Amnesic action of FMRFamide in rats.

Abstract:

:The effects of FMRFamide on passive avoidance behaviour and electroshock-induced amnesia following intracerebroventricular administration were studied in rats. FMRFamide given immediately after the learning trial, or 20 min before the retention trial, attenuated the avoidance response, thereby impairing the consolidation and retrieval processes. Electroshock induced amnesia when applied immediately after the learning trial. Treatment with FMRFamide facilitated the amnesia of the passive avoidance response. The results indicate that FMRFamide peptide belongs in the class of neuropeptide which are amnesic.

journal_name

Neuropeptides

journal_title

Neuropeptides

authors

Telegdy G,Bollók I

doi

10.1016/0143-4179(87)90017-5

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

157-63

issue

2

eissn

0143-4179

issn

1532-2785

pii

0143-4179(87)90017-5

journal_volume

10

pub_type

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