Abstract:
:Using a declarative memory paradigm, the anatomical correlates of spatial location encoding and retrieval in the healthy human brain as reflected by BOLD fMRI were investigated. During encoding, subjects were instructed to view and keep in mind different locations of an object on a platform seen from different viewpoints in virtual 3D. In retrieval trials, subjects had to recognize previously learned object locations. Comparing activation patterns associated with encoding and recognition on a voxel-by-voxel basis, we found regions in the precuneus bilaterally activated by both processes. To our knowledge, this is the first study that directly compared human brain activation patterns associated with allocentric encoding and retrieval of spatial locations in virtual 3D. Our results provide further information concerning the role of the precuneus in declarative memory processes, pointing to precuneus involvement in encoding and retrieval of spatial locations.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Frings L,Wagner K,Quiske A,Schwarzwald R,Spreer J,Halsband U,Schulze-Bonhage Adoi
10.1007/s00221-006-0408-8keywords:
subject
Has Abstractpub_date
2006-09-01 00:00:00pages
661-72issue
4eissn
0014-4819issn
1432-1106journal_volume
173pub_type
杂志文章abstract::Dispersed brain cells from 12-14 day old mouse embryos were loaded with the Ca2+-sensitive fluorescent probe, quin2 and shown to have a resting intracellular Ca2+ concentration ([Ca2+]i) of 158 nM (SE +/- 5) in the presence of 1 mM [Ca2+]o. When external [Ca2+] was raised from 0 to 1 mM there was an increase of [Ca2+]...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235975
更新日期:1987-01-01 00:00:00
abstract::Percutaneous electrical stimulation of the motor point of the first dorsal interosseous muscle (FDI) was used to produce a non-painful contraction of the FDI muscle that caused index finger abduction movement but no radiating cutaneous paraesthesias or sharp sensations localized to joints. Pairs of stimuli separated b...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2353-3
更新日期:2005-10-01 00:00:00
abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3090-z
更新日期:2012-06-01 00:00:00
abstract::This study explored the directional specificity of fear of falling (FoF) effects on the stabilizing function of anticipatory postural adjustments (APA). Participants (N = 71) performed a series of lateral leg raises from an elevated surface in three conditions: in the "Control condition", participants stood at the mid...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4471-x
更新日期:2016-03-01 00:00:00
abstract::A database of positron-emission-tomography studies published between January 1993 and November 1996 was created to address several questions regarding the function and connectivity of the human anterior cingulate cortex (ACC). Using this database, we have previously reported on the relationship between behavioural var...
journal_title:Experimental brain research
pub_type: 杂志文章,meta分析
doi:10.1007/s002210000400
更新日期:2000-07-01 00:00:00
abstract::A growing body of evidence suggests that the mode of movement selection is relevant for the readiness potential, namely, internal (or free) selection of movements is associated with increased readiness potential amplitudes compared to predetermined or externally guided selection. It is little acknowledged, however, th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05878-9
更新日期:2020-10-01 00:00:00
abstract::The activity of the rat hindlimb during treadmill stepping was studied in normal adult rats and in rats in which cerebellar development was interfered with by early-postnatal focal X-irradiation. Based on cinematographic and electromyographic data from over 100 step cycles in 15 normal rats, correlations were made bet...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236145
更新日期:1980-01-01 00:00:00
abstract::When humans pursue motion stimuli composed of alternating constant velocity segments of randomised duration (RD), they nevertheless initiate anticipatory eye deceleration before stimulus direction changes at a pre-programmed time based on averaging prior stimulus timing. We investigated, in both the time and frequency...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-011-2725-9
更新日期:2011-07-01 00:00:00
abstract::We used near-infrared spectroscopy to examine dorsolateral prefrontal cortex (DLPFC) activation over time in 10 children with or at-risk-for developmental coordination disorder (DCD) and 11 typically developing children (ages 8-12) during tasks involving executive processing. The groups performed with similar accuracy...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5358-4
更新日期:2018-11-01 00:00:00
abstract::Attention-deficit hyperactivity disorder (ADHD) is a prevalent psychiatric disorder in children that often continues into adulthood. It has been suggested that motor impairments in ADHD are associated with underlying cerebellar pathology. If such is the case, individuals with ADHD should be impaired on motor tasks req...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4190-8
更新日期:2015-04-01 00:00:00
abstract::Vection is the illusion of self-motion in the absence of real physical movement. The aim of the present study was to analyze how multisensory inputs (visual and auditory) contribute to the perception of vection. Participants were seated in a stationary position in front of a large, curved projection display and were e...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3793-9
更新日期:2014-03-01 00:00:00
abstract::Electrical stimulation with repetitive pulses (6/sec) was applied to the internal medullary lamina and produced tonic contraversive turning movements of eyes and head which were associated with recruiting responses in the visual cortex. Optical gratings of a spatial frequency of 0.5 c/deg which alternated with diffuse...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00234015
更新日期:1976-06-18 00:00:00
abstract::Evidence is presented that simple cells in the cat striate cortex (area 17) fail to respond to two dimensional random patterns but respond vigorously to one dimensional patterns with identical power at the preferred orientation of the cell. Further observations suggest that complex cells inhibit simple cells so as to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238391
更新日期:1981-01-01 00:00:00
abstract::Dynamic changes of deficits in canal and otolith vestibulo-ocular reflexes (VORs) to high acceleration, eccentric yaw rotations were investigated in five subjects aged 25-65 years before and at frequent intervals 3-451 days following unilateral vestibular deafferentation (UVD) due to labyrinthectomy or vestibular neur...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0761-7
更新日期:2007-04-01 00:00:00
abstract::The distribution of anterogradely-labeled fibers and retrogradely-labeled cell bodies in the interpeduncular nucleus (IPN) was mapped after injections of wheat-germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) into various structures of the basal forebrain in adult rats. WGA-HRP injections into the medial...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00279657
更新日期:1988-01-01 00:00:00
abstract::The horizontal and vertical components of the positions of both eyes of rhesus monkeys were measured during periods of binocularly stable eye positions (eye pauses) while the animals fixated a small target. Differences between monocular and binocular viewing, as well as effects of target size and background illuminati...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236231
更新日期:1984-01-01 00:00:00
abstract::Saccadic latency is composed of separate sensory and motor processing delays. Therefore, any alteration in the sensory processing should effect the saccadic latency. Because the highest density of benzodiazepine (Bz) binding sites is located in cerebral cortex, sensory processing of stimuli in this cortical area is ex...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2235-8
更新日期:2005-05-01 00:00:00
abstract::To elucidate hemispheric asymmetry in the neurophysiologic mechanisms of global and local information processing, we investigate high-density event-related potentials (ERPs) during divided and selective attention tasks based on detection of hierarchical letters whose spatial frequency is controlled. Twelve healthy mal...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-0948-6
更新日期:2007-08-01 00:00:00
abstract::Gamma band activity participates in sensory perception, problem solving, and memory. This review considers recent evidence showing that cells in the reticular activating system (RAS) exhibit gamma band activity, and describes the intrinsic membrane properties behind such manifestation. Specifically, we discuss how cel...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-013-3794-8
更新日期:2014-05-01 00:00:00
abstract::This study compared the mechanisms of adaptation to stable and unstable dynamics from the perspective of changes in joint mechanics. Subjects were instructed to make point to point movements in force fields generated by a robotic manipulandum which interacted with the arm in either a stable or an unstable manner. Afte...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-003-1443-3
更新日期:2003-07-01 00:00:00
abstract::By measuring the forces applied by each limb supporting the weight of the standing quadruped (cat), before and during elicitation of the placing reaction, it was possible to examine quantitatively and qualitatively the postural events which preceded and accompanied forelimb displacement. The findings are summarized as...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237713
更新日期:1979-10-01 00:00:00
abstract::Grasping using two forelimbs in opposition to one another is evolutionary older than the hand with an opposable thumb (Whishaw and Coles in Behav Brain Res 77:135-148, 1996); yet, the mechanisms for bimanual grasps remain unclear. Similar to unimanual grasping, the localization of matching stable grasp points on an ob...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3643-9
更新日期:2013-10-01 00:00:00
abstract::We investigate the contribution of both hemispheres in a lateralised lexical decision paradigm with emotional and neutral words in healthy volunteers. In a first experiment, high-density EEG analysis using source imaging methods revealed early specific participation of the temporoparietal junctions (TPJ) in both hemis...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-014-3843-y
更新日期:2014-04-01 00:00:00
abstract::The aim of this study was to define the relative contribution of self-generated cutaneous and proprioceptive feedback to haptic shape discrimination by systematically constraining the exploratory strategy. Subjects (n = 23) explored pairs of two-dimensional (2-D) angles (standard angle, 90 degrees; comparison angles, ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0728-8
更新日期:2007-04-01 00:00:00
abstract::Sudden limb displacement evokes a complex sequence of compensatory muscle activity. Following the short-latency reflex and preceding voluntary reactions is an epoch termed the medium-latency reflex (MLR) that could reflect spinal processing of group II muscle afferents. One way to test this possibility is oral ingesti...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5162-6
更新日期:2018-03-01 00:00:00
abstract::Survivin attenuates apoptosis by inhibiting cleavage of some cell proteins by activated caspase-3. We recently discovered strong up-regulation of survivin, primarily in astrocytes and a sub-set of neurons, after traumatic brain injury (TBI) in rats. In this study we characterized co-expression of survivin with activat...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2362-2
更新日期:2005-11-01 00:00:00
abstract::Research in the vestibular field has revealed the existence of a central process, called 'velocity storage', that is activated by both visual and vestibular rotation cues and is modified by gravity, but whose functional relevance during natural motion has often been questioned. In this review, we explore spatial orien...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2568-4
更新日期:2011-05-01 00:00:00
abstract::Quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3H] muscimol (specific GABAA receptor ligand) binding in the male Japanese quail brain. In gonadally intact Japanese quail brains, [3H] muscimol revealed a heterogeneous distribution with high GABAA receptor level...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227088
更新日期:1991-01-01 00:00:00
abstract::The excitability of the corticospinal motor pathways to transcranial magnetic stimulation (TMS) can be differentially modulated by a variety of motor tasks. However, there is emerging evidence that linguistic tasks may alter excitability of the corticospinal motor pathways also. In this study we evaluated the effect o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1648-5
更新日期:2004-01-01 00:00:00
abstract::In many daily situations, balance control is associated with a cognitive activity such as reading or a simple calculation. The objective of this study was to investigate the relationship between these two specific human activities, especially the influence of visual cues and support surface stability on body sway duri...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3913-1
更新日期:2014-07-01 00:00:00