Gallstone dissolution in vitro using methyl tert-butyl ether: radiologic selection criteria.

abstract：:This study examines the effects of endotoxin on intestinal water and electrolyte transport in adult male rats. Endotoxin (1.55 mg/kg, intravenously) reduced in vivo colonic saline absorption 61% in 1 hour. In vitro unidirectional and net 22Na and 36Cl fluxes showed that endotoxin significantly decreased net colonic 22...

journal_title：Gastroenterology

authors： Ciancio MJ,Vitiritti L,Dhar A,Chang EB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND & AIMS:Fecal microbiota transplantation (FMT) is a highly effective therapy for recurrent Clostridium difficile infection (CDI). However, transferring undefined living bacteria entails uncontrollable risks for infectious and metabolic or malignant diseases, particularly in immunocompromised patients. We inve...

journal_title：Gastroenterology

authors： Ott SJ,Waetzig GH,Rehman A,Moltzau-Anderson J,Bharti R,Grasis JA,Cassidy L,Tholey A,Fickenscher H,Seegert D,Rosenstiel P,Schreiber S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND AIMS:To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes. We therefore aimed to characterize the genetic potential of the gut microbiome in PSC compared to ...

journal_title：Gastroenterology

authors： Kummen M,Thingholm LB,Rühlemann MC,Holm K,Hansen SH,Moitinho-Silva L,Liwinski T,Zenouzi R,Storm-Larsen C,Midttun Ø,McCann A,Ueland PM,Høivik ML,Vesterhus M,Trøseid M,Laudes M,Lieb W,Karlsen TH,Bang C,Schramm C,Fra

更新日期：2020-12-30 00:00:00

abstract：BACKGROUND & AIMS:Activating transcription factor 4 (ATF4) regulates genes involved in the inflammatory response, amino acid metabolism, autophagy, and endoplasmic reticulum stress. We investigated whether its activity is altered in patients with inflammatory bowel diseases (IBDs) and mice with enterocolitis. METHODS:...

journal_title：Gastroenterology

authors： Hu X,Deng J,Yu T,Chen S,Ge Y,Zhou Z,Guo Y,Ying H,Zhai Q,Chen Y,Yuan F,Niu Y,Shu W,Chen H,Ma C,Liu Z,Guo F

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND & AIMS:ob/ob mice are used to study the mechanisms that regulate the progression from steatosis to nonalcoholic steatohepatitis. The livers of ob/ob mice are depleted of CD4-positive natural killer cells, components of the innate immune system that induce anti-inflammatory cytokines. Although this may explai...

journal_title：Gastroenterology

authors： Li Z,Lin H,Yang S,Diehl AM

更新日期：2002-10-01 00:00:00

abstract：:Sporadic colorectal cancer (CRC) is a somatic genetic disease in which pathogenesis is influenced by the local colonic environment and the patient's genetic background. Consolidating the knowledge of genetic and epigenetic events that occur with initiation, progression, and metastasis of sporadic CRC has identified so...

journal_title：Gastroenterology

authors： Carethers JM,Jung BH

更新日期：2015-10-01 00:00:00

abstract：:Disappearance of symptoms, resolution of most biochemical abnormalities, and histologic improvement to mild chronic inflammation were accomplished in 69 of 123 patients (56%) with severe chronic active liver disease treated with corticosteroids for up to 6.5 yr. Remission of at least 6 mo duration was possible in 35 o...

journal_title：Gastroenterology

authors： Czaja AJ,Ammon HV,Summerskill WH

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with inflammatory bowel disease who are in remission and those who developed irritable bowel syndrome after enteric infection continue to have symptoms of diarrhea or constipation in the absence of overt inflammation, indicating motility dysfunction. We investigated whether oxidative stress d...

journal_title：Gastroenterology

authors： Choi K,Chen J,Mitra S,Sarna SK

更新日期：2011-10-01 00:00:00

abstract：:In dogs with Heidenhain pouches and gastric fistulas, we studied acid secretion in response to systemic or portal infusion of methionine-enkephalin (met-enkephalin), enkephalin-analog, or morphine. All these opiate compounds caused a dose-dependent increase in acid secretion under basal conditions and resulted in a si...

journal_title：Gastroenterology

authors： Konturek SJ,Tasler J,Cieszkowski M,Mikoś E,Coy DH,Schally AV

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND & AIMS:Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism, controlling cholesterol flow into cells, catabolism, and efflux. Cholesterol controls cell proliferation; disruptions in cholesterol metabolism have been associated with the development of colon cancer. We investigated ...

journal_title：Gastroenterology

authors： Lo Sasso G,Bovenga F,Murzilli S,Salvatore L,Di Tullio G,Martelli N,D'Orazio A,Rainaldi S,Vacca M,Mangia A,Palasciano G,Moschetta A

更新日期：2013-06-01 00:00:00

abstract：:Modern manometric and scintigraphic techniques were employed in an effort to determine the relationships between esophageal contractions and esophageal transit and clearance. The effects of direct cholinergic stimulation with bethanechol and blockade with atropine were evaluated in a total of 20 normal subjects and 13...

journal_title：Gastroenterology

authors： Phaosawasdi K,Malmud LS,Tolin RD,Stelzer F,Applegate G,Fisher RS

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND & AIMS:Adenosine mediates immune suppression and is generated by the ectonucleotidases CD39 (ENTPD1) and CD73 that are expressed on vascular endothelial cells and regulatory T cells (Tregs). Although tumor-infiltrating immune cells include Foxp3(+) Tregs, it is not clear whether local adenosine generation by...

journal_title：Gastroenterology

authors： Sun X,Wu Y,Gao W,Enjyoji K,Csizmadia E,Müller CE,Murakami T,Robson SC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND & AIMS:The goal of the study was to facilitate fat balance measurements with an appropriate intestinal marker for the transit of dietary fat and thereby eliminate the need for complete diet and fecal collections. METHODS:Dietary fat containing 5% sucrose polybehenate was fed in a semisynthetic diet to rats ...

journal_title：Gastroenterology

authors： Jandacek RJ,Heubi JE,Tso P

更新日期：2004-07-01 00:00:00

abstract：:Numerous epidemiologic studies suggest a relationship between lung cancer and peptic ulcer disease. Furthermore, various lung cancers synthesize and release a number of peptides such as gastrin and gastrin-releasing peptide that could cause acid hypersecretion; however, Zollinger-Ellison syndrome (ZES), because of a l...

journal_title：Gastroenterology

authors： Abou-Saif A,Lei J,McDonald TJ,Chakrabarti S,Waxman IF,Shojamanesh H,Schrump DS,Kleiner DE,Gibril F,Jensen RT

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND & AIMS:Beta-blockers are extensively used to prevent variceal bleeding in patients with large esophageal varices. It is not established if beta-blockers delay the growth of small varices. METHODS:A total of 161 patients with cirrhosis and small esophageal varices (F1 according to the classification of Beppu...

journal_title：Gastroenterology

authors： Merkel C,Marin R,Angeli P,Zanella P,Felder M,Bernardinello E,Cavallarin G,Bolognesi M,Donada C,Bellini B,Torboli P,Gatta A,Gruppo Triveneto per l'Ipertensione Portale.

更新日期：2004-08-01 00:00:00

abstract：:There is increasing evidence that ingested diet-borne components are involved in the pathogenesis of disorders such as inflammatory bowel diseases, atherosclerosis, and type 2 diabetes. Nutrients can have short- and long-term effects in shaping the composition of the microbiota. Western diets (enriched in fat, phospha...

journal_title：Gastroenterology

authors： Tilg H,Moschen AR

更新日期：2015-05-01 00:00:00

abstract：:A case of acute hypervitaminosis A complicating viral hepatitis is reported. Twenty days after presenting with hepatitis B, a 42-yr-old vegetarian developed acute hypervitaminosis A in the absence of recent, massive exposure to the vitamin. Findings included headache, confusion, skin desquamation, and hypercalcemia. P...

journal_title：Gastroenterology

authors： Hatoff DE,Gertler SL,Miyai K,Parker BA,Weiss JB

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND & AIMS:This study investigated whether obesity, diabetes, and other metabolic factors are independently associated with hepatocellular carcinoma (HCC), stratified by hepatitis B virus (HBV) and hepatitis C virus (HCV) serostatus, and explored the possible joint influence of obesity/diabetes and HBV/HCV infec...

journal_title：Gastroenterology

authors： Chen CL,Yang HI,Yang WS,Liu CJ,Chen PJ,You SL,Wang LY,Sun CA,Lu SN,Chen DS,Chen CJ

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND & AIMS:Human cervical cancer oncogene (HCCR-1) has appeared to act as a negative regulator of p53 and contributes to tumorigenesis of various organs including the colon. We identified the HCCR-1 binding protein deleted in polyposis 1 (DP1) and accessed the role of HCCR-1 and DP1 in colon tumorigenesis. METH...

journal_title：Gastroenterology

authors： Shin SM,Chung YJ,Oh ST,Jeon HM,Hwang LJ,Namkoong H,Kim HK,Cho GW,Hur SY,Kim TE,Lee YS,Park YG,Ko J,Kim JW

更新日期：2006-06-01 00:00:00

abstract：:Several studies suggest that bile salts are transported from the basolateral to the canalicular membrane of hepatocytes by a vesicular pathway, possibly in part via the Golgi complex. To test this hypothesis, the present study examined, in the perfused rat liver, the influence of the Na+ ionophore monensin on the bili...

journal_title：Gastroenterology

authors： Reynier MO,Abou Hashieh I,Crotte C,Carbuccia N,Richard B,Gérolami A

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND & AIMS:Endosonography-guided fine-needle aspiration biopsy (EUS-FNA) permits cytological confirmation of EUS findings. A multicenter prospective evaluation of EUS-FNA for primary diagnosis, staging, and/or follow-up purposes was undertaken. METHODS:EUS-FNA was performed in 457 patients with 554 lesions. Cli...

journal_title：Gastroenterology

authors： Wiersema MJ,Vilmann P,Giovannini M,Chang KJ,Wiersema LM

更新日期：1997-04-01 00:00:00

abstract：:A patient with recurrent gastrointestinal bleeding caused by hereditary hemorrhagic telangiectasia localized to the small intestine is described. The diagnosis was made by combining two recognized investigational tools-fiberoptic endoscopy and laparotomy. ...

journal_title：Gastroenterology

authors： Greenberg GR,Phillips MJ,Tovee EB,Jeejeebhoy KN

更新日期：1976-07-01 00:00:00

abstract：:To determine whether pancreatic polypeptide (PP) is a physiologic inhibitor of pancreatic secretion, we have studied the effects of normal rabbit serum and anti-PP serum on pancreatic secretion during infusion of a physiologic dose of PP or intragastric food instillation in dogs. Infusion of 180 pmol/kg X h of PP, pre...

journal_title：Gastroenterology

authors： de Jong AJ,Singer MV,Lamers CB

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND & AIMS:Idiopathic inflammatory bowel disease (IBD) is associated with bone loss in more than 30% of cases. Nevertheless, the pathogenesis of the bone loss is uncertain. The aim of this study was to investigate the bone loss and underlying mechanisms using an animal model of IBD. METHODS:Severe colitis was i...

journal_title：Gastroenterology

authors： Lin CL,Moniz C,Chambers TJ,Chow JW

更新日期：1996-11-01 00:00:00

abstract：:In the previous decade, comprehensive genomic analyses have yielded important insights about the genetic alterations that underlie pancreatic tumorigenesis. Whole-exome and whole-genome sequencing of pancreatic ductal adenocarcinomas have confirmed the critical driver genes altered in the majority of pancreatic cancer...

journal_title：Gastroenterology

authors： Wood LD,Yurgelun MB,Goggins MG

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND/AIMS:Hepatic vein thrombosis is thought to be manifested by ascites, abdominal pain, and hepatomegaly, with a uniformly poor prognosis. However, new imaging techniques allow for the diagnosis of hepatic vein thrombosis in asymptomatic cases. The aim of our study was to re-evaluate symptoms and prognosis in p...

journal_title：Gastroenterology

authors： Hadengue A,Poliquin M,Vilgrain V,Belghiti J,Degott C,Erlinger S,Benhamou JP

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatic bile salt secretion is an essential function of vertebrate liver. Rat and mouse bile salt export pump (Bsep) are adenosine triphosphate (ATP)-dependent bile salt transporters. Mutations in human BSEP were identified as the cause of progressive familial intrahepatic cholestasis type 2. BSEP pro...

journal_title：Gastroenterology

authors： Noé J,Stieger B,Meier PJ

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND & AIMS:In searching for effects of acetaminophen (APAP) on hepatocytes downstream of its metabolism that may participate in hepatotoxicity, we examined the role of stress kinases. METHODS:Mouse hepatocytes and C57BL/6 mice were administered a toxic dose of APAP with or without SP600125, a chemical c-jun N-t...

journal_title：Gastroenterology

authors： Gunawan BK,Liu ZX,Han D,Hanawa N,Gaarde WA,Kaplowitz N

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND/AIMS:Human colonic epithelium produces large amounts of mucin. The aim of this study was to examine mucin biosynthesis in the human colon. METHODS:Human colonic mucin was isolated using CsCl density gradients, and polyclonal antiserum was raised. Biosynthesis of colonic mucins was studied by labeling coloni...

journal_title：Gastroenterology

authors： Tytgat KM,Büller HA,Opdam FJ,Kim YS,Einerhand AW,Dekker J

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Although it has recently become possible to detect hepatitis C viral antigens in liver biopsy specimens, the frequency and clinical significance of this finding remains uncertain. Therefore, 49 liver biopsy specimens from 35 patients with hepatitis C were studied to make these assessments. METHODS:Hepatitis...

journal_title：Gastroenterology

authors： Di Bisceglie AM,Hoofnagle JH,Krawczynski K

更新日期：1993-09-01 00:00:00