Abstract：
:Guinea pigs were exposed to 120 dB white noise for 30 min and evidenced a four-fold elevation in plasma concentration of the potent vasoconstricting hormone angiotensin II (AII). Anesthetized animals received intra-arterial injections of AII at doses that approximated the endogenous levels measured following noise exposure. A marked decrease in skin blood flow was observed with a concomitant increase in cochlear blood flow as measured by laser Doppler flowmeters. Increased cochlear blood flow appeared to be secondary to the increases in systemic blood pressure induced by AII. These findings suggest that cochlear blood flow may increase during periods of intense noise exposure.
journal_name
Hear Resjournal_title
Hearing researchauthors
Wright JW,Dengerink HA,Miller JM,Goodwin PCdoi
10.1016/0378-5955(85)90128-5subject
Has Abstractpub_date
1985-01-01 00:00:00pages
41-6issue
1eissn
0378-5955issn
1878-5891pii
0378-5955(85)90128-5journal_volume
17pub_type
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