Abstract：
:The distribution of beta-endorphin (1-27) immunoreactive cell bodies and fibres was studied in the diencephalon of the cat using an indirect immunoperoxidase technique. In the thalamus, almost all the immunoreactive fibres were found in the midline region and in nuclei located near the midline, whereas in the hypothalamus fibres containing beta-endorphin (1-27) were visualized extending by the whole structure. The hypothalamus showed a higher density of beta-endorphin (1-27) immunoreactive fibres than the thalamus, as well as immunoreactive cell bodies, since in the thalamus no beta-endorphin (1-27) immunoreactive neuron was located. The densest network of immunoreactive fibres was observed in the epithalamus (nucleus periventricularis anterior) and in the hypothalamic nuclei arcuatus, hypothalami ventromedialis, suprachiasmaticus, periventricularis hypothalami, hypothalamus dorsomedialis, area hypothalamica dorsalis, hypothalamus anterior, filiformis, hypothalamus posterior and regio praeoptica. In the hypothalamus, a high density of perikarya containing beta-endorphin (1-27) was observed in the nucleus arcuatus and a low density in the nucleus hypothalami ventromedialis. The distribution of beta-endorphin (1-27) immunoreactive fibres and perikarya is compared with the location of other neuropeptides in the cat diencephalon. Our findings reveal that b-endorphin (1-27) immunoreactive structures are widely distributed in the cat diencephalon, suggesting that the peptide might be involved in several physiological functions.
journal_name
Neuropeptidesjournal_title
Neuropeptidesauthors
Coveñas R,de León M,Narváez JA,Tramu G,Aguirre JA,González-Barón Sdoi
10.1016/s0143-4179(96)90072-4subject
Has Abstractpub_date
1996-06-01 00:00:00pages
261-71issue
3eissn
0143-4179issn
1532-2785pii
S0143-4179(96)90072-4journal_volume
30pub_type
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