Abstract：
:Single neuron responses to sinusoidal 20 Hz amplitude modulated tone bursts (612.5 ms stimulus-on time at the rate of once per 2.2 s) were studied in the auditory midbrain (torus semicircularis) of the immobilized grass frog (Rana temporaria temporaria). The characteristic frequency stimuli at 30 dB above the minimum threshold included 12 full modulation periods with fixed initial phase. Neurons generally showed good phase-locking to the envelope waveform. 160 of the 186 investigated neurons responded to 80% amplitude modulated stimuli with discharges synchronized to the modulation cycle. For this modulation depth the best phase-locking capability was observed for certain phasic and build-up units. The synchronous response to 10% modulated stimuli was observed in 104 units. Though a few (2 of 29) phasic units were capable of reproducing this modulation with very high fidelity, the general tendency was the increasing of phase-locking capacity for units with a substantial sustained activity. In this condition for 66 units (63% of the units displaying the synchronous response) we observed a significant improvement of phase-locking from the initial to the terminal periods of modulation. This effect could be interpreted as an initial stage of the enhancement of small amplitude changes in the course of the long-term adaptation.
journal_name
Hear Resjournal_title
Hearing researchauthors
Bibikov NG,Nizamov SVdoi
10.1016/s0378-5955(96)00128-1subject
Has Abstractpub_date
1996-11-01 00:00:00pages
23-44issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(96)00128-1journal_volume
101pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:Spongiform lesions of the gerbil cochlear nucleus are reduced in number and extent by rearing in acoustic isolation compared with rearing while exposed to normal colony low-frequency background noise. This study tested whether rearing under exposure to noise bands of moderate intensity would increase the number and ex...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)90153-8
更新日期：1994-12-01 00:00:00
abstract：:Tone-burst-evoked compound action potentials (CAP) from the guinea pig round window (RW) are altered by DC current injection through the RW. The CAP waveform consists of a series of interleaved negative and positive peaks (N(1), P(1), N(2), P(2) etc.) of decreasing amplitude. During positive DC current injection (arou...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/S0378-5955(03)00404-0
更新日期：2004-04-01 00:00:00
abstract：:The concept of perceptual inferences taking place over multiple timescales simultaneously raises questions about how the brain can balance the demands of remaining sensitive to local rarity while utilising more global longer-term predictability to modulate cortical responses. In the present study auditory evoked poten...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.107975
更新日期：2021-01-01 00:00:00
abstract：:Increase in spontaneous neural activity after noise-induced hearing loss has frequently been associated with the phenomenon of tinnitus. Eighteen juvenile and adult cats were exposed for 2 h to a 6 kHz tone with an intensity of 115 dB SPL at the cat's head. Seven non-exposed littermates and seven other normal hearing ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00074-1
更新日期：2003-06-01 00:00:00
abstract：:The auditory system consists of an intricate set of connections interposed between hierarchically arranged nuclei. The ascending pathways carrying sound information from the cochlea to the auditory cortex are, predictably, altered in instances of hearing loss resulting from blockage or damage to peripheral auditory st...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2016.05.018
更新日期：2017-01-01 00:00:00
abstract：:With the purpose of pinpointing the time of onset of electromotility, outer hair cells (OHCs) from apical and basal turns of the cochleae of postnatal gerbils, ranging in age from 6 to 19 days, were isolated and drawn into a glass microchamber. Length changes evoked by transcellular electrical stimulation were detecte...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)90046-9
更新日期：1994-07-01 00:00:00
abstract：:The purpose of this study was to evaluate whether there were significant differences in audibility of American English vowels in noise produced by non-native and native speakers. Detection thresholds for 12 English vowels with equalized durations of 170 ms produced by 10 English-, Chinese- and Korean-native speakers w...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2011.08.013
更新日期：2011-12-01 00:00:00
abstract：:Mitochondrial DNA (mtDNA) mutations/deletions are considered to be associated with the development of age-related hearing loss (AHL). We assessed the role of accumulation of mtDNA mutations in the development of AHL using Polg(D257A) knock-in mouse, which exhibited increased spontaneous mtDNA mutation rates during agi...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2006.06.004
更新日期：2007-04-01 00:00:00
abstract：:To create experimental lesions localized to the low frequency region of the organ of Corti, a cryoprobe was applied to the apical area of 37 cochleas from 26 adult chinchillas. Twenty cochleas were exposed to single applications of a cryoprobe for 2.5, 3.0 and 3.5 min; 17 cochleas were exposed to two applications of 1...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90065-7
更新日期：1987-01-01 00:00:00
abstract：:This study examined the effect of monaural middle ear destruction on postnatal development of auditory response properties of inferior collicular (IC) neurons of the laboratory mouse, Mus musculus. Monaural middle ear destruction was performed on juvenile and adult mice and the auditory response properties of neurons ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00304-5
更新日期：2001-09-01 00:00:00
abstract：:During the simultaneous monaural presentation of two primary tones, distortion products can be measured acoustically in the ear canal (DPOAEs) and electrically as auditory evoked potentials (DPAEPs). The purpose of this investigation was to elucidate the sources of nonlinearity within the human auditory system respons...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.04.005
更新日期：2004-07-01 00:00:00
abstract：:Nitric oxide (NO) not only has normal physiological roles like vasodilation and neurotransmission in the living organism, it could also have possible neurodestructive effects under certain pathological conditions. The present study aimed to determine whether direct exposure of guinea pig cochlea to a NO donor like sod...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00159-7
更新日期：1997-12-01 00:00:00
abstract：:Cochlear implant recipients show improved speech perception and music appreciation when residual acoustic hearing is combined with the cochlear implant. However, up to one third of patients lose their pre-operative residual hearing weeks to months after implantation, for reasons that are not well understood. This stud...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2015.12.012
更新日期：2016-03-01 00:00:00
abstract：:This report describes a study that took advantage of the unique reactivity of the patas monkey (Erythrocebus patas) to dihydrostreptomycin-sulfate (DHSM) to investigate the effects of selective outer hair cell (OHC) lesions on psychophysical tuning curves (PTC). Four patas monkeys were trained using operant reinforcem...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90161-4
更新日期：1987-01-01 00:00:00
abstract：:Laser Doppler vibrometry was used to measure the sound-induced tympanic membrane (TM) velocity, assessed near the umbo, in 56 normal hearing human subjects at nine sound frequencies. A second series of measurements was made in 47 subjects with sensorineural hearing loss (SNHL). Each set of measurements has features in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00332-0
更新日期：2004-01-01 00:00:00
abstract：:The laminar distribution and reciprocity of commissural axon terminals and cells of origin in cat primary auditory cortex (AI) were studied after injections of tritiated proline combined with horseradish peroxidase in the middle ectosylvian gyrus. Terminal fields were found in every cortical layer in the contralateral...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(86)90110-3
更新日期：1986-01-01 00:00:00
abstract：:The highest spectral ripple density at which the discrimination of ripple glide direction was possible (STRtdir task) was assessed for one-octave wide (narrowband) stimuli with center frequencies of 500, 1000, 2000, and 4000 Hz and for a broadband stimulus. A pink noise lowpass filtered at the lower edge frequency of ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.107910
更新日期：2020-04-01 00:00:00
abstract：:The vestibular organs of young and very old C57BL/6NNia (B6) mice were compared by light and electron microscopy. Hair cell density decreased an average of 14% in the utricle, 19% in the saccule and posterior crista, 23% in the horizontal crista, and 24% in the anterior crista. Hair cell size remained the same through...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90156-0
更新日期：1987-01-01 00:00:00
abstract：:Otoacoustic emissions (OAEs) differ between the sexes in humans, rhesus and marmoset monkeys, and sheep. OAEs also are different in a number of special populations of humans. Those basic findings are reviewed and discussed in the context of possible prenatal-androgen effects on the auditory system. A parsimonious expl...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2009.01.002
更新日期：2009-06-01 00:00:00
abstract：:Subjective tinnitus may be defined as the perceptual correlate of altered spontaneous neural activity occurring in the absence of an externally evoking auditory stimulus. Tinnitus can be caused or exacerbated by one or more of five forms of stress. We propose and provide evidence supporting a model that explains, but ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/s0378-5955(00)00235-5
更新日期：2001-02-01 00:00:00
abstract：:This study was performed to elucidate the contribution of the stapedial artery (SA)--which has been considered to be independent of the vertebrobasilar system--to blood flow in the ear by observing ear blood flow in Sprague-Dawley rats. A laser-Doppler (LD) probe was positioned on the bony wall of the cochlear basal t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00310-1
更新日期：2003-12-01 00:00:00
abstract：:Activation of heat shock factors (Hsfs) is one of the potential mechanisms for regulating the transcription of the heat shock proteins (Hsps) and certain other stress-responsive genes. Reverse transcription polymerase chain reaction (RT-PCR), Western blot and immunocytochemistry were used to examine the expression and...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(02)00607-x
更新日期：2002-11-01 00:00:00
abstract：:For the purpose of creating a finite element model of the middle ear, the ossicles can be modelled as rigid bodies or as linear elastic materials. The general elasticity parameters used are usually measured on larger bones like the femur. In order to obtain a highly realistic model, the actual elastic modulus (Young's...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2009.10.001
更新日期：2010-05-01 00:00:00
abstract：:Genetically manipulated mice have gained a prominent role in in vivo research on development and function of the auditory system. A prerequisite for the interpretation of normal and abnormal structural and functional features of the inner ear is the exact knowledge of the cochlear place-frequency map. Using a stereota...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.08.011
更新日期：2005-04-01 00:00:00
abstract：:Extracellular adenosine has been suggested as a modulator of cochlear function. To date the release of adenosine into the extracellular spaces of the cochlea has not been demonstrated. Therefore, experiments were designed to examine whether adenosine release into perilymph could be detected in response to depolarizati...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.03.009
更新日期：2005-07-01 00:00:00
abstract：:In mammals, the cochlear sensory epithelium becomes quiescent early during development. After the first postnatal week, there is no cell replacement or proliferation, and severe damage leads to permanent deafness. Supporting cells' trans-differentiation has been suggested as a way to regenerate cochlear hair cells aft...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.12.002
更新日期：2019-03-01 00:00:00
abstract：:Intracellular recordings were made from both inner and outer hair cells (IHC, OHC) in the basal coil of the guinea pig cochlea before, during and after the animal was exposed to loud, pure tones. Following multiple loud tones both types of sensory cells demonstrate a culmulative decrease in their voltage responses to ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(88)90040-8
更新日期：1988-09-01 00:00:00
abstract：:The mastoid air cell system has traditionally been considered to have a passive role in gas exchange and pressure regulation of the middle ear possibly with some acoustic function. However, more evidence has focused on the mucosa of the mastoid, which may play a more active role in regulation of middle ear pressure. I...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2013.03.002
更新日期：2013-07-01 00:00:00
abstract：:Although most birds encounter large pressure variations during flight, motion of the middle ear components as a result of changing ambient pressure are not well known or described. In the present study, motion of the columella footplate and tympanic membrane (extrastapedius) in domestic chickens (Gallus gallus domesti...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.05.012
更新日期：2018-08-01 00:00:00
abstract：:The molecular composition and three-dimensional organization of the extracellular matrix (ECM) was studied by immunofluorescent microscopy, transmission and scanning electron microscopy in three connective tissue structures of the cochlea: the spiral limbus, basilar membrane and spiral ligament. Type II collagen, fibr...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00219-6
更新日期：1999-03-01 00:00:00
