A meta-analysis of cholecystectomy and risk of colorectal cancer.

abstract：BACKGROUND & AIMS:Biomarkers are needed to risk stratify after chemoradiotherapy for localized esophageal cancer. These could improve identification of patients at risk for cancer progression and selection of additional therapy. METHODS:We performed deep sequencing (CAncer Personalized Profiling by deep Sequencing, [C...

journal_title：Gastroenterology

authors： Azad TD,Chaudhuri AA,Fang P,Qiao Y,Esfahani MS,Chabon JJ,Hamilton EG,Yang YD,Lovejoy A,Newman AM,Kurtz DM,Jin M,Schroers-Martin J,Stehr H,Liu CL,Hui AB,Patel V,Maru D,Lin SH,Alizadeh AA,Diehn M

更新日期：2020-02-01 00:00:00

abstract：:We performed 92 computed tomography-guided percutaneous needle aspirations of pancreatic inflammatory masses in 60 patients suspected of harboring pancreatic infection. Thirty-six patients (60%) were found by Gram stain and culture to have a total of 41 separate episodes of pancreatic infection. Among 42 aspirates jud...

journal_title：Gastroenterology

authors： Gerzof SG,Banks PA,Robbins AH,Johnson WC,Spechler SJ,Wetzner SM,Snider JM,Langevin RE,Jay ME

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND & AIMS:Hydrophobic bile acids have been implicated in the pathogenesis of cholestatic liver injury. The hypothesis that hydrophobic bile acid toxicity is mediated by oxidant stress in an in vivo rat model was tested in this study. METHODS:A dose-response study of bolus intravenous (i.v.) taurochenodeoxychol...

journal_title：Gastroenterology

authors： Sokol RJ,McKim JM Jr,Goff MC,Ruyle SZ,Devereaux MW,Han D,Packer L,Everson G

更新日期：1998-01-01 00:00:00

abstract：:In ilea of spontaneously infested guinea pigs, we examined the interface between the plasma membranes of cryptosporidia and absorptive cells using thin section and freeze fracture techniques. Initially, cryptosporidia invaginate microvilli, and the resulting redundant folds of membrane envelop the protozoan, thereby i...

journal_title：Gastroenterology

authors： Marcial MA,Madara JL

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Somatostatin inhibits pancreatic exocrine secretion in intact animals but not in vitro, suggesting an indirect effect. The present study examined the influence of extrapancreatic nerves and intrapancreatic cholinergic activity on somatostatin-induced inhibition of pancreatic exocrine secretion in conscious d...

journal_title：Gastroenterology

authors： Kuvshinoff BW,Brodish RJ,James L,McFadden DW,Fink AS

更新日期：1993-08-01 00:00:00

abstract：:To determine the frequency and significance of alpha-fetoprotein elevation in severe hepatitis B surface antigen-negative chronic active hepatitis, 558 serum samples obtained from 83 patients were tested by an immunoenzymometric assay. All patients received corticosteroids and sampling occurred at 6-12-mo intervals du...

journal_title：Gastroenterology

authors： Czaja AJ,Beaver SJ,Wood JR,Klee GG,Go VL

更新日期：1987-10-01 00:00:00

abstract：:A patient who developed obstructive jaundice as a complication of a liver biopsy is presented. The jaundice was found to be attributable to obstruction of the biliary tree at the level of the bifurcation by an intrahepatic hematoma. The patient had a complete and spontaneous recovery. ...

journal_title：Gastroenterology

authors： Chiprut RO,Greenwald RA,Morris SJ,Zeppa R,Schiff ER

更新日期：1978-01-01 00:00:00

abstract：:Concern has arisen about the development of hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV) infection treated with direct-acting antivirals (DAAs). To identify patients at risk for HCC, we evaluated serum levels of immune mediators before, during, and after DAA treatment of HCV infection. Our s...

journal_title：Gastroenterology

authors： Debes JD,van Tilborg M,Groothuismink ZMA,Hansen BE,Schulze Zur Wiesch J,von Felden J,de Knegt RJ,Boonstra A

更新日期：2018-02-01 00:00:00

abstract：:Ceftriaxone, a semisynthetic third-generation cephalosporin, has recently been associated with biliary sludge formation. Analysis of the biliary concretions induced by this agent shows a calcium salt of ceftriaxone. The present in vitro studies were undertaken to provide insight into the pathogenesis of ceftriaxone-as...

journal_title：Gastroenterology

authors： Shiffman ML,Keith FB,Moore EW

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND/AIMS:Approximately 50% of patients with functional dyspepsia have Helicobacter pylori infection; it remains controversial whether this infection causes chronic symptoms, but rigorously conducted therapeutic trials should establish whether H. pylori plays a role in functional dyspepsia. The aim here was to de...

journal_title：Gastroenterology

authors： Talley NJ

更新日期：1994-05-01 00:00:00

abstract：:Reduction in caloric intake was associated with a greater absolute rise in the serum bilirubin concentration in patients with Gilbert's syndrome and partial hepatic bilirubin uridine diphosphate glucuronyltransferase (UDPG-T) dysfunction compared to patients with hemolytic unconjugated hyperbilirubinemia and normal su...

journal_title：Gastroenterology

authors： Felsher BF,Carpio NM

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:Newly synthesized apical membrane proteins in hepatocytes go first to the basolateral membrane, from which they are retrieved and delivered to the apical domain. The goal of the present study was to identify the vesicular carriers of these molecules. METHODS:The common bile duct of rats was ligated for 10-7...

journal_title：Gastroenterology

authors： Barr VA,Hubbard AL

更新日期：1993-08-01 00:00:00

abstract：:Circadian changes in drug absorption have been documented for several orally administered drugs in humans. To determine whether gastric emptying could account for these changes, morning (8 AM) and evening (8 PM) gastric emptying rates were measured in 16 healthy male subjects synchronized with diurnal activity and noc...

journal_title：Gastroenterology

authors： Goo RH,Moore JG,Greenberg E,Alazraki NP

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatitis C virus (HCV) uses several host factors to infect and replicate in human hepatocytes. Cyclophilin A (CypA) is required for viral replication, and CypA inhibitors are in development. We investigated the effects of nonsynonymous single nucleotide polymorphisms (SNPs) in the region of peptidyl-...

journal_title：Gastroenterology

authors： von Hahn T,Schiene-Fischer C,Van ND,Pfaender S,Karavul B,Steinmann E,Potthoff A,Strassburg C,Hamdi N,Abdelaziz AI,Sarrazin C,Müller T,Berg T,Trépo E,Wedemeyer H,Manns MP,Pietschmann T,Ciesek S

更新日期：2012-08-01 00:00:00

abstract：:We have quantified neurotransmitter changes in the rat jejunum in which the myenteric neurons were ablated by serosal application of benzalkonium chloride. Within 2 days after benzalkonium chloride treatment, there was a 40% reduction in the activity of choline acetyltransferase, a specific marker for cholinergic neur...

journal_title：Gastroenterology

authors： Dahl JL,Bloom DD,Epstein ML,Fox DA,Bass P

更新日期：1987-02-01 00:00:00

abstract：:The relationship between renal tubular acidosis (RTA) and copper metabolism has been investigated in a group of 18 patients with primary biliary cirrhosis. RTA, considered when urinary pH remained above 5.4 after an oral load of ammonium chloride of 0.1 g/kg body wt, was found in 6 patients (33%). Plasma copper concen...

journal_title：Gastroenterology

authors： Parés A,Rimola A,Bruguera M,Mas E,Rodés J

更新日期：1981-04-01 00:00:00

abstract：:Twenty-nine patients with esophageal symptoms and contraction abnormalities of the esophageal body completed a 6-wk, double-blind, placebo-controlled trial of trazodone (100-150 mg/day). Measures of esophageal and psychologic symptoms were completed at entry and at each follow-up visit. Esophageal manometry was repeat...

journal_title：Gastroenterology

authors： Clouse RE,Lustman PJ,Eckert TC,Ferney DM,Griffith LS

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND & AIMS:Development of pancreatic ductal adenocarcinoma (PDA) involves acinar to ductal metaplasia and genesis of tuft cells. It has been a challenge to study these rare cells because of the lack of animal models. We investigated the role of tuft cells in pancreatic tumorigenesis. METHODS:We performed studie...

journal_title：Gastroenterology

authors： DelGiorno KE,Chung CY,Vavinskaya V,Maurer HC,Novak SW,Lytle NK,Ma Z,Giraddi RR,Wang D,Fang L,Naeem RF,Andrade LR,Ali WH,Tseng H,Tsui C,Gubbala VB,Ridinger-Saison M,Ohmoto M,Erikson GA,O'Connor C,Shokhirev MN,Hah

更新日期：2020-11-01 00:00:00

abstract：:Twenty-one of 52 patients with regional enteritis had low serum zinc concentrations on initial testing. Fourteen of 31 patients followed longitudinally had low serum zinc concentrations. Two patients are presented as case reports who developed acrodermatitis skin lesions that responded to zinc therapy. Hypogonadism, g...

journal_title：Gastroenterology

authors： McClain C,Soutor C,Zieve L

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND & AIMS:We aimed to identify long noncoding RNAs (lncRNAs) that are up-regulated in gastric cancer tissues from patients and study their function in gastric tumor metastasis. METHODS:We collected gastric tumor and nontumor tissues from patients in China and analyzed levels of lncRNAs by microarray analysis, ...

journal_title：Gastroenterology

authors： Zhuo W,Liu Y,Li S,Guo D,Sun Q,Jin J,Rao X,Li M,Sun M,Jiang M,Xu Y,Teng L,Jin Y,Si J,Liu W,Kang Y,Zhou T

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND & AIMS:Recombinant human interleukin 11 (rhIL-11) is a cytokine with thrombocytopoietic activity and anti-inflammatory and mucosal protective effects. The objectives of this study were to investigate the safety and tolerability of rhIL-11 in patients with Crohn's disease and to explore the effects of dose an...

journal_title：Gastroenterology

authors： Sands BE,Bank S,Sninsky CA,Robinson M,Katz S,Singleton JW,Miner PB,Safdi MA,Galandiuk S,Hanauer SB,Varilek GW,Buchman AL,Rodgers VD,Salzberg B,Cai B,Loewy J,DeBruin MF,Rogge H,Shapiro M,Schwertschlag US

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND & AIMS:Long-term data on the risk of colorectal cancer according to dose, duration, and consistency of aspirin therapy are limited. METHODS:We conducted a prospective study of 47,363 male health professionals who were ages 40-75 years at enrollment in 1986. Biennially, we collected data on aspirin use, othe...

journal_title：Gastroenterology

authors： Chan AT,Giovannucci EL,Meyerhardt JA,Schernhammer ES,Wu K,Fuchs CS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatic lipid retention (steatosis) predisposes hepatitis. We investigated the mechanisms of lymphocyte homing to fatty liver and the role of lipopolysaccharide (LPS) in the onset of inflammation in ob/ob mice. METHODS:We decreased intestinal bacterial compounds by oral antibiotic treatment to test t...

journal_title：Gastroenterology

authors： Bigorgne AE,Bouchet-Delbos L,Naveau S,Dagher I,Prévot S,Durand-Gasselin I,Couderc J,Valet P,Emilie D,Perlemuter G

更新日期：2008-05-01 00:00:00

abstract：:Intracellular microelectrodes were used to evaluate electrical properties of the cell membranes in Necturus antral mucosa during exposure to luminal acid alone (pH 4) or to 5 mmol/L aspirin [acetylsalicylic acid (ASA)] in the presence of luminal acid. When nutrient solutions were buffered by HCO3- (pH 7.3), ASA modera...

journal_title：Gastroenterology

authors： Soybel DI,Davis MB,West AB

更新日期：1992-11-01 00:00:00

abstract：:The anatomical extent of fiberoptic sigmoidoscopy was determined by placing a clip on the colonic mucosa and subsequently locating the clip on barium enema. A 60 cm exam viewed the entire sigmoid colon in 81% of patients. Exams of 50-55 cm, 40-45 cm, and 30-35 cm extent viewed the entire sigmoid colon in 68%, 27%, and...

journal_title：Gastroenterology

authors： Lehman GA,Buchner DM,Lappas JC

更新日期：1983-04-01 00:00:00

abstract：:Encephalopathy in liver disease may be unresponsive to protein restriction, lactulose, and neomycin. Zinc supplements have been reported to improve psychometric performance in liver cirrhosis, but the importance of zinc deficiency in overt hepatic encephalopathy has not yet been clearly established. A patient with sev...

journal_title：Gastroenterology

authors： Van der Rijt CC,Schalm SW,Schat H,Foeken K,De Jong G

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND & AIMS:Foodborne illness affects 15% of the US population each year, and is a risk factor for irritable bowel syndrome (IBS). We evaluated risk of, risk factors for, and outcomes of IBS after infectious enteritis. METHODS:We performed a systematic review of electronic databases from 1994 through August 31, ...

journal_title：Gastroenterology

authors： Klem F,Wadhwa A,Prokop LJ,Sundt WJ,Farrugia G,Camilleri M,Singh S,Grover M

更新日期：2017-04-01 00:00:00

abstract：:Jejunal absorption of acetate, propionate, and butyrate--the three predominant short chain fatty acids (SCFA's) in small and large intestinal contents--was studied in 5 volunteer subjects. A triple-lumen perfusion technique was employed; the test solutions were isotonic and contained 0, 5, 10, 25, 40, or 50 mM of a SC...

journal_title：Gastroenterology

authors： Schmitt MG Jr,Soergel KH,Wood CM

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND/AIMS:The diagnosis of cholangiocarcinoma in primary sclerosing cholangitis (PSC), even with the use of current imaging techniques and brush cytology, is difficult and particularly important in patients being assessed for liver transplantation. This study investigated the accuracy of serum levels of a combina...

journal_title：Gastroenterology

authors： Ramage JK,Donaghy A,Farrant JM,Iorns R,Williams R

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal lactase activity is high in all healthy human babies, but in adults a genetic polymorphism, which acts in cis to the lactase gene, determines high or low messenger RNA (mRNA) expression and activity (lactase persistence and nonpersistence, respectively). Our aim was to investigate the onset...

journal_title：Gastroenterology

authors： Wang Y,Harvey CB,Hollox EJ,Phillips AD,Poulter M,Clay P,Walker-Smith JA,Swallow DM

更新日期：1998-06-01 00:00:00