Abstract：
:This study is the continuation of the functional probing of the auditory periphery in the normal and jaundiced rat. Threshold tuning curves from normal rat auditory nerve fibers were comparable to those reported in other mammals. Life-long unconjugated hyperbilirubinemia does not appear to have a widespread, demonstrable effect on cochlear frequency selectivity and sensitivity as measured by the shapes of FTCs of single auditory nerve fibers. Most fibers from the jj Gunn rats had threshold tuning curves as sharp as those from control animals (Jj Gunn and Long-Evans). Any difference seems to lie in a greater threshold variability, particularly for the high-SR fibers, for the Gunn rat strain. Two-tone rate suppression, particularly above CF, was detected in most fibers from the three groups of rats. The optimal suppression frequency (SF) as a function of CF displayed the same progression. Suppression thresholds at any given CF were generally higher for high-SR fibers than for low-SR fibers for all three groups of animals.
journal_name
Hear Resjournal_title
Hearing researchauthors
el Barbary Adoi
10.1016/0378-5955(91)90139-zsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
91-104issue
1eissn
0378-5955issn
1878-5891pii
0378-5955(91)90139-Zjournal_volume
54pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:The dorsal cochlear nucleus (DCN) has been shown to project to a region of the nucleus reticularis pontis caudalis (PnC) critical for the evocation of startle in rats, suggesting a possible modulatory influence of the DCN on startle. This study examined the involvement of the DCN in the acoustic startle reflex and var...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00040-9
更新日期：1998-05-01 00:00:00
abstract：:Genetically manipulated mice have gained a prominent role in in vivo research on development and function of the auditory system. A prerequisite for the interpretation of normal and abnormal structural and functional features of the inner ear is the exact knowledge of the cochlear place-frequency map. Using a stereota...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.08.011
更新日期：2005-04-01 00:00:00
abstract：:The auditory brainstem response (ABR) is an acoustically evoked potential commonly used to determine hearing sensitivity in laboratory animals. Both isoflurane and ketamine/xylazine anesthesia are commonly used to immobilize animals during ABR procedures. Hearing threshold determination is often the primary interest. ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2012.04.005
更新日期：2012-05-01 00:00:00
abstract：:This study explored the effects on speech intelligibility of across-formant differences in fundamental frequency (ΔF0) and F0 contour. Sentence-length speech analogues were presented dichotically (left = F1+F3; right = F2), either alone or-because competition usually reveals grouping cues most clearly-accompanied in t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.10.026
更新日期：2017-02-01 00:00:00
abstract：:We recorded auditory evoked magnetic fields from 8 patients with unilateral, idiopathic, sudden, sensorineural hearing loss and from 8 healthy controls, using a 122-channel whole-scalp neuromagnetometer. The stimuli were 50-ms l-kHz tone bursts, delivered to the healthy ear at interstimulus intervals (ISIs) of 1, 2, 4...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00086-j
更新日期：1995-07-01 00:00:00
abstract：:In order to investigate the localization and the type(s) of excitatory amino acid receptors in the frog vestibular system, the exogenous amino acid agonists Quisqualic acid, Kainic acid and N-methyl-D-aspartic acid were tested on the sensory organ of semicircular canals. Intracellular recordings of the resting dischar...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90006-b
更新日期：1990-07-01 00:00:00
abstract：:Sodium salicylate (SS) can penetrate the blood-brain barrier to target neurons in the central auditory system. Understanding how SS alters functional behaviors of different types of central auditory neurons will provide insights into the neural mechanisms of SS-induced tinnitus. Here, we report the differential effect...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2009.03.007
更新日期：2009-07-01 00:00:00
abstract：:The f2-f1 distortion product otoacoustic emission (DPOAE) can be observed to undergo gradual alterations in amplitude during continuous ipsilateral stimulation with primary tones. In the present experiments, we characterized the dependence of these amplitude alterations on several stimulus variables (intensity, durati...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00041-2
更新日期：1995-05-01 00:00:00
abstract：:Temporary threshold shifts (TTS), of the cochlear action potential in the guinea pig, caused by a high frequency exposure tone could be reduced by a prior exposure at the same frequency but lower intensity. The TTS caused by the initial, low intensity exposure tone was allowed to recover to levels where the thresholds...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(83)90105-3
更新日期：1983-11-01 00:00:00
abstract：:Listening to speech in noise can be effortful but when motivated people seem to be more persevering. Previous research showed effects of monetary reward on autonomic responses like cardiovascular reactivity and pupil dilation while participants processed auditory information. The current study examined the effects of ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.07.011
更新日期：2018-09-01 00:00:00
abstract：:In cases of sudden, reversible hearing loss where perilymphatic fistulas are thought to be the cause, a multitude of causes have been postulated. These include perilymphatic pressure changes, Simmons' double-break theory, perilymphatic hemorrhage, pneumolabyrinth, and others. This study was proposed to explore the rol...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(02)00389-1
更新日期：2002-05-01 00:00:00
abstract：:Measurements of the responses to tones and clicks were made from single primary auditory fibres of the caiman. The distribution of the amplitude and phase of the fundamental component of the response rate modulation over the best frequencies of the fibres is comparable to that reported in the cat, despite the fact tha...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(86)90052-3
更新日期：1986-01-01 00:00:00
abstract：:The olivocochlear bundle was sectioned at the floor of the fourth ventricle in a series of cats. From three to thirty weeks post-operatively, recordings were made from single auditory-nerve fibers. Tuning curves, spontaneous discharge rates, and rate-level functions for tones at the characteristic frequency were measu...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90105-x
更新日期：1990-11-01 00:00:00
abstract：:We review event-related slow firing changes in the auditory cortex and related brain structures. Two types of changes can be distinguished, namely increases and decreases of firing, lasting in the order of seconds. Triggering events can be auditory stimuli, reinforcers, and behavioral responses. Slow firing changes te...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2010.05.003
更新日期：2011-01-01 00:00:00
abstract：:Membrane-bound guanylyl cyclases (GCs) are peptide hormone receptors whereas the cytosolic isoforms are receptors for nitric oxide. In the inner ear, the membrane-bound GCs may be involved in the regulation of fluid homeostasis and the cytosolic forms possibly play a role in signal processing and regulation of local b...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00176-2
更新日期：1999-01-01 00:00:00
abstract：:The purpose of this study was to investigate horizontal plane localization and interaural time difference (ITD) thresholds for 14 adult cochlear implant recipients with hearing preservation in the implanted ear. Localization to broadband noise was assessed in an anechoic chamber with a 33-loudspeaker array extending f...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.02.007
更新日期：2014-06-01 00:00:00
abstract：:Emerging evidence suggests that cochlear synaptopathy is a common feature of sensorineural hearing loss, but it is not known to what extent electrophysiological metrics targeting synaptopathy in animals can be applied to people, such as those with impaired audiograms. This study investigates the applicability of subco...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：:Spatial hearing skills are essential for children as they grow, learn and play. These skills provide critical cues for determining the locations of sources in the environment, and enable segregation of important sounds, such as speech, from background maskers or interferers. Spatial hearing depends on availability of ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2016.01.003
更新日期：2016-08-01 00:00:00
abstract：:Nitric oxide (NO) is a messenger molecule that mediates several physiological functions and pathological processes. Sodium nitroprusside (SNP), a potent vasodilator, when given clinically as an anti-hypertension agent, exerts its function by releasing NO. It was reported recently that SNP causes a loss of auditory ner...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(96)00076-7
更新日期：1996-09-15 00:00:00
abstract：:The directional dependence of sound pressure transformation of head and pinna has been measured in the phyllostomid bat Phyllostomus discolor for the frontal hemisphere using a maximum length sequence method. The azimuthal position of the axis of highest pinna gain came closer to the midsagital plane with increasing f...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00164-3
更新日期：2003-07-01 00:00:00
abstract：:Despite advances in technology, the ability to perceive music remains limited for many cochlear implant users. This paper reviews the technological, biological, and acoustical constraints that make music an especially challenging stimulus for cochlear implant users, while highlighting recent research efforts to overco...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2013.04.009
更新日期：2014-02-01 00:00:00
abstract：:A critical issue in large-scale gene expression analysis is the impact of sexually dimorphic genes, which may confound the results when sampling across sexes. Here, we assessed, for the first time, sex differences at the transcriptome level in the auditory brainstem. To this end, microarray experiments covering the wh...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2008.08.008
更新日期：2008-11-01 00:00:00
abstract：:We have studied the noradrenergic and serotonergic changes induced by white noise stimulation at 70, 90 or 110 dB SPL for 45 min, in cochlear nuclei, inferior colliculus (IC), primary auditory cortex (PAC) and as a comparison in locus coeruleus (LC) and raphe dorsalis using HPLC. Both noradrenergic and serotonergic pa...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(98)00031-8
更新日期：1998-04-01 00:00:00
abstract：:The cytosolic pH (pHi) of transitional cells from the ampulla of the gerbil was measured micro-fluorometrically with the pH-sensitive dye 2',7'-bicarboxyethyl-5(6)-carboxyfluorescein (BCECF) to assess the possible contribution of a Na+/H+ exchanger to the regulation of pHi. All experiments were conducted in virtually ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(93)90098-l
更新日期：1993-09-01 00:00:00
abstract：:Recently, ocular vestibular evoked myogenic potentials (oVEMPs) have been described and added to the neuro-otologic test battery as a new measure for the vestibulo-ocular reflex. oVEMPs represent extraocular muscle activity in response to otolith stimulation e.g. by air-conducted sound or bone-conducted vibration. In ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2012.10.008
更新日期：2012-12-01 00:00:00
abstract：:We have injected by iontophoresis 4-amino-pyridine, a K+ channel blocker and BAPTA, (a Ca++ chelator), into scala media of the first three turns of the guinea pig cochlea. We measured the reduction in outer hair cell (OHC) receptor current, as indicated by cochlear microphonic measured in scala media evoked by a 207 H...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.05.016
更新日期：2006-01-01 00:00:00
abstract：:Healthy guinea pigs were exposed to broad band noise at levels between 95 and 115 dBA for 7 days. A significant decrease of the sound-induced cochlear responses, together with a substantial increase of the endocochlear potential, was observed in guinea pigs exposed to noise at 105 or 115 dBA. Microsamples of the endol...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(79)90004-2
更新日期：1979-12-01 00:00:00
abstract：:Cochlear implantation (CI), which directly stimulates the cochlear nerves, is the most effective and widely used medical intervention for patients with severe to profound sensorineural hearing loss. The etiology of the hearing loss is speculated to have a major influence of CI outcomes, particularly in cases resulting...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2017.02.017
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVES:Investigation of bone conduction sound propagation by osseous and non-osseous pathways and their interactions based upon the stimulation site and coupling method of the actuator from a bone conduction hearing aid (BCHA). METHODS:Experiments were conducted on five Thiel embalmed whole head cadaver specimens....
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2019.03.005
更新日期：2019-07-01 00:00:00
abstract：:The effects of hyperosmolar substances on the ultrastructure of the endolymphatic sac were studied in mice. Fifteen minutes after intravenous injection of urea or glycerol, subcellular changes in the endolymphatic sac were observed. These consisted of the occurrence of abundant cytoplasmic granules with a floccular or...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(88)90045-7
更新日期：1988-09-01 00:00:00
