Abstract:
:Cervical cytology specimens prepared as monolayers were analyzed with a combination of high-resolution single-cell image analysis and lower-resolution contextual image analysis. For the latter, quantitative features of cluster architecture, object distribution and background were used to mimic the pathologists global assessment of a specimen. Contextual analysis correctly classified 81% of the cases for diagnosis, about on a par with the companion single-cell cytometric analysis. Contextual and single cell analysis complemented each other, yielding greater accuracy when the two methods were combined. Additional applications of contextual analysis are discussed.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Zahniser DJ,Isenstein LM,Hutchinson MLdoi
10.1016/0304-3835(94)90096-5subject
Has Abstractpub_date
1994-03-15 00:00:00pages
139-44issue
2-3eissn
0304-3835issn
1872-7980pii
0304-3835(94)90096-5journal_volume
77pub_type
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