Abstract：
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journal_name
Hear Resjournal_title
Hearing researchauthors
Hudspeth AJ,Martin Pdoi
10.1016/j.heares.2009.12.012subject
Has Abstractpub_date
2010-01-30 00:00:00eissn
0378-5955issn
1878-5891pii
S0378-5955(09)00302-5pub_type
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HEARING RESEARCH文献大全abstract：:The avian auditory papilla provides an interesting object on which to study efferent influences, because whereas a significant population of hair cells in birds is not afferently innervated, all hair cells are efferently innervated (Fischer, 1992, 1994a, b). Previous studies in mammals using contralateral sound to sti...
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doi：10.1016/s0378-5955(99)00126-4
更新日期：1999-12-01 00:00:00
abstract：:Carboplatin preferentially destroys inner hair cells (IHCs) in the chinchilla inner ear, while retaining a near-normal outer hair cell (OHC) population. The present study investigated the functional consequences of IHC loss on the compound action potential (CAP), inferior colliculus potential (ICP) and auditory cortex...
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doi：10.1016/s0378-5955(99)00171-9
更新日期：2000-01-01 00:00:00
abstract：:Hypoxia/ischemia is a major pathogenetic factor in the development of hearing loss. An important transcription factor involved in the signaling and adaptation to hypoxia/ischemia is the hypoxia-inducible factor-1 (HIF-1). To study HIF-1 expression we used an in vitro hypoxia model of explant and dissociated cultures o...
journal_title：Hearing research
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doi：10.1016/s0378-5955(03)00222-3
更新日期：2003-09-01 00:00:00
abstract：:Males and females differ in their subcortical evoked responses to sound. For many evoked response measures, the sex difference is driven by a faster developmental decline of auditory processing in males. Using the frequency-following response (FFR), an evoked potential that reflects predominately midbrain processing o...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.108075
更新日期：2020-12-01 00:00:00
abstract：:The human fetus in utero is hypoxic relative to the neonate due to differences between placental and pulmonary oxygenation. Comparable degrees of hypoxia induced in young and adult animals caused an elevation in hearing threshold of a sensorineural nature. It was hypothesised therefore that the human fetus may also ha...
journal_title：Hearing research
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doi：10.1016/0378-5955(94)90289-5
更新日期：1994-02-01 00:00:00
abstract：:Cochlear implant users with ipsilateral residual hearing combine acoustic and electric hearing in one ear, this is called electric-acoustic stimulation (EAS). In EAS users, masking can be shown for electric probes in the presence of acoustic maskers and vice versa. Masking effects in acoustic hearing are generally att...
journal_title：Hearing research
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doi：10.1016/j.heares.2019.107873
更新日期：2020-02-01 00:00:00
abstract：:The ultrastructure of the spiral ligament was compared in aged and young gerbils to assess the involvement of connective tissues in the lateral wall and particularly the fibrocytes in development of presbyacusis. Pathologic features in fibrocytes of senescent gerbils spanned a wide range reflecting different stages of...
journal_title：Hearing research
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更新日期：2002-10-01 00:00:00
abstract：:The voice is a rich source of information, which the human brain has evolved to decode and interpret. Empirical observations have shown that the human auditory system is especially sensitive to the human voice, and that activity within the voice-sensitive regions of the primary and secondary auditory cortex is modulat...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2015.07.003
更新日期：2015-10-01 00:00:00
abstract：:Severe damage to the organ of Corti leads to degeneration of the spiral ganglion cells (SGCs) which form the auditory nerve. This degeneration starts at the level of synaptic connection of the peripheral processes (PPs) of SGCs with the cochlear hair cells. It is generally thought that from this point SGC degeneration...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.107928
更新日期：2020-05-01 00:00:00
abstract：:We studied hair cell regeneration in the crista ampullaris of the lizard Podarcis sicula both in untreated animals and at early and late time intervals following a single high dose of gentamicin. The study was carried out using the S-phase marker 5-bromo-2'-deoxyuridine. Our ultrastructural and immunofluorescence stud...
journal_title：Hearing research
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doi：10.1016/s0378-5955(03)00040-6
更新日期：2003-04-01 00:00:00
abstract：:Age pigment in the sensory and supporting cells was a prominent characteristic distinguishing old saccules from young. However, the pigment was not distributed uniformly throughout the sensory epithelium but displayed cell-specific patterns of accumulation. The highest cytoplasmic volume density was in the old support...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90038-5
更新日期：1989-01-01 00:00:00
abstract：:Little is known about inner ear development in pigeons. This paper addresses the question of maturation in activity patterns of pigeon auditory nerve fibres, Pigeons that were 1, 2 and 4 weeks and 1, 2, 3 and 4 years old were investigated. Adult-like activity patterns are found 4 weeks post-hatching. Spontaneous activ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(96)00020-2
更新日期：1996-05-01 00:00:00
abstract：:Auditory brainstem responses (ABRs) were evoked in developing wallabies by click and tone burst stimuli delivered by bone conduction and air conduction, at progressive stages of post-natal (pouch) life. ABRs were recorded through the onset of auditory responses (95-110 days), the opening of the external ear canal (125...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00211-6
更新日期：1998-03-01 00:00:00
abstract：:Several studies have reported an increased incidence of auditory dysfunction among HIV/AIDS patients. We used auditory HEI-OC1 cells in cell viability, flow cytometry and caspases 3/7-activation studies to investigate the potential ototoxicity of fourteen HIV antiretroviral agents: Abacavir, AZT, Delavirdine, Didenosi...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.01.005
更新日期：2014-04-01 00:00:00
abstract：:Older adults are often reported in the literature to have greater difficulty than younger adults understanding speech in noise [Helfer and Wilber (1988). J. Acoust. Soc. Am, 859-893]. The poorer performance of older adults has been attributed to a general deterioration of cognitive processing, deterioration of cochlea...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.09.001
更新日期：2014-11-01 00:00:00
abstract：:In previous studies describing the effects of electrically stimulating the olivocochlear bundle, it seems possible that both medial and lateral (MOC and LOC) efferents may have been stimulated. To selectively stimulate MOC efferents, we used an electrode placed at the origin of the MOC efferents in the brainstem (MOC ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(88)90023-8
更新日期：1988-05-01 00:00:00
abstract：:The role of glycine and GABA as inhibitory neurotransmitters in the adult vertebrate nervous system has been well characterized in a variety of model systems, including the auditory, which is particularly well suited for analyzing inhibitory neurotransmission. However, a full understanding of glycinergic and GABAergic...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2011.05.012
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVES:Investigation of bone conduction sound propagation by osseous and non-osseous pathways and their interactions based upon the stimulation site and coupling method of the actuator from a bone conduction hearing aid (BCHA). METHODS:Experiments were conducted on five Thiel embalmed whole head cadaver specimens....
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2019.03.005
更新日期：2019-07-01 00:00:00
abstract：:We report the changes in auditory function that occurred at selected intervals following exposure to an intense pure-tone stimulus. One day old chicks were exposed to a 0.9 kHz tone for 48 h at 120 dB. At 0, 1, 3, 6, 9, 12 and 15 days after exposure, cochlear nucleus sound-evoked potentials were used to assess thresho...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90012-9
更新日期：1989-09-01 00:00:00
abstract：:Spontaneous synaptic activity in afferent fibers innervating hair cells of the lateral line organ was monitored with micropipettes at visually identified locations near the peripheral terminations of the fibers. Spontaneous action potentials as well as spontaneous excitatory post-synaptic potentials (EPSPs) were obser...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90023-i
更新日期：1990-02-01 00:00:00
abstract：:A common problem among the elderly is a difficulty in discriminating speech sounds. One factor that may contribute to this is a deterioration in the ability to process dynamic aspects of speech such as formant transitions. For the aging auditory system, this deterioration in temporal processing speed may be manifest a...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00294-5
更新日期：2001-08-01 00:00:00
abstract：:Spongiform lesions of the gerbil cochlear nucleus are reduced in number and extent by rearing in acoustic isolation compared with rearing while exposed to normal colony low-frequency background noise. This study tested whether rearing under exposure to noise bands of moderate intensity would increase the number and ex...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)90153-8
更新日期：1994-12-01 00:00:00
abstract：:The inferior colliculus (IC) is one nucleus of the central auditory system which displays age-related changes. Inputs to the IC use primarily the amino acid neurotransmitters glutamate and gamma-aminobutryic acid (GABA). Neurochemical and anatomical studies of the Fischer 344 (F344) rat IC have shown decreases in GABA...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(96)00113-x
更新日期：1996-10-01 00:00:00
abstract：:One role of the inferior colliculus (IC) in bats is to create neuronal delay-tuning, which is used for the estimation of target distance in the echolocating bat's auditory system. In this study, we describe response properties of IC delay-tuned neurons of the mustached bat (Pteronotus parnellii) and compare it with th...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2012.02.013
更新日期：2012-04-01 00:00:00
abstract：:Immunolabeling of heregulin, a growth factor that enhances cell proliferation in damaged utricles, and one of its binding receptors, ErbB-2, has been briefly described in the P3 rat cochlea and utricle [Zheng et al. (1999) J. Neurocytol. 28, 901-912]. However, little is known about the distribution of heregulin and it...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(02)00339-8
更新日期：2002-07-01 00:00:00
abstract：:Until recently the responses of the mechanosensitive hair cells of the cochlea have been inferred from their morphology, morphological relationships with other structures in the cochlea, and by indirect electrophysiological measurements. With the advent of techniques for making intracellular recordings from hair cells...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(86)90096-1
更新日期：1986-01-01 00:00:00
abstract：:Left-handed individuals show a 4 ms later Wave Pb in the 45-60 ms latency range of the auditory middle latency response (MLR) than right-handed individuals. Examination of auditory evoked potentials in fifteen right-handed and fifteen left-handed normal hearing adults showed that this difference was not evident in tim...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90187-t
更新日期：1990-04-01 00:00:00
abstract：:The present study examined synaptic potentials of neurons in inferior colliculus (IC) cortex slice and the roles of GABA and glutamate receptors in generating these potentials. Multipolar (82%) and elongated (18%) cells were observed with intracellular biocytin staining. Electrical stimulation of the IC commissure (Co...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00129-x
更新日期：1999-11-01 00:00:00
abstract：:A simple model for the acoustic enhancement of electrically evoked otoacoustic emissions (EEOEs) is presented in this paper. The model is based on the assumption that the enhancement is a result of the local interaction between the electrical current spreading in the scala media and the basilar membrane (BM) response ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00175-1
更新日期：1995-11-01 00:00:00
abstract：:Several electrophysiological and psychophysical studies have shown that the spatial excitation pattern produced by bipolar stimulation of a cochlear implant (CI) can have a dual-peak shape. The perceptual effects of this dual-peak shape were investigated using noise-vocoded CI simulations in which synthesis filters we...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.11.001
更新日期：2015-01-01 00:00:00
