Abstract:
:Spontaneous local field potential (LFP) spindle frequencies in cat primary auditory cortex (AI) were estimated from the LFP-trigger autocorrelogram before and after application of sodium salicylate and quinine sulfate. A significant decrease (from 8.7 Hz to 7.6 Hz) was observed. The best modulation frequencies for 251 single units recorded in AI response to periodic click train stimulation also decreased (from 10 Hz to 8.6 Hz) after application of these tinnitus-inducing drugs. The results strongly suggest a central effect of salicylates and quinine in addition to their peripheral ototoxic effects.
journal_name
Hear Resjournal_title
Hearing researchauthors
Kenmochi M,Eggermont JJdoi
10.1016/s0378-5955(97)00137-8subject
Has Abstractpub_date
1997-11-01 00:00:00pages
110-6issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(97)00137-8journal_volume
113pub_type
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