Human intestinal folate transport: cloning, expression, and distribution of complementary RNA.

abstract：:A patient with the acquired immunodeficiency syndrome (AIDS) with a cytomegalovirus (CMV) infection localized in the area of an ileal Kaposi sarcoma resulting in perforation is described. Because only one case of such an association of Kaposi sarcoma with CMV leading to perforation has been reported, the presence and ...

journal_title：Gastroenterology

authors： Genta RM,Bleyzer I,Cate TR,Tandon AK,Yoffe B

更新日期：1993-06-01 00:00:00

abstract：:Endoscopic submucosal dissection was developed in Japan, early in this century, to provide a minimally invasive yet curative treatment for the large numbers of patients with early gastric cancer identified by the national screening program. Previously, the majority of these patients were treated surgically at substant...

journal_title：Gastroenterology

authors： Bourke MJ,Neuhaus H,Bergman JJ

更新日期：2018-05-01 00:00:00

abstract：:Intracellular microelectrodes were used to evaluate electrical properties of the cell membranes in Necturus antral mucosa during exposure to luminal acid alone (pH 4) or to 5 mmol/L aspirin [acetylsalicylic acid (ASA)] in the presence of luminal acid. When nutrient solutions were buffered by HCO3- (pH 7.3), ASA modera...

journal_title：Gastroenterology

authors： Soybel DI,Davis MB,West AB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND & AIMS:The molecular features of colorectal tumors differ with their anatomic location. Colorectal tumors are usually classified as proximal or distal. We collected data from 3 cohorts to identify demographic, clinical, anthropometric, lifestyle, and dietary risk factors for colorectal cancer (CRC) at 7 anat...

journal_title：Gastroenterology

authors： Wang L,Lo CH,He X,Hang D,Wang M,Wu K,Chan AT,Ogino S,Giovannucci EL,Song M

更新日期：2020-07-01 00:00:00

abstract：:Some of the most common symptoms of the inflammatory bowel diseases (IBD, which include ulcerative colitis and Crohn's disease) are abdominal pain, diarrhea, and weight loss. It is therefore not surprising that clinicians and patients have wondered whether dietary patterns influence the onset or course of IBD. The que...

journal_title：Gastroenterology

authors： Lee D,Albenberg L,Compher C,Baldassano R,Piccoli D,Lewis JD,Wu GD

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:It is generally believed that M cells do not modify the antigens they transport from the intestinal lumen to underlying immunocompetent cells because it has been reported that M cells contain few elements of the lysosomal system. METHODS:We used specific cytochemical and immunocytochemical probes to examine...

journal_title：Gastroenterology

authors： Allan CH,Mendrick DL,Trier JS

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND & AIMS:Recent studies indicate that kringle 1-5 has a potent and specific antiangiogenic activity. Here, we investigated the antitumor effect of kringle 1-5 gene transfer on hepatocellular carcinoma in mice. METHODS:The inhibitory effect of kringle 1-5 protein on proliferation of bovine capillary endothelia...

journal_title：Gastroenterology

authors： Torimura T,Ueno T,Kin M,Taniguchi E,Nakamura T,Inoue K,Sakata R,Hashimoto O,Sakamoto M,Ohira H,Kumashiro R,Sata M,Yano H,Kojiro M,Veitonmaki N,Cao Y

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND & AIMS:Cellular and molecular mechanisms of esophageal ulcer healing remain unexplored. We studied the sequential cellular events and the expression of keratinocyte growth factor (KGF) and its receptor (KGF-R) during the healing of experimental esophageal ulcers. METHODS:Esophageal ulcers were produced in r...

journal_title：Gastroenterology

authors： Baatar D,Kawanaka H,Szabo IL,Pai R,Jones MK,Kitano S,Tarnawski AS

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND & AIMS:Infliximab is effective in closing fistulas in patients with Crohn's disease. We examined the effect of infliximab maintenance treatment on hospitalizations, surgeries, and procedures in patients with fistulizing Crohn's disease enrolled in the ACCENT II study. METHODS:After 5 mg/kg infliximab at wee...

journal_title：Gastroenterology

authors： Lichtenstein GR,Yan S,Bala M,Blank M,Sands BE

更新日期：2005-04-01 00:00:00

abstract：:The possible involvement of tumor necrosis factor-alpha in the pathogenesis of an experimentally induced hepatitis was investigated. Balb/c mice were primed with Propionibacterium acnes to induce the infiltration of mononuclear cells into the liver. Immunohistochemical study showed that most of the accumulated mononuc...

journal_title：Gastroenterology

authors： Nagakawa J,Hishinuma I,Hirota K,Miyamoto K,Yamanaka T,Tsukidate K,Katayama K,Yamatsu I

更新日期：1990-09-01 00:00:00

abstract：:We tested the hypothesis that the hepatic siderosis that characterizes sporadic porphyria cutanea tarda is due to the presence of HLA-linked hemochromatosis alleles. We studied 21 probands with sporadic porphyria cutanea tarda and 135 of their relatives by determining HLA haplotypes and measuring transferrin saturatio...

journal_title：Gastroenterology

authors： Edwards CQ,Griffen LM,Goldgar DE,Skolnick MH,Kushner JP

更新日期：1989-10-01 00:00:00

abstract：:A new experimental model, the isolated perfused antrectomized pig stomach with intact vagal innervation, was shown to produce pepsinogen and gastric acid upon electrical stimulation of the vagus nerves and by intravascular administration of carbachol (from a basal value of 111 +/- 24 units of pepsin per minute and 0.0...

journal_title：Gastroenterology

authors： Skak-Nielsen T,Holst JJ,Nielsen OV

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND & AIMS:Coffee is one of the most widely consumed beverages worldwide. Epidemiologic data indicate that coffee consumption protects against the progression of chronic liver disease and development of hepatocellular carcinoma and diabetes, but the mechanisms are not clear. UDP glucuronosyltransferases (UGT1A) ...

journal_title：Gastroenterology

authors： Kalthoff S,Ehmer U,Freiberg N,Manns MP,Strassburg CP

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND & AIMS:We have reported that contrast echocardiography is a sensitive screening test for the hepatopulmonary syndrome (HPS). However, contrast echocardiography lacks specificity because many cirrhotic patients have positive study results with normal arterial blood gases and therefore do not fulfill criteria ...

journal_title：Gastroenterology

authors： Abrams GA,Nanda NC,Dubovsky EV,Krowka MJ,Fallon MB

更新日期：1998-02-01 00:00:00

abstract：:Intraarterial vasopressin has been reported to be effective in the treatment of massive upper gastrointestinal hemorrhage. A prospective, controlled clinical trial comparing conventional treatment with conventional therapy plus intraarterial vasopressin was undertaken. Sixty episodes of upper gastrointestinal hemorrha...

journal_title：Gastroenterology

authors： Conn HO,Ramsby GR,Storer EH,Mutchnick MG,Joshi PH,Phillips MM,Cohen GA,Fields GN,Petroski D

更新日期：1975-02-01 00:00:00

abstract：:If increased gamma-aminobutyric acid (GABA)-mediated neurotransmission contributes to the mediation of hepatic encephalopathy, it may be possible to induce ameliorations of the syndrome by pharmacologically antagonizing a component of the GABA/benzodiazepine receptor complex. To test this possibility we administered t...

journal_title：Gastroenterology

authors： Bansky G,Meier PJ,Riederer E,Walser H,Ziegler WH,Schmid M

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND & AIMS:The activation of Wnt/beta-catenin signaling causes the development of gastric and colon cancers. Sox17 represses Wnt/beta-catenin signaling and is down-regulated in colon cancer. This study was designed to elucidate the role of Sox17 during the course of gastrointestinal tumorigenesis. METHODS:Sox17...

journal_title：Gastroenterology

authors： Du YC,Oshima H,Oguma K,Kitamura T,Itadani H,Fujimura T,Piao YS,Yoshimoto T,Minamoto T,Kotani H,Taketo MM,Oshima M

更新日期：2009-10-01 00:00:00

abstract：:We examined whether patients with irritable bowel syndrome have increased airway responsiveness by measuring forced expiratory volumes in 1 second (FEV1) after inhalation of increasing concentrations of methacholine. Responses obtained in 11 IBS patients were compared with those obtained in 11 normal subjects and in 1...

journal_title：Gastroenterology

authors： White AM,Stevens WH,Upton AR,O'Byrne PM,Collins SM

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND & AIMS:Recombinant human interleukin 11 (rhIL-11) is a cytokine with thrombocytopoietic activity and anti-inflammatory and mucosal protective effects. The objectives of this study were to investigate the safety and tolerability of rhIL-11 in patients with Crohn's disease and to explore the effects of dose an...

journal_title：Gastroenterology

authors： Sands BE,Bank S,Sninsky CA,Robinson M,Katz S,Singleton JW,Miner PB,Safdi MA,Galandiuk S,Hanauer SB,Varilek GW,Buchman AL,Rodgers VD,Salzberg B,Cai B,Loewy J,DeBruin MF,Rogge H,Shapiro M,Schwertschlag US

更新日期：1999-07-01 00:00:00

abstract：:A rapid immunohistochemical method using 5'-bromo-2'-deoxyuridine (BrdU), a thymidine analog, for labeling proliferating epithelial cells was modified and tested for accuracy against standard tritiated thymidine autoradiography (3H-TdR) in rat esophagus, stomach, duodenum, and colon. Either BrdU or 3H-thymidine or bot...

journal_title：Gastroenterology

authors： Lacy ER,Kuwayama H,Cowart KS,King JS,Deutz AH,Sistrunk S

更新日期：1991-01-01 00:00:00

abstract：:2-Camphanone is under clinical evaluation for alleviation of hemorrhoidal bleeding and inflammation. Reduced portal venous blood flow may distend, whereas improved portal venous blood flow may alleviate, hemorrhoidal vein distention. The effects of 2-camphanone on canine portal venous blood flow were investigated usin...

journal_title：Gastroenterology

authors： Xie JM,Greenberg SS,Longenecker G

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND & AIMS:Host genetic factors are likely to contribute to the variable course of hepatic fibrosis in response to chronic liver injury. Similarly, the fibrotic response differs among inbred mouse strains after challenge with CCl(4). Our aim was to identify unknown susceptibility loci for hepatic fibrosis in a c...

journal_title：Gastroenterology

authors： Hillebrandt S,Goos C,Matern S,Lammert F

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND & AIMS:The physiologic function of the efflux transporter Multidrug Resistance Protein 3 (MRP3) remains poorly defined. In vitro, MRP3 transports several glucuronidated compounds, but the compounds transported under physiologic conditions are unknown. Knowledge of the compounds transported by MRP3 in vivo wo...

journal_title：Gastroenterology

authors： van de Wetering K,Feddema W,Helms JB,Brouwers JF,Borst P

更新日期：2009-11-01 00:00:00

abstract：:Disseminated cytomegalovirus infection occurs predominantly in immunocompromised hosts. Involvement of the gastrointestinal tract in the acquired immunodeficiency syndrome is frequent, but to our knowledge there is only one report of involvement of the appendix. In this study, a patient with a history of the acquired ...

journal_title：Gastroenterology

authors： Valerdiz-Casasola S,Pardo-Mindan FJ

更新日期：1991-07-01 00:00:00

abstract：:There are conflicting reports on the influence of cigarette smoking on healing in patients with duodenal ulcer; some studies show an adverse effect on healing rate and others no effect. This study reports the influence of smoking on short-term healing and relapse rate in 135 patients with duodenal ulcer who were treat...

journal_title：Gastroenterology

authors： Korman MG,Hansky J,Eaves ER,Schmidt GT

更新日期：1983-10-01 00:00:00

abstract：:It has been suggested that the lower esophageal sphincter (LES) plays an important role in preventing gastroesophageal reflux. This study was designed to determine if abolition of the LES alone is sufficient to induce gastroesophageal reflux and esophagitis. Studies were performed in the Australian brush-tailed possum...

journal_title：Gastroenterology

authors： De Carle DJ

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND & AIMS:As life expectancy increases, there are greater numbers of patients with liver diseases who require surgery or transplantation. Livers of older patients have significantly less reparative capacity following ischemia and reperfusion (I/R) injury, which occurs during these operations. There are no strat...

journal_title：Gastroenterology

authors： Wang JH,Ahn IS,Fischer TD,Byeon JI,Dunn WA Jr,Behrns KE,Leeuwenburgh C,Kim JS

更新日期：2011-12-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma is a devastating disease, and patient outcomes have not improved in decades. Treatments that target tumor cells have largely failed. This could be because research has focused on cancer cells and the influence of the stroma on tumor progression has been largely ignored. The focus of pa...

journal_title：Gastroenterology

authors： Apte MV,Wilson JS,Lugea A,Pandol SJ

更新日期：2013-06-01 00:00:00

abstract：:Phosphatase-mediated hydrolysis is the first step in the intestinal absorption of pyridoxal 5'-phosphate (PLP). Studies presented here evaluated the effects of PLP-protein binding and pH on intestinal hydrolysis in the rat. Models included in vitro PLP decay and in vivo PLP disappearance from perfused jejunal segments...

journal_title：Gastroenterology

authors： Middleton HM 3rd

更新日期：1986-08-01 00:00:00

abstract：:The effects of some newly developed tachykinin antagonists that are selective for the neurokinin (NK)-1 (L 668,169) or the NK-2 (MEN 10,207, L 659,877 and R 396) tachykinin receptor on the cholinergic and noncholinergic contraction and on the nonadrenergic noncholinergic relaxation produced by electrical field stimula...

journal_title：Gastroenterology

authors： Maggi CA,Giuliani S,Patacchini R,Santicioli P,Theodorsson E,Barbanti G,Turini D,Giachetti A

更新日期：1992-01-01 00:00:00