms which control olfactory receptor neurogenesis a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247534
更新日期:1988-01-01 00:00:00
abstract::Using different tracer substances the pathways connecting the superior colliculus with the diencephalon were studied in the Madagascan hedgehog tenrec (Echinops telfairi), a nocturnal insectivore with tiny eyes, a small and little differentiated superior colliculus and a visual cortex with no obvious fourth granular l...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228725
更新日期:1996-10-01 00:00:00
abstract::Dementia due to cerebral ischemic lesions is relatively common in the elderly. Since many of these lesions are probably caused by emboli, studying emboli-induced cerebral lesions in rabbits should, hopefully, provide information that is useful when searching for a means of preventing and treating vascular dementia in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050622
更新日期:1999-01-01 00:00:00
abstract::We have investigated the visual responses of 184 single units located in the superficial layers of the optic tectum (OT) of the decerebrate, paralysed pigeon. Visual responses were similar to those reported in non-decerebrate preparations; most units responded best to moving visual stimuli, 18% were directionally sele...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005779
更新日期:1997-10-01 00:00:00
abstract::The brain needs information about the size of the body to control our interactions with the environment. No receptor signals this information directly; the brain must determine body size from multiple sensory inputs and then store this information. This process is poorly understood, but somatosensory information is th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4249-1
更新日期:2015-06-01 00:00:00
abstract::1. The activity of cat semicircular canal and otolith afferents was studied during yaw and roll rotations, respectively, to examine their dynamic behavior. 2. A sinusoidal analysis of the canal afferent activities showed that their dynamic characteristics are similar to those of second order vestibular neurons, except...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239549
更新日期:1978-08-15 00:00:00
abstract::The spatial frequency tuning and the contrast-response function of striate neurons in Siamese cats were investigated with drifting sinusoidal gratings of high contrast, and the results were compared to the data obtained in normally pigmented cats. The optimal spatial frequency of the tuning curves obtained from Siames...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236278
更新日期:1984-01-01 00:00:00
abstract::Prior research has concluded that the correlations of isometric finger forces represent the extent to which the fingers are controlled as a single unit. If this is the case, finger force correlations should be consistent with estimates of the controlled (dynamical) degrees of freedom in finger forces. The present stud...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3280-8
更新日期:2012-12-01 00:00:00
abstract::The effect of claustrum (CL) stimulation on the spontaneous unitary activity of ipsi and contralateral frontal oculomotor neurons, was studied in chloralose-anaesthetized cats. A total of 205 units was bilaterally recorded in the medial oculomotor area, homologous of the primate "frontal eye fields"; 127 neurons were ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230958
更新日期:1991-01-01 00:00:00
abstract::It is an important issue to address the mode of information processing in the somatic motor circuit linking the frontal cortex and the basal ganglia. In the present study, we investigated the extent to which corticostriatal input zones from the primary motor cortex (MI), the supplementary motor area (SMA), and the pre...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050384
更新日期:1998-05-01 00:00:00
abstract::Absolute refractory periods of a subpopulation of corticomedial amygdala (CMA) neurones which project to the medial preoptic/anterior hypothalamic junction (MPH) via the stria terminalis were recorded in the female rat. Previous experiments have shown that this sub-population of CMA neurones is testosterone-sensitive ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236571
更新日期:1981-01-01 00:00:00