Hepatic injury and lethal shock in galactosamine-sensitized mice induced by the superantigen staphylococcal enterotoxin B.

abstract：:Epithelial renewal of the small intestine was measured in the Syrian hamster utilizing tritiated thymidine by standard autoradiographic and a scintillation counting technique. Scintillation counting of intestinal replicates proved to be as accurate as standard autoradiography. Average mucosal cell turnover was 71 +/- ...

journal_title：Gastroenterology

authors： Banwell JG,Lepot A,Hanke DW,Sigdestad C

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Over 60 studies have addressed the hypothesis that the risk of colorectal cancer is increased following cholecystectomy; these studies have yielded inconsistent findings. The aim of the present study was to quantitatively summarize the results from the collective studies. METHODS:A meta-analysis of the publ...

journal_title：Gastroenterology

authors： Giovannucci E,Colditz GA,Stampfer MJ

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of selectins in experimental colitis remains unknown. The aims of this study were to characterize the time-course expression of selectins in trinitrobenzene sulfonic acid (TNBS)-induced colitis, the functional role of selectins in colonic leukocyte-endothelial cell interactions, and the the...

journal_title：Gastroenterology

authors： Sans M,Salas A,Soriano A,Prats N,Gironella M,Pizcueta P,Elena M,Anderson DC,Piqué JM,Panés J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND & AIMS:Although bone marrow (BM) is known as a primary lymphoid organ, it also is known to harbor memory T cells, suggesting that this compartment is a preferential site for migration and/or selective retention of memory T cells. We here report the existence and the potential ability to induce colitis of the...

journal_title：Gastroenterology

authors： Nemoto Y,Kanai T,Makita S,Okamoto R,Totsuka T,Takeda K,Watanabe M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND & AIMS:Activated recombinant factor VII (rFVIIa) has been shown to be effective in correcting prolonged prothrombin time (PT) in cirrhotic patients. The main objective of this study was to evaluate the effect of 4 (5, 20, 80, and 120 microg/kg) doses of rFVIIa on correction of PT and the time to achieve hemo...

journal_title：Gastroenterology

authors： Jeffers L,Chalasani N,Balart L,Pyrsopoulos N,Erhardtsen E

更新日期：2002-07-01 00:00:00

abstract：:Development of an intraabdominal bile collection (biloma) usually occurs secondary to traumatic or iatrogenic injury including abdominal surgery, percutaneous catheter drainage, and transhepatic cholangiogram. We present a case of hepatic subcapsular biloma following endoscopic retrograde cholangiography and identifie...

journal_title：Gastroenterology

authors： Dupas JL,Mancheron H,Sevenet F,Delamarre J,Delcenserie R,Capron JP

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND & AIMS:The tumor necrosis factor (TNF)-alpha/TNF receptor system is critical for liver development because hepatocytes undergo apoptosis if the antiapoptotic cascades resulting in RelA NF-kappaB activation are not effective. Therefore, we studied the role of TNF-alpha in fulminant hepatic failure (FHF) and d...

journal_title：Gastroenterology

authors： Streetz K,Leifeld L,Grundmann D,Ramakers J,Eckert K,Spengler U,Brenner D,Manns M,Trautwein C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND & AIMS:The anti-cancer effects of vegetables and fruit have been investigated extensively, but the association between vegetable and fruit consumption and risk of hepatocellular carcinoma (HCC) has not been quantified. We performed a meta-analysis of observational studies to clarify the association. METHODS...

journal_title：Gastroenterology

authors： Yang Y,Zhang D,Feng N,Chen G,Liu J,Chen G,Zhu Y

更新日期：2014-11-01 00:00:00

abstract：:Using a radioimmunoassay which detect concentrations of alpha-fetoprotein as low as 5 ng per ml, 38% of 176 patients with viral hepatitis compared with health volunteers and patients with chronic diseases not affecting the liver. When separated into two groups based on histological classification of liver biopsy speci...

journal_title：Gastroenterology

authors： Bloomer JR,Waldmann TA,McIntire R,Klatskin G

更新日期：1975-02-01 00:00:00

abstract：:The nuclear lamina is a multi-protein lattice composed of A- and B-type lamins and their associated proteins. This protein lattice associates with heterochromatin and integral inner nuclear membrane proteins, providing links among the genome, nucleoskeleton, and cytoskeleton. In the 1990s, mutations in EMD and LMNA we...

journal_title：Gastroenterology

authors： Brady GF,Kwan R,Bragazzi Cunha J,Elenbaas JS,Omary MB

更新日期：2018-05-01 00:00:00

abstract：:Autophagy is a lysosomal pathway that degrades and recycles intracellular organelles and proteins to maintain energy homeostasis during times of nutrient deprivation and to remove damaged cell components. Recent studies have identified new functions for autophagy under basal and stressed conditions. In the liver and p...

journal_title：Gastroenterology

authors： Czaja MJ

更新日期：2011-06-01 00:00:00

abstract：:Somatostatin-14 and somatostatin-28 are biologically active peptides derived from the posttranslational cleavage of prosomatostatin. Because both peptides are found in variable concentrations in the gastrointestinal (GI) tract and pancreas, it has been contended that somatostatin-28 is either an intermediate in the pr...

journal_title：Gastroenterology

authors： Francis BH,Baskin DG,Saunders DR,Ensinck JW

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND/AIMS:Despite putative roles of calcium in biliary physiology and gallstone formation, quantitative aspects of calcium binding to bile salt (BS) monomers, simple micelles, mixed micelles, and vesicles, which constitute the lipid aggregates in bile, remain unexplored. METHODS:Calcium activity was measured usi...

journal_title：Gastroenterology

authors： Donovan JM,Leonard MR,Batta AK,Carey MC

更新日期：1994-09-01 00:00:00

abstract：:A 36-year-old woman was admitted to hospital with a first attack of acute intermittent porphyria. At the same time increased serum levels of amylase and lipase as well as an increased amylase clearance to creatinine clearance ratio were observed, permitting the diagnosis of acute pancreatitis. The etiology of the latt...

journal_title：Gastroenterology

authors： Kobza K,Gyr K,Neuhaus K,Gudat F

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND & AIMS:It is not clear whether H2-receptor antagonists (H2RAs) reduce the risk of gastrointestinal (GI) bleeding in aspirin users at high risk. We performed a double-blind randomized trial to compare the effects of a proton pump inhibitor (PPI) vs a H2RA antagonist in preventing recurrent upper GI bleeding a...

journal_title：Gastroenterology

authors： Chan FK,Kyaw M,Tanigawa T,Higuchi K,Fujimoto K,Cheong PK,Lee V,Kinoshita Y,Naito Y,Watanabe T,Ching JY,Lam K,Lo A,Chan H,Lui R,Tang RS,Sakata Y,Tse YK,Takeuchi T,Handa O,Nebiki H,Wu JC,Abe T,Mishiro T,Ng S

更新日期：2017-01-01 00:00:00

abstract：:Helicobacter pylori infects the stomach of half of the human population worldwide and causes chronic active gastritis, which can lead to peptic ulcer disease, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. The host immune response to the infection is ineffective, because the bacterium persists...

journal_title：Gastroenterology

authors： Wilson KT,Crabtree JE

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND/AIMS:Growth factors and their receptors play a role in healing ulcers of the rat. Somatostatin is a putative growth factor in the gastric mucosa with multiple functions mediated by specific receptors. Therefore, the distribution of somatostatin receptors was evaluated in the gastric mucosa of healing ulcers....

journal_title：Gastroenterology

authors： Reubi JC,Waser B,Schmassmann A,Halter F

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND & AIMS:Capillarization of the sinusoids in cirrhosis is proposed to reduce oxygen availability to the hepatocyte, resulting in the patterns of altered drug metabolism observed in cirrhosis. If this were true, drug metabolism in cirrhotic livers would be expected to be more sensitive to reduced oxygen deliver...

journal_title：Gastroenterology

authors： Hickey PL,McLean AJ,Angus PW,Choo EF,Morgan DJ

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND & AIMS:One approach to the development of targeted cancer chemotherapy exploits increased uptake of the agent into neoplastic cells. In this scenario, higher concentrations of the agent in cancer cells are responsible for differential killing, whereas the low concentration in normal human cells decreases sid...

journal_title：Gastroenterology

authors： Abe T,Unno M,Onogawa T,Tokui T,Kondo TN,Nakagomi R,Adachi H,Fujiwara K,Okabe M,Suzuki T,Nunoki K,Sato E,Kakyo M,Nishio T,Sugita J,Asano N,Tanemoto M,Seki M,Date F,Ono K,Kondo Y,Shiiba K,Suzuki M,Ohtani H,S

更新日期：2001-06-01 00:00:00

abstract：:Twenty-seven carriers of the hepatitis B surface antigen who underwent liver transplantation in Italy and Belgium for terminal Hepatitis delta virus (HDV) cirrhosis were investigated. In 22 of the patients, HDV infection recurred. Two patients died of coexisting HDV and hepatitis B virus (HBV) reactivation. Four patie...

journal_title：Gastroenterology

authors： Ottobrelli A,Marzano A,Smedile A,Recchia S,Salizzoni M,Cornu C,Lamy ME,Otte JB,De Hemptinne B,Geubel A

更新日期：1991-12-01 00:00:00

abstract：:Treatment options for inflammatory bowel disease (IBD) reflect a continuing shift from empiricism to strategies based on improved understanding of the pathophysiology of disease. In susceptible individuals, IBD appears to be the result of defective regulation of mucosal immune interactions with the enteric microflora....

journal_title：Gastroenterology

authors： Shanahan F

更新日期：2001-02-01 00:00:00

abstract：:To determine the effect of intraduodenal calcium on pancreatic, gallbladder, and gastric functions in healthy man, a validated perfusion method was employed to quantify total pancreatic, biliary, and gastric outputs during duodenal perfusion of either 6 mM, 12 mM,or 25 mM of elemental calcium (as isotonic calcium chlo...

journal_title：Gastroenterology

authors： Holtermuller KH,Mallagelada JR,McCall JT,Go VL

更新日期：1976-05-01 00:00:00

abstract：:Methyl tert-butyl ether dissolves cholesterol gallbladder stones when infused through a percutaneous transhepatic catheter. All gallstones, however, contain noncholesterol components that are insoluble in lipid solvents and may be too large to be aspirated through a small catheter or flushed from the gallbladder. To i...

journal_title：Gastroenterology

authors： Nelson PE,Moyer TP,Thistle JL

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND & AIMS:Ground-glass (GG) inclusions within hepatocytes are an important histopathologic marker of chronic hepatitis B virus (HBV) infection but may also be seen in Lafora's disease (myoclonus epilepsy), cyanamide alcohol aversion therapy, and type IV glycogenosis. We have noted a recent increased incidence o...

journal_title：Gastroenterology

authors： Lefkowitch JH,Lobritto SJ,Brown RS Jr,Emond JC,Schilsky ML,Rosenthal LA,George DM,Cairo MS

更新日期：2006-09-01 00:00:00

abstract：:Some of the most common symptoms of the inflammatory bowel diseases (IBD, which include ulcerative colitis and Crohn's disease) are abdominal pain, diarrhea, and weight loss. It is therefore not surprising that clinicians and patients have wondered whether dietary patterns influence the onset or course of IBD. The que...

journal_title：Gastroenterology

authors： Lee D,Albenberg L,Compher C,Baldassano R,Piccoli D,Lewis JD,Wu GD

更新日期：2015-05-01 00:00:00

abstract：:To examine the premise that exercise reduces the gastrointestinal transit time, we evaluated the effect of walking 4.5 km in an hour on mouth-to-cecum transit time. Twenty-three healthy volunteers, 9 men and 14 women, with an age range of 19-28 yr, were studied. After an overnight fast, the subjects ingested 10 g of l...

journal_title：Gastroenterology

authors： Meshkinpour H,Kemp C,Fairshter R

更新日期：1989-03-01 00:00:00

abstract：:Because approximately 80% of reported patients with somatostatinomas have gallstones, this study was performed to determine the effects of exogenous somatostatin on gallbladder emptying responses to liquid and solid meals, direct cholinergic stimulation by bethanechol, indirect cholinergic stimulation by sham feeding,...

journal_title：Gastroenterology

authors： Fisher RS,Rock E,Levin G,Malmud L

更新日期：1987-04-01 00:00:00

abstract：:A patient with a macroamylase in pleural fluid is described. A diagnosis of recurrent pleural effusion due to chronic relapsing pancreatitis had been made on the basis of hyperamylasemia, high pleural fluid amylase, and abdominal pain. The amylase in the pleural fluid as well as the serum was ultimately characterized ...

journal_title：Gastroenterology

authors： Zimmerman HM,Bank S,Buch P,Katzka I,Lendvai S

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells are the target of numerous immune-mediated liver diseases, yet their role in pathogenesis remains unclear because of difficulties in obtaining pure preparations. The aim of this study was to establish pure clones of immortalized murine intrahepatic biliary epithelial cells. M...

journal_title：Gastroenterology

authors： Paradis K,Le ON,Russo P,St-Cyr M,Fournier H,Bu D

更新日期：1995-10-01 00:00:00

abstract：:The effect of local intraarterial infusion of arginine vasopressin was studied in a vascularly perfused segment of cat ileum. Systemic arterial pressure (Pa), superior mesenteric arterial pressure (Pma), superior mesenteric venous pressure (Pv), blood flow (QB) and intestinal volume (V) were continuously monitored. In...

journal_title：Gastroenterology

authors： Quillen EW,Granger DN,Taylor AE

更新日期：1977-12-01 00:00:00