Patterns of hepatitis delta virus reinfection and disease in liver transplantation.

abstract：:In order to discover the effect of bile acid synthesis on cholesterol secretion into the bile, 7 rhesus monkeys were studied at various stable interruptions of the enterohepatic circulation of bile acids. In 4 animals, 2.5 and 7.5% interruptions were compared; 2.5 and 15% interruptions were compared in 5 animals. Ther...

journal_title：Gastroenterology

authors： Strasberg SM,Petrunka CN,Ilson RG

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Although cholesterol is the most abundant sterol in animal tissues, oxidized products of cholesterol (oxysterols) also occur in mammalian organs and blood and are cytotoxic, atherogenic, and carcinogenic. However, the presence of oxysterols in bile or gallstones has never been reported. METHODS:Fre...

journal_title：Gastroenterology

authors： Haigh WG,Lee SP

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND & AIMS:Studies in gastrin-deficient mice have demonstrated critical roles for gastrin peptides in the regulation of gastric acid secretion, but the relative contributions of amidated (G-17) and glycine-extended (G17-Gly) gastrin remain unclear. We examined the effects of these 2 forms of gastrin on acid secr...

journal_title：Gastroenterology

authors： Chen D,Zhao CM,Dockray GJ,Varro A,Van Hoek A,Sinclair NF,Wang TC,Koh TJ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND & AIMS:We assessed the risk of ulcers with low-dose aspirin and the interaction of low-dose aspirin with a COX-2 selective inhibitor in a double-blind trial that compared placebo, low-dose aspirin, rofecoxib + low-dose aspirin, and ibuprofen. METHODS:Osteoarthritis patients > or =50 years of age without ulc...

journal_title：Gastroenterology

authors： Laine L,Maller ES,Yu C,Quan H,Simon T

更新日期：2004-08-01 00:00:00

abstract：:The authors' previous observation that many of the monoclonal antibodies against Helicobacter pylori cross-react with the cells of the human gastric mucosa prompted them to investigate the possibility that gastric self-antigens cross-reacting with H. pylori could be involved in the immune response against this organis...

journal_title：Gastroenterology

authors： Negrini R,Lisato L,Zanella I,Cavazzini L,Gullini S,Villanacci V,Poiesi C,Albertini A,Ghielmi S

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with chronic hepatitis C and persistently normal alanine aminotransferase (ALT) levels have been routinely excluded from large randomized treatment trials; consequently, the efficacy and safety of antiviral therapy in this population are unknown. METHODS:Patients with at least 3 normal ALT v...

journal_title：Gastroenterology

authors： Zeuzem S,Diago M,Gane E,Reddy KR,Pockros P,Prati D,Shiffman M,Farci P,Gitlin N,O'Brien CB,Lamour F,Lardelli P,PEGASYS Study NR16071 Investigator Group.

更新日期：2004-12-01 00:00:00

abstract：:Three analogues of the carboxyl-terminal tricosapeptide of secretin (S5-27), one with glutamine replacing glutamic acid in position 9 (9-Gln-S5-27), a second with asparagine substituted for aspartic acid in position 15 (15-Asn-S5-27), and a third with both replacements (9-Gln-15-Asn-S5-27) were tested for their abilit...

journal_title：Gastroenterology

authors： Gardner JD,Conlon TP,Fink ML,Bodanszky M

更新日期：1976-12-01 00:00:00

abstract：:An adult patient with chronic idiopathic intestinal pseudo-obstruction maintained on home parenteral nutrition for 6 consecutive years died from cardiomyopathy and ventricular fibrillation. Postmortem examination of the heart revealed widespread myocytolysis and replacement fibrosis similar to that seen in the seleniu...

journal_title：Gastroenterology

authors： Fleming CR,Lie JT,McCall JT,O'Brien JF,Baillie EE,Thistle JL

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND & AIMS:Hereditary colorectal cancer is associated most commonly with the hereditary nonpolyposis colorectal cancer or familial adenomatous polyposis syndromes. We investigated the prevalence of early onset colorectal cancer and the frequency of p53 germline mutations in 64 families from a Li-Fraumeni syndrom...

journal_title：Gastroenterology

authors： Wong P,Verselis SJ,Garber JE,Schneider K,DiGianni L,Stockwell DH,Li FP,Syngal S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND & AIMS:De novo lipogenesis is believed to be involved in oncogenesis. We investigated the role of aberrant lipid biosynthesis in the pathogenesis of human hepatocellular carcinoma (HCC). METHODS:We evaluated expression of enzymes that regulate lipogenesis in human normal liver tissues and HCC and surroundin...

journal_title：Gastroenterology

authors： Calvisi DF,Wang C,Ho C,Ladu S,Lee SA,Mattu S,Destefanis G,Delogu S,Zimmermann A,Ericsson J,Brozzetti S,Staniscia T,Chen X,Dombrowski F,Evert M

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND & AIMS:Some patients with irritable bowel syndrome with diarrhea (IBS-D) have intestinal hyperpermeability, which contributes to their diarrhea and abdominal pain. MicroRNA 29 (MIR29) regulates intestinal permeability in patients with IBS-D. We investigated and searched for targets of MIR29 and investigated ...

journal_title：Gastroenterology

authors： Zhou Q,Costinean S,Croce CM,Brasier AR,Merwat S,Larson SA,Basra S,Verne GN

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND & AIMS:Cytotoxic T cells have been suggested to be responsible for lysis of hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency, kinetics, phenotype, and capacity for clonal expansion of circulating HBV-specific CD8 cells were analyzed directly in patients with acute HB...

journal_title：Gastroenterology

authors： Maini MK,Boni C,Ogg GS,King AS,Reignat S,Lee CK,Larrubia JR,Webster GJ,McMichael AJ,Ferrari C,Williams R,Vergani D,Bertoletti A

更新日期：1999-12-01 00:00:00

abstract：:Decreases in arterial pH markedly increase sodium, chloride, and water absorption in the normal ileum and can reverse ongoing cholera toxin-induced secretion. In the current study we examined whether these effects of pH are evident in other models of ileal secretion, and in a model of increased absorption. Rats were a...

journal_title：Gastroenterology

authors： Charney AN,Ingrassia PM,Thaler SM,Keane MG

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND & AIMS:Activated recombinant factor VII (rFVIIa) has been shown to be effective in correcting prolonged prothrombin time (PT) in cirrhotic patients. The main objective of this study was to evaluate the effect of 4 (5, 20, 80, and 120 microg/kg) doses of rFVIIa on correction of PT and the time to achieve hemo...

journal_title：Gastroenterology

authors： Jeffers L,Chalasani N,Balart L,Pyrsopoulos N,Erhardtsen E

更新日期：2002-07-01 00:00:00

abstract：:The effects of hypothalamic microinfusions of cholecystokinin octapeptide and its antagonist L364,718 on cecocolonic myoelectrical activity were evaluated by electromyography in fasted and fed rats. The rats were chronically fitted with electrodes implanted on the cecum and proximal colon and cannulas placed bilateral...

journal_title：Gastroenterology

authors： Liberge M,Arruebo MP,Bueno L

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND & AIMS:Microsatellite instability is a property of most tumors occurring in the context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%-15% of apparently sporadic colorectal cancers, and it has been hypothesized that this instability may indicate a genetic predisposition to colonic ca...

journal_title：Gastroenterology

authors： Samowitz WS,Slattery ML,Kerber RA

更新日期：1995-12-01 00:00:00

abstract：:Excretion of hydrogen in breath commonly persists despite an overnight fast. Although elevation of hydrogen concentration above the fasting value after administration of a test sugar is evidence of malabsorption, the significance of the fasting value itself is unknown. We determined the normal limits of fasting breath...

journal_title：Gastroenterology

authors： Perman JA,Modler S,Barr RG,Rosenthal P

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatic acinar cells are used to study regulated exocytosis. We investigated the role of interferon regulatory factor-2 (IRF2) in exocytosis in pancreatic acinar cells. METHODS:Pancreas tissues from Irf2⁺/⁺, Irf2⁺/⁻), and Irf2⁻/⁻ mice were examined by microscopy, immunohistochemical, and immunoblo...

journal_title：Gastroenterology

authors： Mashima H,Sato T,Horie Y,Nakagawa Y,Kojima I,Ohteki T,Ohnishi H

更新日期：2011-09-01 00:00:00

abstract：:Epithelial renewal of the small intestine was measured in the Syrian hamster utilizing tritiated thymidine by standard autoradiographic and a scintillation counting technique. Scintillation counting of intestinal replicates proved to be as accurate as standard autoradiography. Average mucosal cell turnover was 71 +/- ...

journal_title：Gastroenterology

authors： Banwell JG,Lepot A,Hanke DW,Sigdestad C

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND & AIMS:Gastroesophageal reflux typically occurs after meals. During dual gastric and esophageal pH monitoring, we observed that postprandial refluxate was often more acidic than the gastric contents. This study aimed to investigate this phenomenon. METHODS:Dual gastric and esophageal pH tracings were analyz...

journal_title：Gastroenterology

authors： Fletcher J,Wirz A,Young J,Vallance R,McColl KE

更新日期：2001-10-01 00:00:00

abstract：:One of the least anticipated and less heralded outcomes of mouse genetics has been to rediscover whole organism physiology. Among the many unexpected findings that it has brought to our attention has been the realization that gut-derived serotonin is a hormone-inhibiting bone formation. The importance of this discover...

journal_title：Gastroenterology

authors： Karsenty G,Gershon MD

更新日期：2011-08-01 00:00:00

abstract：:The site and mechanism of alpha-[5-methyl-3-H]tocopherol absorption was investigated using everted rat small bowel sacs incubated in a micellar medium. Mean plus or minus SE absorption rates of the vitamin at 300 muM incubation solution concentration by proximal, medial, and distal small bowel segments were 2.2 plus o...

journal_title：Gastroenterology

authors： Hollander D,Rim E,Muralidhara KS

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND & AIMS:According to the National Center for Health Statistics (NCHS), chronic liver disease and cirrhosis is the 12(th) leading cause of death in the United States. However, this single descriptor might not adequately enumerate all deaths from liver disease. The aim of our study was to update data on liver m...

journal_title：Gastroenterology

authors： Asrani SK,Larson JJ,Yawn B,Therneau TM,Kim WR

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND & AIMS:Nonalcoholic chronic pancreatitis is usually idiopathic and often associated with cystic fibrosis gene (CFTR) mutations. It is unknown whether pancreatitis risk correlates with having 1 or 2 CFTR mutations, abnormal epithelial ion transport, or mutations of other genes. METHODS:We tested 39 patients ...

journal_title：Gastroenterology

authors： Noone PG,Zhou Z,Silverman LM,Jowell PS,Knowles MR,Cohn JA

更新日期：2001-12-01 00:00:00

abstract：:Intraarterial vasopressin has been reported to be effective in the treatment of massive upper gastrointestinal hemorrhage. A prospective, controlled clinical trial comparing conventional treatment with conventional therapy plus intraarterial vasopressin was undertaken. Sixty episodes of upper gastrointestinal hemorrha...

journal_title：Gastroenterology

authors： Conn HO,Ramsby GR,Storer EH,Mutchnick MG,Joshi PH,Phillips MM,Cohen GA,Fields GN,Petroski D

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND & AIMS:Calcitonin gene-related peptide (CGRP) protects the gastric mucosa against injurious stimuli in various experimental models. The underlying mechanism could be the increase in gastric mucosal blood flow (GMBF). A number of endogenous vasodilators exert their effects through the activation of adenosine ...

journal_title：Gastroenterology

authors： Doi K,Nagao T,Kawakubo K,Ibayashi S,Aoyagi K,Yano Y,Yamamoto C,Kanamoto K,Iida M,Sadoshima S,Fujishima M

更新日期：1998-01-01 00:00:00

abstract：:Erythromycin has been shown to act as a motilin agonist by binding to motilin receptors on gastrointestinal smooth muscle and to improve the severely impaired gastric emptying in patients with diabetic gastroparesis. To elucidate the motor pattern that accounts for this accelerated emptying, the effect of 200 mg eryth...

journal_title：Gastroenterology

authors： Annese V,Janssens J,Vantrappen G,Tack J,Peeters TL,Willemse P,Van Cutsem E

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately 10% of children on the liver transplant wait-list in the United States die every year. We examined deceased donor liver offer acceptance patterns and their contribution to pediatric wait-list mortality. METHODS:We performed a retrospective cohort study of children on the US liver transp...

journal_title：Gastroenterology

authors： Hsu EK,Shaffer ML,Gao L,Sonnenday C,Volk ML,Bucuvalas J,Lai JC

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND & AIMS:Gastroesophageal reflux is common among patients with postnasal drainage. We investigated whether proton pump inhibitor therapy improved symptoms in patients with postnasal drainage without sinusitis or allergies. METHODS:In a parallel-group, double-blind, multi-specialty trial, we randomly assigned ...

journal_title：Gastroenterology

authors： Vaezi MF,Hagaman DD,Slaughter JC,Tanner SB,Duncavage JA,Allocco CT,Sparkman C,Clement LE,Wasden CM,Wirth D,Goutte M,McCafferty BA,Lanza DC

更新日期：2010-12-01 00:00:00

abstract：:Numerous epidemiologic studies suggest a relationship between lung cancer and peptic ulcer disease. Furthermore, various lung cancers synthesize and release a number of peptides such as gastrin and gastrin-releasing peptide that could cause acid hypersecretion; however, Zollinger-Ellison syndrome (ZES), because of a l...

journal_title：Gastroenterology

authors： Abou-Saif A,Lei J,McDonald TJ,Chakrabarti S,Waxman IF,Shojamanesh H,Schrump DS,Kleiner DE,Gibril F,Jensen RT

更新日期：2001-04-01 00:00:00