Inhibitory effect of bacterial attachment on candidal growth due to adherence with mannose-sensitive pili.

Abstract:

:A bacterial strain with affinity to Candida albicans was successfully obtained from a natural environment. An uncovered Petri dish containing a suspension of heat-killed C. albicans cells was allowed to stand in a laboratory for several days. Some bacteria which had adhered to the candidal cells were tested for their ability to agglutinate the cells. A bacterial strain, designated later as CAB-1, was found to agglutinate candidal cells through bridging by mannose-sensitive pili. CAB-1 showed similar bacteriological characteristics to those of Citrobacter freundii by ID test. The adherence of CAB-1 to candidal cell was precisely presented by scanning electron microscopy. The inhibitory effect of CAB-1 attachment to candidal cells on the growth of Candida was also preliminarily confirmed.

journal_name

Microbiol Immunol

authors

Seki K,Kobayashi K,Tomiya Y,Sakurada J,Murai M,Usui A,Masuda S

doi

10.1111/j.1348-0421.1998.tb02289.x

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

321-4

issue

4

eissn

0385-5600

issn

1348-0421

journal_volume

42

pub_type

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