Abstract:
:In this in vitro study, the biocompatibility of acrylamide-based hydrogels such as acrylamide/crotonic and acrylamide/itaconic acid, prepared by using gamma-rays, has been investigated against some biochemical parameters of human serum. The swelling kinetics of acrylamide/crotonic and acrylamide/itaconic acid hydrogels are investigated in distilled water and physiological saline solution and some swelling and diffusion parameters have been calculated. For the analysis of biocompatibility, acrylamide/crotonic and acrylamide/itaconic acid hydrogels are incubated in 10 different human sera for 24 h and their biocompatibilities with some biochemical parameters have been investigated. No significant difference in values before and after the test procedures have been found. It is therefore concluded that acrylamide/crotonic and acrylamide/itaconic acid hydrogels are biocompatible.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Karadağ E,Saraydin D,Cetinkaya S,Güven Odoi
10.1016/0142-9612(96)80757-5subject
Has Abstractpub_date
1996-01-01 00:00:00pages
67-70issue
1eissn
0142-9612issn
1878-5905pii
0142961296807575journal_volume
17pub_type
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